Isosporiasis pathophysiology: Difference between revisions
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== Pathophysiology== | == Pathophysiology== | ||
===Life Cycle=== | |||
[[Image:Isospora_LifeCycle.gif| | * At time of excretion, the immature oocyst contains usually one sporoblast (more rarely two) '''1'''. | ||
* In further maturation after excretion, the sporoblast divides in two (the oocyst now contains two sporoblasts); the sporoblasts secrete a cyst wall, thus becoming sporocysts; and the sporocysts divide twice to produce four sporozoites each '''2'''. | |||
* Infection occurs by ingestion of sporocysts-containing oocysts: the sporocysts excyst in the small intestine and release their sporozoites, which invade the epithelial cells and initiate schizogony '''3'''. | |||
* Upon rupture of the schizonts, the merozoites are released, invade new epithelial cells, and continue the cycle of asexual multiplication '''4'''. Trophozoites develop into schizonts which contain multiple merozoites. | |||
* After a minimum of one week, the sexual stage begins with the development of male and female gametocytes '''5'''. | |||
* Fertilization results in the development of oocysts that are excreted in the stool '''1'''. Isospora belli infects both humans and animals. | |||
[[Image:Isospora_LifeCycle.gif|center|frame|Life cycle of Isospora belli]] | |||
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==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Parasitic diseases]] | [[Category:Parasitic diseases]] | ||
[[Category:Needs content]] |
Latest revision as of 18:06, 18 September 2017
Isosporiasis Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Isosporiasis pathophysiology On the Web |
American Roentgen Ray Society Images of Isosporiasis pathophysiology |
Risk calculators and risk factors for Isosporiasis pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Pathophysiology
Life Cycle
- At time of excretion, the immature oocyst contains usually one sporoblast (more rarely two) 1.
- In further maturation after excretion, the sporoblast divides in two (the oocyst now contains two sporoblasts); the sporoblasts secrete a cyst wall, thus becoming sporocysts; and the sporocysts divide twice to produce four sporozoites each 2.
- Infection occurs by ingestion of sporocysts-containing oocysts: the sporocysts excyst in the small intestine and release their sporozoites, which invade the epithelial cells and initiate schizogony 3.
- Upon rupture of the schizonts, the merozoites are released, invade new epithelial cells, and continue the cycle of asexual multiplication 4. Trophozoites develop into schizonts which contain multiple merozoites.
- After a minimum of one week, the sexual stage begins with the development of male and female gametocytes 5.
- Fertilization results in the development of oocysts that are excreted in the stool 1. Isospora belli infects both humans and animals.