Clostridium difficile infection history and symptoms: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Siren|Clostridium difficile infection}} | {{Siren|Clostridium difficile infection}} | ||
{{Clostridium difficile}} | {{Clostridium difficile infection}} | ||
{{CMG}}; {{AE}} {{YD}} | {{CMG}}; {{AE}} {{YD}} | ||
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Clinical manifestations may range from an asymptomatic course to a severe/fatal presentation. | Clinical manifestations may range from an asymptomatic course to a severe/fatal presentation. | ||
=== Common | === Common Symptoms === | ||
* Acute-onset, foul-smelling watery [[diarrhea]] with or without pus. Diarrhea may occasionally be [[Bloody diarrhea|bloody]]. Diarrhea may be relieved by passage of [[stools]]. | * Acute-onset, foul-smelling watery [[diarrhea]] with or without pus. Diarrhea may occasionally be [[Bloody diarrhea|bloody]]. Diarrhea may be relieved by passage of [[stools]]. | ||
* Crampy, diffuse/lower [[abdominal pain]] | * Crampy, diffuse/lower [[abdominal pain]] | ||
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* [[Weight loss]] | * [[Weight loss]] | ||
=== Alarming | === Alarming Symptoms Suggestive of Colonic Complications === | ||
Patients with ''C. difficile'' infection may have a complicated clinical course due to either colonic or extracolonic complications. Common colonic complications include pseudomembranous colitis and toxic megacolon. The following list of symptoms demonstrates the alarming symptoms that may be suggestive of colonic complications of ''C. difficile'' infection: | Patients with ''C. difficile'' infection may have a complicated clinical course due to either colonic or extracolonic complications. Common colonic complications include pseudomembranous colitis and toxic megacolon. The following list of symptoms demonstrates the alarming symptoms that may be suggestive of colonic complications of ''C. difficile'' infection: | ||
* Worsening diffuse/lower [[abdominal pain]] | * Worsening diffuse/lower [[abdominal pain]] | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Bacterial diseases]] | [[Category:Bacterial diseases]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 17:26, 18 September 2017
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C. difficile Infection Microchapters |
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Differentiating Clostridium difficile infectionfrom other Diseases |
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Diagnosis |
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Treatment |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.
Overview
Clinical manifestations may range from an asymptomatic course to a severe/fatal presentation. Common symptoms include acute-onset, foul-smelling watery diarrhea, crampy diffuse or lower abdominal pain, low-grade fever, malaise, anorexia, nausea, and weight loss. Alarming symptoms that may be suggestive of colonic complications of C. difficile infection include worsening abdominal pain and diarrhea, high-grade fever, dry mucus membranes, and peripheral edema.
History and Symptoms
Clinical manifestations may range from an asymptomatic course to a severe/fatal presentation.
Common Symptoms
- Acute-onset, foul-smelling watery diarrhea with or without pus. Diarrhea may occasionally be bloody. Diarrhea may be relieved by passage of stools.
- Crampy, diffuse/lower abdominal pain
- Low-grade fever
- Malaise
- Anorexia
- Nausea
- Weight loss
Alarming Symptoms Suggestive of Colonic Complications
Patients with C. difficile infection may have a complicated clinical course due to either colonic or extracolonic complications. Common colonic complications include pseudomembranous colitis and toxic megacolon. The following list of symptoms demonstrates the alarming symptoms that may be suggestive of colonic complications of C. difficile infection:
- Worsening diffuse/lower abdominal pain
- Foul smelling, watery diarrhea with or without pus or blood. Diarrhea may be relieved by passage of stools.
- High-grade fever
- Dry mouth and mucus membranes due to dehydration
- Peripheral edema due to hypoalbuminemia
- Delirium
- Coma