Naegleria infection: Difference between revisions

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[[Image:Naegleria fowleri.jpg|thumb|250px|Histopathology of amoebic meningoencephalitis]]
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{{DiseaseDisorder infobox
| Name          = Naegleria infection
| Image         = Naegleria fowleri.jpg
}}
{{Naegleria infection}}
'''For patient information, click [[Naegleria infection (patient information)|here]]'''
 
{{CMG}}
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==[[Naegleria infection overview|Overview]]==


==[[Naegleria infection historical perspective|Historical Perspective]]==


== Treatment ==
==[[Naegleria infection pathophysiology|Pathophysiology]]==
=== Pharmacotherapy ===


==== Acute Pharmacotherapies ====
==[[Naegleria infection causes|Causes]]==
Eye and skin infections caused by Acanthamoeba spp. are generally treatable.  The treatment of choice is topical use of polyhexamthylene biguanide (PHMB) or chlorhexidene gluconate with or without Brolene. Although most cases of brain (CNS) infection with Acanthamoeba have resulted in death, patients have recovered from the infection with proper treatment.  Amphotericin B has been successfully used in some cases to treat PAM caused by Naegleria fowleri.


=== Surgery and Device Based Therapy ===
==[[Naegleria infection differential diagnosis|Differentiating Naegleria Infection from other Diseases]]==
Keratoplasty is often necessary in severe infections.


==== Indications for Surgery ====
==[[Naegleria infection epidemiology and demographics|Epidemiology and Demographics]]==
Severe infections


=== Primary Prevention ===
==[[Naegleria infection risk factors|Risk Factors]]==
*Avoid swimming or jumping into bodies of warm fresh water, hot springs, and thermally-polluted water such a water around power plants.
*Avoid swimming or jumping into fresh water during periods of high temperature and low water volume.
*Hold the nose shut or use nose clips when jumping or diving into bodies of warm fresh water such as lakes, rivers, or hot springs.
*Avoid digging in or stirring up the sediment while swimming in shallow water areas.
*Do not swim in areas posted as "no swimming" or in areas warning about an increased risk of Naegleria infection.


==References==
==[[Naegleria infection natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
#http://www.dpd.cdc.gov/dpdx/HTML/FreeLivingAmebic.htm
#http://www.cdc.gov/ncidod/dpd/parasites/naegleria/factsht_naegleria.htm
#http://en.wikipedia.org/wiki/Naegleria_fowleri
 
== Acknowledgements ==
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.


==Diagnosis==
[[Naegleria infection history and symptoms|History and Symptoms]] | [[Naegleria infection physical examination|Physical Examination]] | [[Naegleria infection laboratory findings|Laboratory Findings]] | [[Naegleria infection other diagnostic studies|Other Diagnostic Studies]]
==Treatment==
[[Naegleria infection medical therapy|Medical Therapy]] | [[Naegleria infection surgery|Surgery]] | [[Naegleria infection primary prevention|Primary Prevention]] | [[Naegleria infection cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Naegleria infection future or investigational therapies|Future or Investigational Therapies]]
==Case Studies==
[[Naegleria infection case study one|Case #1]]
==Related Chapters==
*[[Acanthamoeba]]


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[[Category:Disease]]
[[Category:Disease]]
[[Category:Infectious disease]]
 
[[Category:Neurology]]
 
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Latest revision as of 18:10, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Naegleria Infection from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

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Case #1

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