Lassa fever other diagnostic studies: Difference between revisions
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{{Lassa fever}} | {{Lassa fever}} | ||
{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
Other | Other diagnostic tests to confirm the diagnosis of lassa fever include [[reverse transcription]]-[[polymerase chain reaction]] ([[RT-PCR]]) and [[immunohistochemistry]] using either [[skin]], [[tissue]] or [[liver]] tissue. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
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| align="center" style="background:#4479BA; padding: 5px 5px;"|{{fontcolor|#FFF|'''Detects'''}} | | align="center" style="background:#4479BA; padding: 5px 5px;"|{{fontcolor|#FFF|'''Detects'''}} | ||
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| style="padding: 5px 5px; background: #EBEBEB;"| | | style="padding: 5px 5px; background: #EBEBEB;"| [[Polymerase Chain Reaction]] (PCR)||style="padding: 5px 5px; background: #EBEBEB;"|[[Serum]] or [[plasma]] or [[tissues]] (fresh frozen) ||style="padding: 5px 5px; background: #EBEBEB;"|Freeze or refrigerate||style="padding: 5px 5px; background: #EBEBEB;"|Detects [[DNA]], [[RNA]] (genetic material) from [[virus]]. | ||
|- | |- | ||
| style="padding: 5px 5px; background: #EBEBEB;"| | | style="padding: 5px 5px; background: #EBEBEB;"| [[Immunohistochemistry]]||style="padding: 5px 5px; background: #EBEBEB;"|[[Liver]] biopsy from fatal cases ||style="padding: 5px 5px; background: #EBEBEB;"|Fix in formalin and store or transport in room temperature ||style="padding: 5px 5px; background: #EBEBEB;"|Detects viral [[antigen]] in [[cells]]. | ||
|- | |- | ||
| style="padding: 5px 5px; background: #EBEBEB;"| | | style="padding: 5px 5px; background: #EBEBEB;"| [[Immunohistochemistry]]||style="padding: 5px 5px; background: #EBEBEB;"|[[Tissue]] biopsy from fatal cases ||style="padding: 5px 5px; background: #EBEBEB;"|Fix in formalin and store or transport in room temperature ||style="padding: 5px 5px; background: #EBEBEB;"|Detects viral [[antigen]] in cells | ||
|- | |- | ||
| style="padding: 5px 5px; background: #EBEBEB;"| | | style="padding: 5px 5px; background: #EBEBEB;"| [[Immunohistochemistry]]||style="padding: 5px 5px; background: #EBEBEB;"|[[Skin]] biopsy from fatal cases ||style="padding: 5px 5px; background: #EBEBEB;"|Fix in formalin and store or transport in room temperature ||style="padding: 5px 5px; background: #EBEBEB;"|Detects viral [[antigen]] in cells | ||
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<SMALL>Data from the | <SMALL>Data from the Centers for Disease Control and Prevention</SMALL> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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[[Category:Tropical disease]] | [[Category:Tropical disease]] | ||
[[Category:Biological weapons]] | [[Category:Biological weapons]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Latest revision as of 18:08, 18 September 2017
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Lassa fever Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Lassa fever other diagnostic studies On the Web |
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American Roentgen Ray Society Images of Lassa fever other diagnostic studies |
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Risk calculators and risk factors for Lassa fever other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Other diagnostic tests to confirm the diagnosis of lassa fever include reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry using either skin, tissue or liver tissue.
Other Diagnostic Studies
Listed below are some of the diagnostic test used to confirm Lassa fever.[1]
| Diagnostic Test | Samples required | Preparation & Storage | Detects |
| Polymerase Chain Reaction (PCR) | Serum or plasma or tissues (fresh frozen) | Freeze or refrigerate | Detects DNA, RNA (genetic material) from virus. |
| Immunohistochemistry | Liver biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells. |
| Immunohistochemistry | Tissue biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
| Immunohistochemistry | Skin biopsy from fatal cases | Fix in formalin and store or transport in room temperature | Detects viral antigen in cells |
Data from the Centers for Disease Control and Prevention
References