Mediastinitis natural history, complications and prognosis: Difference between revisions
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{{Mediastinitis}} | {{Mediastinitis}} | ||
{{CMG}} | {{CMG}} {{AE}} {{AG}} | ||
==Overview== | ==Overview== | ||
If left untreated, fibrosing mediastinitis may progress to [[sepsis]] and subsequently, death.<ref name=AAA> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref> Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.<ref name="pmid23351519">{{cite journal| author=Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A| title=[Mediastinitis]. | journal=Arch Bronconeumol | year= 2011 | volume= 47 Suppl 8 | issue= | pages= 32-6 | pmid=23351519 | doi=10.1016/S0300-2896(11)70065-5 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23351519 }} </ref> Common complications of mediastinitis include [[sepsis]] and [[pneumonia]]. | |||
==Natural History== | ==Natural History== | ||
If left untreated, fibrosing mediastinitis may progress | If left untreated, fibrosing mediastinitis may progress to [[sepsis]] and subsequently, death.<ref name=AAA> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref> Mortality rates related to mediastinitis vary, with some estimates predicting rates greater than 60%.<ref name="pmid23351519">{{cite journal| author=Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A| title=[Mediastinitis]. | journal=Arch Bronconeumol | year= 2011 | volume= 47 Suppl 8 | issue= | pages= 32-6 | pmid=23351519 | doi=10.1016/S0300-2896(11)70065-5 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23351519 }} </ref> | ||
==Complications== | ==Complications== | ||
[[ | Common complications of mediastinitis include the following:<ref name=AAA> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref><ref> Fibrosing Mediastinitis. National Organization for Rare Disorders (2015). https://rarediseases.org/rare-diseases/fibrosing-mediastinitis/ Accessed on September 25, 2015</ref> | ||
*[[Sepsis]] | |||
*Spread of the [[infection]] to the: | *Spread of the [[infection]] to the: | ||
**[[Bones]] | **[[Bones]] | ||
**[[Heart]] | **[[Heart]] | ||
**[[Lungs]] | **[[Lungs]] | ||
*[[Scarring]] | |||
*[[Pneumonia]] | |||
==Prognosis== | ==Prognosis== | ||
[[Mediastinitis] | Generally, patients with mediastinitis have a poor prognosis with a mortality rate near 40%.<ref name="pmid12975075">{{cite journal |vauthors=Macrí P, Jiménez MF, Novoa N, Varela G |title=[A descriptive analysis of a series of patients diagnosed with acute mediastinitis] |language=Spanish; Castilian |journal=Arch. Bronconeumol. |volume=39 |issue=9 |pages=428–30 |year=2003 |pmid=12975075 |doi= |url=}}</ref> Mediastinitis among post-sternotomy patients has a particularly poor prognosis with an elevated risk of mortality near 60%.<ref name="pmid23351519">{{cite journal| author=Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A| title=[Mediastinitis]. | journal=Arch Bronconeumol | year= 2011 | volume= 47 Suppl 8 | issue= | pages= 32-6 | pmid=23351519 | doi=10.1016/S0300-2896(11)70065-5 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23351519 }} </ref> Prognosis improves with [[antimicrobial]] therapy.<ref name=AAA> Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Pulmonology]] | |||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Latest revision as of 18:02, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]
Overview
If left untreated, fibrosing mediastinitis may progress to sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, though some estimates predict rates greater than 60%.[2] Common complications of mediastinitis include sepsis and pneumonia.
Natural History
If left untreated, fibrosing mediastinitis may progress to sepsis and subsequently, death.[1] Mortality rates related to mediastinitis vary, with some estimates predicting rates greater than 60%.[2]
Complications
Common complications of mediastinitis include the following:[1][3]
Prognosis
Generally, patients with mediastinitis have a poor prognosis with a mortality rate near 40%.[4] Mediastinitis among post-sternotomy patients has a particularly poor prognosis with an elevated risk of mortality near 60%.[2] Prognosis improves with antimicrobial therapy.[1]
References
- ↑ 1.0 1.1 1.2 1.3 Mediastinitis: a potentially lethal infection. Thoracics (2012). http://thoracics.org/2012/03/03/mediastinitis-noncardiac-surgery/ Accessed on September 25, 2015.
- ↑ 2.0 2.1 2.2 Martínez Vallina P, Espinosa Jiménez D, Hernández Pérez L, Triviño Ramírez A (2011). "[Mediastinitis]". Arch Bronconeumol. 47 Suppl 8: 32–6. doi:10.1016/S0300-2896(11)70065-5. PMID 23351519.
- ↑ Fibrosing Mediastinitis. National Organization for Rare Disorders (2015). https://rarediseases.org/rare-diseases/fibrosing-mediastinitis/ Accessed on September 25, 2015
- ↑ Macrí P, Jiménez MF, Novoa N, Varela G (2003). "[A descriptive analysis of a series of patients diagnosed with acute mediastinitis]". Arch. Bronconeumol. (in Spanish; Castilian). 39 (9): 428–30. PMID 12975075.