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==Overview==
==Overview==


Balamuthia mandrillaris has only recently been isolated from the environment and has also been isolated from autopsy specimens of infected humans and animals. B. mandrillaris has only two stages, cysts and trophozoites , in its life cycle. No flagellated stage exists as part of the life   cycle. The trophozoites replicate by mitosis (nuclear membrane does not remain intact) . The trophozoites are the infective forms, although both cysts and   trophozoites gain entry into the body  through various means. Entry can occur through the nasal passages to   the lower respiratory tract , or ulcerated or broken skin . When B. mandrillaris enters the respiratory system or   through the skin, it can invade the central nervous system by hematogenous   dissemination causing granulomatous amebic encephalitis (GAE)  or disseminated disease , or skin lesions  in individuals who are immune competent as well as those with   compromised immune systems. B. mandrillaris cysts and trophozoites are   found in tissue.
Balamuthia mandrillaris has only recently been isolated from the environment and has also been isolated from autopsy specimens of infected humans and animals. B. mandrillaris has only two stages, [[cyst]]s and [[trophozoites]] , in its life cycle. No flagellated stage exists as part of the life cycle. The [[trophozoites]] replicate by [[mitosis]] (nuclear membrane does not remain intact) . The trophozoites are the infective forms, although both [[cyst]]s and [[trophozoites]] gain entry into the body  through various means. Entry can occur through the nasal passages to the lower respiratory tract , or ulcerated or broken skin . When B. mandrillaris enters the respiratory system or through the [[skin]], it can invade the [[central nervous system]] by hematogenous dissemination causing [[granulomatous amebic encephalitis]] (GAE)  or disseminated disease , or skin lesions  in individuals who are immune competent as well as those with compromised immune systems. B. mandrillaris [[cyst]]s and [[trophozoites]] are found in tissue.


==References==
==References==
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[[Category:Neurology]]
[[Category:Neurology]]
[[Category:Infectious disease]]
 


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Latest revision as of 17:50, 18 September 2017

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Overview

Balamuthia mandrillaris has only recently been isolated from the environment and has also been isolated from autopsy specimens of infected humans and animals. B. mandrillaris has only two stages, cysts and trophozoites , in its life cycle. No flagellated stage exists as part of the life cycle. The trophozoites replicate by mitosis (nuclear membrane does not remain intact) . The trophozoites are the infective forms, although both cysts and trophozoites gain entry into the body through various means. Entry can occur through the nasal passages to the lower respiratory tract , or ulcerated or broken skin . When B. mandrillaris enters the respiratory system or through the skin, it can invade the central nervous system by hematogenous dissemination causing granulomatous amebic encephalitis (GAE) or disseminated disease , or skin lesions in individuals who are immune competent as well as those with compromised immune systems. B. mandrillaris cysts and trophozoites are found in tissue.

References


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