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==What causes Donovanosis?==
==What causes Donovanosis?==
Donovanosis (granuloma inguinale) is caused by the bacteria Klebsiellagranulomatis. The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea. However, it can sometimes occur in the United States, typically in the Southeast. There are about 100 cases reported per year in the United States.
Donovanosis (granuloma inguinale) is caused by the bacteria [[Klebsiella]] granulomatis. The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea. However, it can sometimes occur in the United States, typically in the Southeast. There are about 100 cases reported per year in the United States.
The disease spreads mostly through vaginal or anal intercourse. Very rarely, it spreads during oral sex.
The disease spreads mostly through vaginal or anal intercourse. Very rarely, it spreads during oral sex.


Men are affected more than twice as often as women. Most infections occur in people ages 20-40. The disease is rarely seen in children or the elderly.
Men are affected more than twice as often as women. Most infections occur in people ages 20-40. The disease is rarely seen in children or the elderly.
==When to seek urgent medical care?==
==When to seek urgent medical care?==
Call for an appointment with your health care provider if:
Call for an appointment with your health care provider if:
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You develop symptoms of donovanosis
You develop symptoms of donovanosis
==Diagnosis==
==Diagnosis==
It may be donovanosis if genital sores have been present for a long time and have been spreading.
It may be donovanosis if [[genital sore]]s have been present for a long time and have been spreading.
Tests that may be done include:
Tests that may be done include:
* Culture of tissue sample (hard to do and not routinely available)
* Culture of tissue sample (hard to do and not routinely available)
* Scrapings or punch biopsy of lesion
* Scrapings or [[punch biopsy]] of lesion
Laboratory tests, such as those used to detect syphilis, are available only on a research basis for diagnosing donovanosis.
Laboratory tests, such as those used to detect [[syphilis]], are available only on a research basis for diagnosing donovanosis.
 
==Treatment options==
==Treatment options==
Antibiotics are used to treat donovanosis. To cure the condition requires long-term treatment. Most treatment courses run 3 weeks or until the sores have completely healed.
[[Antibiotics]] are used to treat donovanosis. To cure the condition requires long-term treatment. Most treatment courses run 3 weeks or until the sores have completely healed.
A follow-up examination is important because the disease can reappear after it seems to be cured.
A follow-up examination is important because the disease can reappear after it seems to be cured.
==Where to find medical care for Donovanosis?==
==Where to find medical care for Donovanosis?==


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==Prevention==
==Prevention==
Avoiding all sexual activity is the only absolute way to prevent a sexually transmitted disease such as donovanosis. However, safer sex behaviors may reduce your risk.
Avoiding all sexual activity is the only absolute way to prevent a sexually transmitted disease such as donovanosis. However, safer sex behaviors may reduce your risk.
The proper use of condoms, either the male or female type, greatly decreases the risk of catching a sexually transmitted disease. You need to wear the condom from the beginning to the end of each sexual activity.
The proper use of [[condom]]s, either the male or female type, greatly decreases the risk of catching a [[sexually transmitted disease]]. You need to wear the condom from the beginning to the end of each sexual activity.
 
==Sources==
==Sources==
http://www.nlm.nih.gov/medlineplus/ency/article/000636.htm
http://www.nlm.nih.gov/medlineplus/ency/article/000636.htm


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[[Category: Infectious disease patient information]]
[[Category:Sexually transmitted infections]]
[[Category:Bacterial diseases]]
 
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Latest revision as of 17:36, 18 September 2017

Donovanosis

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for Donovanosis?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

Donovanosis On the Web

Ongoing Trials at Clinical Trials.gov

Images of Donovanosis

Videos on Donovanosis

FDA on Donovanosis

CDC on Donovanosis

Donovanosis in the news

Blogs on Donovanosis

Directions to Hospitals Treating Donovanosis

Risk calculators and risk factors for Donovanosis

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

Overview

Donovanosis (granuloma inguinale) is a sexually transmitted disease that is rarely seen in the United States.

What are the symptoms of Donovanosis?

  • Symptoms can occur 1 to 12 weeks after coming in contact with the bacteria that cause the disease.
  • About half of infected men and women have sores in the anal area.
  • Small, beefy-red bumps appear on the genitals or around the anus.
  • The skin gradually wears away, and the bumps turn into raised, beefy-red, velvety nodules called granulation tissue. They are usually painless, but they bleed easily if injured.
  • The disease slowly spreads and destroys genital tissue.
  • Tissue damage may spread to the area where the legs meet the torso. This area is called the inguinal folds.
  • The genitals and the skin around them lose skin color.
  • In its early stages, it may be hard to tell the difference between donovanosis and chancroid.
  • In the later stages, donovanosis may look like advanced genital cancers, lymphogranuloma venereum, and anogenital cutaneous amebiasis.

What causes Donovanosis?

Donovanosis (granuloma inguinale) is caused by the bacteria Klebsiella granulomatis. The disease is commonly found in tropical and subtropical areas such as Southeast India, Guyana, and New Guinea. However, it can sometimes occur in the United States, typically in the Southeast. There are about 100 cases reported per year in the United States. The disease spreads mostly through vaginal or anal intercourse. Very rarely, it spreads during oral sex.

Men are affected more than twice as often as women. Most infections occur in people ages 20-40. The disease is rarely seen in children or the elderly.

When to seek urgent medical care?

Call for an appointment with your health care provider if: You have had sexual contact with a person who is known to have donovanosis You develop symptoms of donovanosis

Diagnosis

It may be donovanosis if genital sores have been present for a long time and have been spreading. Tests that may be done include:

  • Culture of tissue sample (hard to do and not routinely available)
  • Scrapings or punch biopsy of lesion

Laboratory tests, such as those used to detect syphilis, are available only on a research basis for diagnosing donovanosis.

Treatment options

Antibiotics are used to treat donovanosis. To cure the condition requires long-term treatment. Most treatment courses run 3 weeks or until the sores have completely healed. A follow-up examination is important because the disease can reappear after it seems to be cured.

Where to find medical care for Donovanosis?

Directions to Hospitals Treating Donovanosis

What to expect (Outlook/Prognosis)?

Treating this disease early decreases the chances of tissue damage or scarring. Untreated disease leads to damage of the genital tissue.

Possible complications

  • Genital damage and scarring
  • Loss of skin color in genital area
  • Permanent genital swelling due to scarring

Prevention

Avoiding all sexual activity is the only absolute way to prevent a sexually transmitted disease such as donovanosis. However, safer sex behaviors may reduce your risk. The proper use of condoms, either the male or female type, greatly decreases the risk of catching a sexually transmitted disease. You need to wear the condom from the beginning to the end of each sexual activity.

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/000636.htm


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