Clostridium difficile infection other imaging findings: Difference between revisions

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Latest revision as of 17:26, 18 September 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.

Overview

In patients with suspected C. difficile infection and inconclusive laboratory diagnostic findings, atypical presentation, or unsuccessful antimicrobial therapy, either a sigmoidoscopy or colonoscopy is indicated. During endoscopy, multiple biopsies should be obtained for microscopic histopathological analysis. On gross examination, colonic pseudomembranes with yellow colored plaque formation are typical findings.

Other Imaging Findings

In patients with suspected C. difficile infection and inconclusive laboratory diagnostic findings, atypical presentation, or unsuccessful antimicrobial therapy, either a sigmoidoscopy or colonoscopy is indicated. During endoscopy, multiple biopsies should be obtained for microscopic histopathological analysis.

Gross Endoscopy Findings

The following findings on endoscopy (either sigmoidoscopy or colonoscopy) are suggestive of C. difficile infection:

Colonic pseudomembranes with yellow colored plaque formation
Areas of hemorrhage, which may be either multifocal, segmental, or diffuse
Hyperemic congestion
Marked edema formation of the intestinal wall
Superficial erosions and ulcer formation

For more details about the biopsy findings of C. difficile infection, click here

References

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 __NOTOC__
-{{Clostridium difficile}}
+{{Siren|Clostridium difficile infection}}
-{{CMG}}
+{{Clostridium difficile infection}}
+{{CMG}}; {{AE}} {{YD}}
-Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
+==Overview==
+In patients with suspected ''C. difficile'' infection and inconclusive laboratory diagnostic findings, atypical presentation, or unsuccessful antimicrobial therapy, either a sigmoidoscopy or colonoscopy is indicated. During endoscopy, multiple biopsies should be obtained for microscopic histopathological analysis. On gross examination, colonic pseudomembranes with yellow colored plaque formation are typical findings.
 ==Other Imaging Findings==
-===Sigmoidoscopy===
+In patients with suspected ''C. difficile'' infection and inconclusive laboratory diagnostic findings, atypical presentation, or unsuccessful antimicrobial therapy, either a sigmoidoscopy or colonoscopy is indicated. During endoscopy, multiple biopsies should be obtained for microscopic histopathological analysis.
-Antibiotic-associated diarrhea with ''C. diff'' infection with colitis but without pseudomembrane development may present as:
-* [[Sigmoidoscopy]] shows a nonspecific diffuse or patchy erthrematous [[colitis]] without pseudomembranes.
-Antibiotic-associated diarrhea with ''C. diff'' infection with colitis and pseudomembrane development presents with prominent signs and symptoms as described above and sometimes:
+===Gross Endoscopy Findings===
-* [[Sigmoidoscopy]] shows pseudomembranes; raised yellow or off-white plaques ranging up to 1 cm in diameter scattered over the colorectal mucosa. Occasionally pseudomembranes will be located in the proximal colon.
+The following findings on endoscopy (either sigmoidoscopy or colonoscopy) are suggestive of ''C. difficile'' infection:
+*Colonic pseudomembranes with yellow colored plaque formation
+*Areas of hemorrhage, which may be either multifocal, segmental, or diffuse
+*Hyperemic congestion
+*Marked edema formation of the intestinal wall
+*Superficial erosions and ulcer formation
+<br>'''For more details about the biopsy findings of ''C. difficile'' infection, click [[Clostridium difficile other diagnostic studies|here]]'''
 ==References==
 {{Reflist|2}}
-[[Category:Needs content]]
 [[Category:Disease]]
 [[Category:Gastroenterology]]
-[[Category:Infectious disease]]
 [[Category:Bacterial diseases]]
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 {{WS}}