Hepatitis D laboratory tests: Difference between revisions
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Varun Kumar (talk | contribs) (Created page with "{{Hepatitis D}} {{CMG}} ==Lab Tests== *Anti-delta agent antibody *Liver biopsy *Liver enzymes (blood test) ==References== {{reflist|2}} D [[Category:...") |
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{{Hepatitis D}} | {{Hepatitis D}} | ||
{{CMG}} | {{CMG}}; {{AOEIC}} {{VK}} | ||
==Lab Tests== | ==Lab Tests== | ||
* | *Detection of HDV RNA using reverse transcriptase polymerase chain reaction assay has a high sensitivity in detection of HDV [[viremia]]. | ||
*Liver | *HDV antigen may be detected. | ||
* | *Levels of anti-delta agent antibodies such as [[IgM]] and [[IgG]] are generally be elevated. Detection of [[IgA]] antibodies to HDV is exclusively associated with chronic HDV infection.<ref name="pmid1959886">{{cite journal |author=McFarlane IG, Chaggar K, Davies SE, Smith HM, Alexander GJ, Williams R |title=IgA class antibodies to hepatitis delta virus antigen in acute and chronic hepatitis delta virus infections |journal=[[Hepatology (Baltimore, Md.)]] |volume=14 |issue=6 |pages=980–4 |year=1991 |month=December |pmid=1959886 |doi= |url= |accessdate=2012-03-16}}</ref> | ||
*Patients may also be positive for [[HBsAg]] and anti-HB core IgM. However HBsAg levels may be suppressed to undetectable levels with active HDV replication. | |||
*Liver function tests may generally show elevated serum [[alanine aminotransferase]] and [[aspartate aminotransferase]] levels. | |||
*Elevated international normalized ratio ([[INR]]) with prolongation of [[prothrombin time]] suggests fulminant [[hepatic failure]]. | |||
==References== | ==References== | ||
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[[Category:Hepatitis|D]] | [[Category:Hepatitis|D]] | ||
[[Category:Viruses]] | [[Category:Viruses]] | ||
[[Category:Disease]] | |||
[[Category:Gastroenterology]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 17:56, 18 September 2017
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Hepatitis D |
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Diagnosis |
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Treatment |
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Hepatitis D laboratory tests On the Web |
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American Roentgen Ray Society Images of Hepatitis D laboratory tests |
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Risk calculators and risk factors for Hepatitis D laboratory tests |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]
Lab Tests
- Detection of HDV RNA using reverse transcriptase polymerase chain reaction assay has a high sensitivity in detection of HDV viremia.
- HDV antigen may be detected.
- Levels of anti-delta agent antibodies such as IgM and IgG are generally be elevated. Detection of IgA antibodies to HDV is exclusively associated with chronic HDV infection.[1]
- Patients may also be positive for HBsAg and anti-HB core IgM. However HBsAg levels may be suppressed to undetectable levels with active HDV replication.
- Liver function tests may generally show elevated serum alanine aminotransferase and aspartate aminotransferase levels.
- Elevated international normalized ratio (INR) with prolongation of prothrombin time suggests fulminant hepatic failure.
References
- ↑ McFarlane IG, Chaggar K, Davies SE, Smith HM, Alexander GJ, Williams R (1991). "IgA class antibodies to hepatitis delta virus antigen in acute and chronic hepatitis delta virus infections". Hepatology (Baltimore, Md.). 14 (6): 980–4. PMID 1959886. Unknown parameter
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