Lassa fever history and symptoms: Difference between revisions

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{{Lassa fever}}
{{Lassa fever}}
{{CMG}}; {{Ammu}}
{{CMG}}; {{Ammu}}
{{SK}} Lassa hemorrhagic fever; LHF
==Overview==
==Overview==
Lassa fever after an [[incubation period]] of six to twenty-one days, manifest as an acute illness with multiorgan involvement and patients present with [[gastrointestinal]], neurological and [[pulmonary]] symptoms.
Common symptoms of Lassa fever typically include persistent, high-grade [[fever]] and other non-specific symptoms, such as [[headache]], [[myalgia]]/[[arthralgia]], [[cough]], [[conjunctival injection]], and [[vomiting]]. Less commonly, patients may present with more severe symptoms, such as [[GI bleeding]], [[deafness]], [[confusion]], [[seizure]]s, and [[coma]].


==Diagnosis==
==Diagnosis==
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* [[Hearing loss]]
* [[Hearing loss]]
<br>
<br>
The following graph demonstrates the common and rare symptoms associated with Lassa fever:
 
[[File:Signs and symptoms Lassa.png|thumb|left|800 px|Signs and symptoms of Lassa fever<SMALL><SMALL>''[http://www.cdc.gov/NCIDOD/dvrd/spb/mnpages/lassaslides.htm]''</SMALL></SMALL>]]<br>
The following table lists the common symptoms of Lassa fever and their corresponding prevalence among infected patients:
<br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br>
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Symptom of Lassa Fever'''
| align="center" style="background:#f0f0f0;"|'''Prevalence Among Infected Patients (%)'''
|-
| Fever||≈100
|-
| Headache||80-90
|-
| Arthralgia/Myalgia||80-90
|-
| Retrosternal Chest Pain||80-90
|-
| Weakness||70-80
|-
| Dizziness||70-80
|-
| Sore Throat/Pharyngitis||60-80
|-
| Cough||60-70
|-
| Vomiting||60-70
|-
| Abdominal Pain||50-60
|-
| Diarrhea||30-50
|-
| Conjunctivitis/Subconjunctival Hemorrhage||30-40
|-
| Chills||20-40
|-
| Deafness||20-30
|-
| Bleeding||20-30
|-
| Confusion||10-20
|-
| Swollen Neck or Face||10-20
|}
 
==Less Common Symptoms==
==Less Common Symptoms==
Less common symptoms of Lassa fever usually develop late and are often associated with a more severe course of disease.
Less common symptoms of Lassa fever usually develop late and are often associated with a more severe course of disease.
===[[Skin]]===
===Skin===
*Jaundice
*[[Jaundice]]


===HEENT===
===HEENT===
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*[[Confusion]]
*[[Confusion]]
* [[Seizure]]
* [[Seizure]]


==References==
==References==
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[[Category:Tropical disease]]
[[Category:Tropical disease]]
[[Category:Biological weapons]]
[[Category:Biological weapons]]
[[Category:Infectious disease]]
 


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Latest revision as of 18:08, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ammu Susheela, M.D. [2]

Overview

Common symptoms of Lassa fever typically include persistent, high-grade fever and other non-specific symptoms, such as headache, myalgia/arthralgia, cough, conjunctival injection, and vomiting. Less commonly, patients may present with more severe symptoms, such as GI bleeding, deafness, confusion, seizures, and coma.

Diagnosis

The current case definition for suspecting Lassa fever is as follows:[1]

Unexplained fever at least 38 °C or 100.4 °F for ≥ 1 week
And 1 of the following:
▸ No response to standard treatment with the choice of regimen for most likely cause of fever (malaria, typhoid fever)
▸ Readmitted within 3 weeks of inpatient care for an illness with fever
And 1 of the following
▸ Edema or bleeding
▸ Sore throat and retrosternal pain/vomiting
▸ Spontaneous abortion following fever
▸ Hearing loss following fever










Common Symptoms

Common symptoms of Lassa fever are often non-specific symptoms that resemble symptoms of other viral infections:


The following table lists the common symptoms of Lassa fever and their corresponding prevalence among infected patients:

Symptom of Lassa Fever Prevalence Among Infected Patients (%)
Fever ≈100
Headache 80-90
Arthralgia/Myalgia 80-90
Retrosternal Chest Pain 80-90
Weakness 70-80
Dizziness 70-80
Sore Throat/Pharyngitis 60-80
Cough 60-70
Vomiting 60-70
Abdominal Pain 50-60
Diarrhea 30-50
Conjunctivitis/Subconjunctival Hemorrhage 30-40
Chills 20-40
Deafness 20-30
Bleeding 20-30
Confusion 10-20
Swollen Neck or Face 10-20

Less Common Symptoms

Less common symptoms of Lassa fever usually develop late and are often associated with a more severe course of disease.

Skin

HEENT

Gastrointestinal tract

Cardiovascular system

Respiratory tract

Nervous system

References

  1. ↑ "The Centers for Disease Control and Prevention" (PDF).


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