Lassa fever history and symptoms: Difference between revisions
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Latest revision as of 18:08, 18 September 2017
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Lassa fever Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Lassa fever history and symptoms On the Web |
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American Roentgen Ray Society Images of Lassa fever history and symptoms |
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Risk calculators and risk factors for Lassa fever history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ammu Susheela, M.D. [2]
Overview
Common symptoms of Lassa fever typically include persistent, high-grade fever and other non-specific symptoms, such as headache, myalgia/arthralgia, cough, conjunctival injection, and vomiting. Less commonly, patients may present with more severe symptoms, such as GI bleeding, deafness, confusion, seizures, and coma.
Diagnosis
The current case definition for suspecting Lassa fever is as follows:[1]
| Unexplained fever at least 38 °C or 100.4 °F for ≥ 1 week |
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| And 1 of the following: |
| ▸ No response to standard treatment with the choice of regimen for most likely cause of fever (malaria, typhoid fever) |
| ▸ Readmitted within 3 weeks of inpatient care for an illness with fever |
| And 1 of the following |
| ▸ Edema or bleeding |
| ▸ Sore throat and retrosternal pain/vomiting |
| ▸ Spontaneous abortion following fever |
| ▸ Hearing loss following fever |
Common Symptoms
Common symptoms of Lassa fever are often non-specific symptoms that resemble symptoms of other viral infections:
- Fever and chills (typically persistent, high-grade fever)
- Headache
- Malaise
- Myalgia
- Arthralgia
- Chest pain (typically retrosternal)
- Dizziness
- Weakness
- Dizziness
- Sore throat
- Back pain
- Cough
- Nausea and Vomiting
- Abdominal pain
- Diarrhea (may be bloody)
- Conjunctival injection and conjunctival hemorrhage
- Mucosal bleeding
- Hearing loss
The following table lists the common symptoms of Lassa fever and their corresponding prevalence among infected patients:
| Symptom of Lassa Fever | Prevalence Among Infected Patients (%) |
| Fever | ≈100 |
| Headache | 80-90 |
| Arthralgia/Myalgia | 80-90 |
| Retrosternal Chest Pain | 80-90 |
| Weakness | 70-80 |
| Dizziness | 70-80 |
| Sore Throat/Pharyngitis | 60-80 |
| Cough | 60-70 |
| Vomiting | 60-70 |
| Abdominal Pain | 50-60 |
| Diarrhea | 30-50 |
| Conjunctivitis/Subconjunctival Hemorrhage | 30-40 |
| Chills | 20-40 |
| Deafness | 20-30 |
| Bleeding | 20-30 |
| Confusion | 10-20 |
| Swollen Neck or Face | 10-20 |
Less Common Symptoms
Less common symptoms of Lassa fever usually develop late and are often associated with a more severe course of disease.
Skin
HEENT
Gastrointestinal tract
Cardiovascular system
Respiratory tract
Nervous system
References