Lassa fever risk factors: Difference between revisions

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{{Lassa fever}}
{{Lassa fever}}
{{CMG}}; {{AE}} {{Ammu}}
{{CMG}}; {{AE}} {{Ammu}}
==Overview==
Individuals at risk are those who live or visit areas with a high population of Mastomys rodents infected with Lassa virus or are exposed to infected humans. Hospital staff are not at great risk for infection as long as protective measures are taken.
==Risk Factors in the Development of Lassa Fever==
The following are considered risk factors for developing Lassa fever:
*Travel to endemic region (West Africa)
*Exposure to infected individuals
*Exposure to rodents (Mastomys natalensis rat/mouse) or contaminated household items (including food)
*Occupational exposure in healthcare settings
==Risk Factors in the Development of Lassa Fever-Associated Complications and Death==
*Young age
*[[Pregnancy]] (especially 3rd trimester)
*[[Immunosuppression]]


{{SK}} Lassa hemorrhagic fever; LHF
==Level of Risk Upon Exposure==
==Overview==
Individuals at risk are those who live or visit areas with a high [[population]] of Mastomys rodents infected with Lassa virus or are exposed to infected humans. Hospital staff are not at great risk for [[infection]] as long as protective measures are taken.
==Risk Factors==
* Individuals at greatest risk of Lassa virus infection are those who live in or visit endemic regions, including Sierra Leone, Liberia, Guinea, and Nigeria and have exposure to the multimammate rat.  Risk of exposure may also exist in other west African countries where Mastomys rodents exist. Hospital staff are not at great risk for infection as long as protective measures and proper sterilization methods are used. <ref name=CDC>{{cite web | title = The Centers for Disease Control and Prevention | url =http://www.cdc.gov/vhf/lassa/transmission/index.html }}</ref>
* Individuals at greatest risk of Lassa virus infection are those who live in or visit endemic regions, including Sierra Leone, Liberia, Guinea, and Nigeria and have exposure to the multimammate rat.  Risk of exposure may also exist in other west African countries where Mastomys rodents exist. Hospital staff are not at great risk for infection as long as protective measures and proper sterilization methods are used. <ref name=CDC>{{cite web | title = The Centers for Disease Control and Prevention | url =http://www.cdc.gov/vhf/lassa/transmission/index.html }}</ref>
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
! style="padding: 0 5px; font-size: 100%; background: #4479BA" align=center | ''{{fontcolor|#FFF|Level of risk related to exposure to a patient with Lassa fever}}''
! style="padding: 0 5px; font-size: 100%; background: #4479BA" align=center | ''{{fontcolor|#FFF|Level of risk related to exposure to a patient with Lassa fever}}''
|-
|-
! style="padding: 0 5px; font-size: 95%; background:  #DCDCDC" align=left | '''High risk'''
! style="padding: 0 5px; font-size: 95%; background:  #DCDCDC" align=left | '''<span style="color:red">High Risk</span>'''
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Exposure from a percutaneous injury (i.e. needlestick or cut with a sharp object) to blood tissue or other body fluids that are potentially infectious (e.g: urine, vomitus or stool).
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Exposure from a percutaneous injury (i.e. [[needlestick]] or cut with a sharp object) to [[blood]], [[tissue]] or other [[body fluids]] that are potentially [[infectious]] (e.g: [[urine]], [[vomitus]] or [[stool]]).
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Exposure from direct unprotected contact with potentially infectious material (e.g: touching vomitus with an ungloved hand).
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Exposure from direct unprotected [[contact]] with potentially infectious material (e.g: touching [[vomitus]] with an ungloved [[hand]]).
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Mucosal exposure (eg. of eyes, nose or mouth) to splashes or droplet of potentially infectious blood and body fluid or sexual contact with a symptomatic partner.
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ [[Mucosal]] exposure (eg. of [[eyes]], [[nose]] or [[mouth]]) to splashes or droplet of potentially infectious [[blood]] and [[body fluid]] or [[sexual contact]] with a symptomatic partner.
|-
|-
! style="padding: 0 5px; font-size: 95%; background: #DCDCDC" align=left | '''Low risk'''
! style="padding: 0 5px; font-size: 95%; background: #DCDCDC" align=left | '''<span style="color:red">Low Risk</span>'''
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Sharing a room or sitting in a vehicle within 6 feet (i.e. coughing distance) of a potentially infectious person without direct contact with a potentially infectious material.
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Sharing a room or sitting in a vehicle within 6 feet (i.e. [[coughing distance]]) of a potentially infectious person without [[direct contact]] with a potentially infectious material.
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Providing routine medical care while using personal protective equipment(PPE) appropriately.
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Providing routine medical care while using [[personal protective equipment]] (PPE) appropriately.
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Routine cleaning and laundry of contaminated linens and surfaces while using personal protective equipment(PPE) appropriately.
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Routine cleaning and laundry of contaminated [[linens]] and surfaces while using [[personal protective equipment]] (PPE) appropriately.
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Transport of a potentially infectious patient or specimen without direct contact with potentially infectious material.
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Transport of a potentially infectious patient or specimen without [[direct contact]] with potentially infectious material.
|-
|-
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Handling of clinical specimen while using personal protective equipment(PPE) appropriately.
| rowspan="1" style="font-size: 95%; padding: 0 5px; background: #F5F5F5" | ▸ Handling of clinical specimen while using [[personal protective equipment]] (PPE) appropriately.
|}
|}


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[[Category:Tropical disease]]
[[Category:Tropical disease]]
[[Category:Biological weapons]]
[[Category:Biological weapons]]
[[Category:Infectious disease]]
 


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Latest revision as of 18:09, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Individuals at risk are those who live or visit areas with a high population of Mastomys rodents infected with Lassa virus or are exposed to infected humans. Hospital staff are not at great risk for infection as long as protective measures are taken.

Risk Factors in the Development of Lassa Fever

The following are considered risk factors for developing Lassa fever:

  • Travel to endemic region (West Africa)
  • Exposure to infected individuals
  • Exposure to rodents (Mastomys natalensis rat/mouse) or contaminated household items (including food)
  • Occupational exposure in healthcare settings

Risk Factors in the Development of Lassa Fever-Associated Complications and Death

Level of Risk Upon Exposure

  • Individuals at greatest risk of Lassa virus infection are those who live in or visit endemic regions, including Sierra Leone, Liberia, Guinea, and Nigeria and have exposure to the multimammate rat. Risk of exposure may also exist in other west African countries where Mastomys rodents exist. Hospital staff are not at great risk for infection as long as protective measures and proper sterilization methods are used. [1]
Level of risk related to exposure to a patient with Lassa fever
High Risk
▸ Exposure from a percutaneous injury (i.e. needlestick or cut with a sharp object) to blood, tissue or other body fluids that are potentially infectious (e.g: urine, vomitus or stool).
▸ Exposure from direct unprotected contact with potentially infectious material (e.g: touching vomitus with an ungloved hand).
Mucosal exposure (eg. of eyes, nose or mouth) to splashes or droplet of potentially infectious blood and body fluid or sexual contact with a symptomatic partner.
Low Risk
▸ Sharing a room or sitting in a vehicle within 6 feet (i.e. coughing distance) of a potentially infectious person without direct contact with a potentially infectious material.
▸ Providing routine medical care while using personal protective equipment (PPE) appropriately.
▸ Routine cleaning and laundry of contaminated linens and surfaces while using personal protective equipment (PPE) appropriately.
▸ Transport of a potentially infectious patient or specimen without direct contact with potentially infectious material.
▸ Handling of clinical specimen while using personal protective equipment (PPE) appropriately.

References

  1. "The Centers for Disease Control and Prevention".


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