HIV coinfection with hepatitis c: Difference between revisions

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{{Hepatitis C}}
__NOTOC__
{{HIV coinfection with hepatitis c}}
'''For main chapter on AIDS, click [[AIDS|here]]'''
 
'''For main chapter on HIV, click [[HIV|here]]'''
'''For main chapter on Hepatitis C, click [[Hepatitis C|here]]'''
 
{{CMG}}; {{AOEIC}} {{VK}}
{{CMG}}; {{AOEIC}} {{VK}}
==Overview==
In HIV–HCV co-infected patients, the Hepatitis C (HCV) viral load is higher than in HCV-mono-infected patients in both the plasma and liver tissue.


==Cause of Co-infection==
==[[HIV coinfection with hepatitis c overview|Overview]]==
Patients who are HIV-positive are commonly co-infected with HCV due to the following:
 
*Shared routes of transmission.
==[[HIV coinfection with hepatitis c pathophysiology|Pathophysiology]]==
*Percutaneous exposure to blood.
 
*Sexual intercourse.
==[[HIV coinfection with hepatitis c causes|Causes]]==
*From a mother to her infant.
 
==[[HIV coinfection with hepatitis c differential diagnosis|Differentiating HIV coinfection with hepatitis c from other Diseases]]==


==Recommendations for Diagnosis and Treatment of Persons with HIV Coinfection: AASLD Practice Guidelines 2009<ref name="pmid19554546">{{cite journal |author=Swan T, Curry J |title=Comment on the updated AASLD practice guidelines for the diagnosis, management, and treatment of hepatitis C: treating active drug users |journal=[[Hepatology (Baltimore, Md.)]] |volume=50 |issue=1 |pages=323–4; author reply 324–5 |year=2009 |month=July |pmid=19554546 |doi=10.1002/hep.23077 |url=http://dx.doi.org/10.1002/hep.23077 |accessdate=2012-02-21}}</ref>==
==[[HIV coinfection with hepatitis c epidemiology and demographics|Epidemiology and Demographics]]==
{{cquote|
'''1.''' Anti-HCV testing should be performed in all HIV-infected persons ''(Class I, Level B)''.


'''2.''' HCV RNA testing should be performed to confirm HCV infection in HIV-infected persons who are positive for anti-HCV, as well as in those who are negative and have evidence of unexplained liver disease ''(Class I, Level B)''.
==[[HIV coinfection with hepatitis c risk factors|Risk Factors]]==


'''3.''' Hepatitis C should be treated in the HIV/HCV co-infected patient in whom the likelihood of serious liver disease and a treatment response are judged to outweigh the risk of morbidity from the adverse effects of therapy ''(Class I, Level A)''.
==[[HIV coinfection with hepatitis c natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


'''4.''' Initial treatment of hepatitis C in most HIV infected patients should be peginterferon alfa plus ribavirin for 48 weeks at doses recommended for HCV mono-infected patients  ''(Class I, Level A)''.
==Diagnosis==


'''5.''' When possible, patients receiving [[zidovudine]] (AZT) and especially didanosine (ddI) should be switched to an equivalent antiretroviral agent before beginning therapy with ribavirin ''(Class I, Level C)''.
[[HIV coinfection with hepatitis c history and symptoms|History and Symptoms]] | [[HIV coinfection with hepatitis c physical examination|Physical Examination]] | [[HIV coinfection with hepatitis c laboratory findings|Laboratory Findings]]


'''6.''' HIV-infected patients with decompensated liver disease (CTP Class B or C) should not be treated with peginterferon alfa and ribavirin and may be candidates for liver transplantation ''(Class IIa, Level C)''.}}
==Treatment==


==References==
[[HIV coinfection with hepatitis c medical therapy|Medical Therapy]] | [[HIV coinfection with hepatitis c prevention|Prevention]] | [[HIV coinfection with hepatitis c cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[HIV coinfection with hepatitis c future or investigational therapies|Future or Investigational Therapies]]
{{reflist|2}}


{{WS}}
==Case Studies==
{{WH}}
[[HIV coinfection with hepatitis c case study one|Case #1]]


[[Category:Hepatitis|C]]
==Related Chapters==
[[Category:Gastroenterology]]
[[Category:Infectious disease]]
[[Category:Disease]]


==References==
* [[Coinfection]]
{{reflist|2}}
* [[AIDS]]
* [[HIV disease]]
* [[Hepatitis B with HIV coinfection]]
* [[Tuberculosis and HIV coinfection]]
* [[HIV and tuberculosis coinfection : drug interaction]]
* [[HIV and pregnancy]]
* [[Hepatitis]]


{{WS}}
{{WS}}
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[[Category:Hepatitis|C]]
[[Category:Hepatitis|C]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Infectious disease]]
 
[[Category:Disease]]
[[Category:Disease]]

Latest revision as of 18:01, 18 September 2017

HIV coinfection with hepatitis c Microchapters

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Overview

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Treatment

Medical Therapy

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Case #1

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For main chapter on AIDS, click here

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]

Overview

Pathophysiology

Causes

Differentiating HIV coinfection with hepatitis c from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings

Treatment

Medical Therapy | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Related Chapters

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