Fifth disease (patient information): Difference between revisions

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{{Fifth disease (patient information)}}
'''For the WikiDoc page for this topic, click [[Fifth disease|here]]'''
'''For the WikiDoc page for this topic, click [[Fifth disease|here]]'''
{{SI}}
 
{{CMG}}; '''Assistant Editor(s)-in-Chief:''' Ethan Leeman
{{CMG}}; '''Assistant Editor(s)-in-Chief:''' Ethan Leeman


==What is Fifth disease?==
==Overview==
'''Fifth disease''', sometimes called '''Erythema infectiosum''', is a mild rash illness caused by a viral infection that occurs most commonly in children. The ill child typically has a "slapped-cheek" rash on the face and a lacy red rash on the trunk and limbs. Occasionally, the rash may itch. An ill child may have a low-grade fever, malaise, or a "cold" a few days before the rash breaks out. The child is usually not very ill, and the rash resolves in 7 to 10 days.
'''Fifth disease''', sometimes called '''Erythema infectiosum''', is a mild rash illness caused by a viral infection that occurs most commonly in children. The ill child typically has a "slapped-cheek" rash on the face and a lacy red rash on the trunk and limbs. Occasionally, the rash may itch. An ill child may have a low-grade fever, malaise, or a "cold" a few days before the rash breaks out. The child is usually not very ill, and the rash resolves in 7 to 10 days.


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*Cold symptoms
*Cold symptoms


[[Image:Erythema_Infectiosum_(FIfths,_ParvoB19).jpg‎|thumb|180px|Child with rosy cheeks and rash characteristic of Fifth disease]]
[[Image:Erythema_Infectiosum_(FIfths,_ParvoB19).jpg‎|thumb|left|180px|Child with rosy cheeks and rash characteristic of Fifth disease]]
 
==Who is at highest risk?==
Anyone can get Fifth disease. Once anyone has had it, they become immunized against the virus. Because the virus is so common, most people acquire immunity in childhood.
 
The disease is not very serious unless the person infected has conditions (problems with immune system, pregnancy, sickle-cell disease, anemia)
 
===Diagnosis===
A physician can often diagnose fifth disease by seeing the typical rash during a physical examination. In cases in which it is important to confirm the diagnosis, a blood test may be done to look for antibodies to parvovirus. Antibodies are proteins produced by the immune system in response to parvovirus B19 and other germs. If immunoglobulin M (IgM) antibody to parvovirus B19 is detected, the test result suggests that the person has had a recent infection.


==What causes Fifth disease?==
==What causes Fifth disease?==
Fifth disease is caused by infection with human parvovirus B19. This virus infects only humans. Parvovirus B19 has been found in the respiratory secretions (e.g., saliva, sputum, or nasal mucus) of infected persons before the onset of rash, when they appear to "just have a cold." The virus is probably spread from person to person by direct contact with those secretions, such as sharing drinking cups or utensils. A person infected with parvovirus B19 is contagious during the early part of the illness, before the rash appears. By the time a child has the characteristic "slapped cheek" rash of fifth disease, for example, he or she is probably no longer contagious and may return to school or child care center. This contagious period is different than that for many other rash illnesses, such as measles, for which the child is contagious while he or she has the rash.
Fifth disease is caused by infection with human parvovirus B19. This virus infects only humans. Parvovirus B19 has been found in the respiratory secretions (e.g., saliva, sputum, or nasal mucus) of infected persons before the onset of rash, when they appear to "just have a cold." The virus is probably spread from person to person by direct contact with those secretions, such as sharing drinking cups or utensils. A person infected with parvovirus B19 is contagious during the early part of the illness, before the rash appears. By the time a child has the characteristic "slapped cheek" rash of fifth disease, for example, he or she is probably no longer contagious and may return to school or child care center. This contagious period is different than that for many other rash illnesses, such as measles, for which the child is contagious while he or she has the rash.
==Who is at highest risk?==
Anyone can get Fifth disease. Once anyone has had it, they become immunized against the virus. Because the virus is so common, most people acquire immunity in childhood. The disease is not very serious unless the person infected has conditions (problems with immune system, pregnancy, sickle-cell disease, anemia)


==When to seek urgent medical care?==
==When to seek urgent medical care?==
Fifth disease is usually a mild illness that resolves on its own among children and adults who are otherwise healthy. Joint pain and swelling in adults usually resolve without long-term disability.
Fifth disease is usually a mild illness that resolves on its own among children and adults who are otherwise healthy. Joint pain and swelling in adults usually resolve without long-term disability.
Parvovirus B19 infection may cause a serious illness in persons with sickle-cell disease or similar types of chronic anemia. In such persons, parvovirus B19 can cause an acute, severe anemia. The ill person may be pale, weak, and tired, and should see his or her physician for treatment. (The typical rash of fifth disease is rarely seen in these persons.) Once the infection is controlled, the anemia resolves. Furthermore, persons who have problems with their immune systems may also develop a chronic anemia with parvovirus B19 infection that requires medical treatment. People who have leukemia or cancer, who are born with immune deficiencies, who have received an organ transplant, or who have human immunodeficiency virus (HIV) infection are at risk for serious illness due to parvovirus B19 infection. Occasionally, serious complications may develop from parvovirus B19 infection during pregnancy. Hydrops fetalis may occur, causing spontaneous abortion.


Parvovirus B19 infection may cause a serious illness in persons with sickle-cell disease or similar types of chronic anemia. In such persons, parvovirus B19 can cause an acute, severe anemia. The ill person may be pale, weak, and tired, and should see his or her physician for treatment. (The typical rash of fifth disease is rarely seen in these persons.) Once the infection is controlled, the anemia resolves. Furthermore, persons who have problems with their immune systems may also develop a chronic anemia with parvovirus B19 infection that requires medical treatment. People who have leukemia or cancer, who are born with immune deficiencies, who have received an organ transplant, or who have human immunodeficiency virus (HIV) infection are at risk for serious illness due to parvovirus B19 infection.
==Diagnosis==
 
A physician can often diagnose fifth disease by seeing the typical rash during a physical examination. In cases in which it is important to confirm the diagnosis, a blood test may be done to look for antibodies to parvovirus. Antibodies are proteins produced by the immune system in response to parvovirus B19 and other germs. If immunoglobulin M (IgM) antibody to parvovirus B19 is detected, the test result suggests that the person has had a recent infection.
Occasionally, serious complications may develop from parvovirus B19 infection during pregnancy. Hydrops fetalis may occur, causing spontaneous abortion.


==Treatment options==
==Treatment options==
Treatment of symptoms such as fever, pain, or itching is usually all that is needed for fifth disease. Adults with joint pain and swelling may need to rest, restrict their activities, and take medicines such as aspirin or ibuprofen to relieve symptoms. The few people who have severe anemia caused by parvovirus B19 infection may need to be hospitalized and receive blood transfusions. Persons with immune problems may need special medical care, including treatment with immune globulin (antibodies), to help their bodies get rid of the infection.
Treatment of symptoms such as fever, pain, or itching is usually all that is needed for fifth disease. Adults with joint pain and swelling may need to rest, restrict their activities, and take medicines such as aspirin or ibuprofen to relieve symptoms. The few people who have severe anemia caused by parvovirus B19 infection may need to be hospitalized and receive blood transfusions. Persons with immune problems may need special medical care, including treatment with immune globulin (antibodies), to help their bodies get rid of the infection.


==Where to find medical care for Fifth disease==
==Where to find medical care for Fifth disease?==
[http://maps.google.com/maps?f=q&hl=en&geocode=&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|Fifth disease}}}}&sll=37.0625,-95.677068&sspn=65.008093,112.148438&ie=UTF8&ll=37.0625,-95.677068&spn=91.690419,149.414063&z=2&source=embed Directions to Hospitals Treating Fifth disease]
[http://maps.google.com/maps?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|map+top+hospital+Fifth disease}}}}&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&ie=UTF-8&sa=N&hl=en&tab=wl Directions to Hospitals Treating Fifth disease]
 
==What to expect (Outlook/Prognosis)?==
Patient generally recover fully from the illness.
 
==Possible complications==
There are generally no complications in normally healthy children.


==Prevention of Fifth disease==
==Prevention of Fifth disease==
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*[http://www.cdc.gov/ncidod/dvrd/revb/respiratory/parvo_b19.htm CDC]
*[http://www.cdc.gov/ncidod/dvrd/revb/respiratory/parvo_b19.htm CDC]


==References==
{{WS}}
{{reflist}}
{{WH}}
{{SIB}}


[[Category:Patient information]]
[[Category:Patient information]]
[[Category:Pediatrics]]
[[Category:Pediatrics]]
[[Category:Pediatrics patient information]]
[[Category:Disease state]]
[[Category:Viral diseases]]
[[Category:Viral diseases]]
[[Category:Mature chapter]]
[[Category:Disease]]
 
{{WH}} {{WS}}

Latest revision as of 17:44, 18 September 2017

Fifth disease

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

When to seek urgent medical care?

Diagnosis

Treatment options

Where to find medical care for Fifth disease?

What to expect (Outlook/Prognosis)?

Possible complications

Prevention

Fifth disease On the Web

Ongoing Trials at Clinical Trials.gov

Images of Fifth disease

Videos on Fifth disease

FDA on Fifth disease

CDC on Fifth disease

Fifth disease in the news

Blogs on Fifth disease

Directions to Hospitals Treating Fifth disease

Risk calculators and risk factors for Fifth disease

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-in-Chief: Ethan Leeman

Overview

Fifth disease, sometimes called Erythema infectiosum, is a mild rash illness caused by a viral infection that occurs most commonly in children. The ill child typically has a "slapped-cheek" rash on the face and a lacy red rash on the trunk and limbs. Occasionally, the rash may itch. An ill child may have a low-grade fever, malaise, or a "cold" a few days before the rash breaks out. The child is usually not very ill, and the rash resolves in 7 to 10 days.

What are the symptoms of Fifth disease?

  • Characteristic red cheeks
  • Red, lacy rash, often found on arms and legs
  • Arthritis in older patients, sometimes causing trouble walking
  • Low fever
  • Cold symptoms
Child with rosy cheeks and rash characteristic of Fifth disease

What causes Fifth disease?

Fifth disease is caused by infection with human parvovirus B19. This virus infects only humans. Parvovirus B19 has been found in the respiratory secretions (e.g., saliva, sputum, or nasal mucus) of infected persons before the onset of rash, when they appear to "just have a cold." The virus is probably spread from person to person by direct contact with those secretions, such as sharing drinking cups or utensils. A person infected with parvovirus B19 is contagious during the early part of the illness, before the rash appears. By the time a child has the characteristic "slapped cheek" rash of fifth disease, for example, he or she is probably no longer contagious and may return to school or child care center. This contagious period is different than that for many other rash illnesses, such as measles, for which the child is contagious while he or she has the rash.

Who is at highest risk?

Anyone can get Fifth disease. Once anyone has had it, they become immunized against the virus. Because the virus is so common, most people acquire immunity in childhood. The disease is not very serious unless the person infected has conditions (problems with immune system, pregnancy, sickle-cell disease, anemia)

When to seek urgent medical care?

Fifth disease is usually a mild illness that resolves on its own among children and adults who are otherwise healthy. Joint pain and swelling in adults usually resolve without long-term disability. Parvovirus B19 infection may cause a serious illness in persons with sickle-cell disease or similar types of chronic anemia. In such persons, parvovirus B19 can cause an acute, severe anemia. The ill person may be pale, weak, and tired, and should see his or her physician for treatment. (The typical rash of fifth disease is rarely seen in these persons.) Once the infection is controlled, the anemia resolves. Furthermore, persons who have problems with their immune systems may also develop a chronic anemia with parvovirus B19 infection that requires medical treatment. People who have leukemia or cancer, who are born with immune deficiencies, who have received an organ transplant, or who have human immunodeficiency virus (HIV) infection are at risk for serious illness due to parvovirus B19 infection. Occasionally, serious complications may develop from parvovirus B19 infection during pregnancy. Hydrops fetalis may occur, causing spontaneous abortion.

Diagnosis

A physician can often diagnose fifth disease by seeing the typical rash during a physical examination. In cases in which it is important to confirm the diagnosis, a blood test may be done to look for antibodies to parvovirus. Antibodies are proteins produced by the immune system in response to parvovirus B19 and other germs. If immunoglobulin M (IgM) antibody to parvovirus B19 is detected, the test result suggests that the person has had a recent infection.

Treatment options

Treatment of symptoms such as fever, pain, or itching is usually all that is needed for fifth disease. Adults with joint pain and swelling may need to rest, restrict their activities, and take medicines such as aspirin or ibuprofen to relieve symptoms. The few people who have severe anemia caused by parvovirus B19 infection may need to be hospitalized and receive blood transfusions. Persons with immune problems may need special medical care, including treatment with immune globulin (antibodies), to help their bodies get rid of the infection.

Where to find medical care for Fifth disease?

Directions to Hospitals Treating Fifth disease

What to expect (Outlook/Prognosis)?

Patient generally recover fully from the illness.

Possible complications

There are generally no complications in normally healthy children.

Prevention of Fifth disease

There is no vaccine or medicine that prevents parvovirus B19 infection. Frequent handwashing is recommended as a practical and probably effective method to decrease the chance of becoming infected. Excluding persons with fifth disease from work, child care centers, or schools is not likely to prevent the spread of the virus, since people are contagious before they develop the rash.

Sources

Template:WS Template:WH