Naegleria infection (patient information): Difference between revisions

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==What are the symptoms of Naegleria infection?==
==What are the symptoms of Naegleria infection?==
Naegleria fowleri causes the disease primary amebic meningoencephalitis (PAM), a brain infection that leads to the destruction of brain tissue. In its early stages, symptoms of PAM may be similar to symptoms of bacterial meningitis.
Naegleria fowleri causes the disease primary amebic meningoencephalitis (PAM), a brain infection that leads to the destruction of brain tissue. In its early stages, symptoms of PAM may be similar to symptoms of [[bacterial meningitis]].
 
Initial symptoms of PAM start about 5 days (range 1 to 7 days) after infection. The initial symptoms may include [[headache]], [[fever]], [[nausea]], or [[vomiting]]. Later symptoms can include [[stiff neck]], [[confusion]], lack of attention to people and surroundings, [[loss of balance]], [[seizures]], and [[hallucinations]]. After the start of symptoms, the disease progresses rapidly and usually causes [[death]] within about 5 days (range 1 to 12 days).


Initial symptoms of PAM start about 5 days (range 1 to 7 days) after infection. The initial symptoms may include headache, fever, nausea, or vomiting. Later symptoms can include stiff neck, confusion, lack of attention to people and surroundings, loss of balance, seizures, and hallucinations. After the start of symptoms, the disease progresses rapidly and usually causes death within about 5 days (range 1 to 12 days).
==What causes Naegleria infection?==
==What causes Naegleria infection?==
Only one species (type) of Naegleria infects people: [[Naegleria fowleri]].'''
Only one species (type) of Naegleria infects people: [[Naegleria fowleri]].'''
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==Who is at highest risk?==
==Who is at highest risk?==
Naegleria fowleri is found around the world. In the United States, the majority of infections have been caused by Naegleria fowleri from warm freshwater located in southern-tier states. The ameba can be found in:
Naegleria fowleri is found around the world. In the United States, the majority of infections have been caused by Naegleria fowleri from warm freshwater located in southern-tier states. The ameba can be found in:
* Factors that can increase your risk of viral meningitis include:
* Factors that can increase your risk of [[meningitis]] include:
* Bodies of warm freshwater, such as lakes and rivers
* Bodies of warm [[freshwater]], such as lakes and rivers
* Geothermal (naturally hot) water, such as hot springs
* Geothermal (naturally hot) water, such as hot springs
* Warm water discharge from industrial plants
* Warm water discharge from industrial plants
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Naegleria fowleri is not found in salt water, like the ocean
Naegleria fowleri is not found in salt water, like the ocean
==When to seek urgent medical care?==
==When to seek urgent medical care?==
People should seek medical care immediately whenever they develop a sudden onset of fever, headache, stiff neck, and vomiting, particularly if they have been in warm freshwater recently.
People should seek medical care immediately whenever they develop a sudden onset of [[fever]], [[headache]], [[stiff neck]], and [[vomiting]], particularly if they have been in warm [[freshwater]] recently.
 
==Treatment options==
==Treatment options==
Several drugs are effective against Naegleria fowleri in the laboratory. However, their effectiveness is unclear since almost all infections have been fatal, even when people were treated.
Several drugs are effective against Naegleria fowleri in the laboratory. However, their effectiveness is unclear since almost all infections have been fatal, even when people were treated.
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==Prevention==
==Prevention==
Naegleria fowleri is found in many warm freshwater lakes and rivers in the United States, particularly in southern tier states. It is likely that a low risk of Naegleria fowleri infection will always exist with recreational use of warm freshwater lakes, rivers, and hot springs. The low number of infections makes it difficult to know why a few people have been infected compared to the millions of other people using the same or similar waters across the U.S. The only certain way to prevent a Naegleria fowleri infection is to refrain from water-related activities in or with warm, untreated, or poorly-treated water.
Naegleria fowleri is found in many warm freshwater lakes and rivers in the United States, particularly in southern tier states. It is likely that a low risk of Naegleria fowleri infection will always exist with recreational use of warm freshwater lakes, rivers, and hot springs. The low number of infections makes it difficult to know why a few people have been infected compared to the millions of other people using the same or similar waters across the U.S. The only certain way to prevent a Naegleria fowleri infection is to refrain from water-related activities in or with warm, untreated, or poorly-treated water.
 
If you do plan to take part in water-related activities, some measures that might reduce risk include:
* If you do plan to take part in water-related activities, some measures that might reduce risk include:
* Avoid water-related activities in warm freshwater during periods of high water temperature and low water levels.
* Avoid water-related activities in warm freshwater during periods of high water temperature and low water levels.
* Hold the nose shut or use nose clips when taking part in water-related activities in bodies of warm freshwater.
* Hold the [[nose]] shut or use nose clips when taking part in water-related activities in bodies of warm freshwater.
* Avoid digging in, or stirring up, the sediment while taking part in water-related activities in shallow, warm freshwater areas.
* Avoid digging in, or stirring up, the sediment while taking part in water-related activities in shallow, warm [[freshwater]] areas.
* If you are irrigating, flushing, or rinsing your sinuses (for example, by using a neti pot), use water that has been:
* If you are irrigating, flushing, or rinsing your sinuses (for example, by using a neti pot), use water that has been:
* Distilled;
** Distilled
* Sterilized;
** Sterilized
* Previously boiled for 1 minute (at elevations above 6,500 feet, boil for 3 minutes) and left to cool;
** Previously boiled for 1 minute (at elevations above 6,500 feet, boil for 3 minutes) and left to cool
* Filtered, using a filter with an absolute pore size of 1 micron or smaller.
** Filtered, using a filter with an absolute pore size of 1 micron or smaller.
* Rinse the irrigation device after each use with water that has been distilled, sterilized, filtered, or previously boiled and leave the device open to air dry completely.
* Rinse the irrigation device after each use with water that has been distilled, sterilized, filtered, or previously boiled and leave the device open to air dry completely.


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[[Category: Patient information]]
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[[Category:Disease]]
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[[Category:Neurology]]
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Latest revision as of 18:10, 18 September 2017

Naegleria infection

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

When to seek urgent medical care?

Treatment options

Where to find medical care for Naegleria infection?

Prevention

Naegleria infection On the Web

Ongoing Trials at Clinical Trials.gov

Images of Naegleria infection

Videos on Naegleria infection

FDA on Naegleria infection

CDC on Naegleria infection

Naegleria infection in the news

Blogs on Naegleria infection

Directions to Hospitals Treating Naegleria infection

Risk calculators and risk factors for Naegleria infection

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

Overview

Naegleria is an amoeba (single-celled living organism) commonly found in warm freshwater (for example, lakes, rivers, and hot springs) and soil.

What are the symptoms of Naegleria infection?

Naegleria fowleri causes the disease primary amebic meningoencephalitis (PAM), a brain infection that leads to the destruction of brain tissue. In its early stages, symptoms of PAM may be similar to symptoms of bacterial meningitis.

Initial symptoms of PAM start about 5 days (range 1 to 7 days) after infection. The initial symptoms may include headache, fever, nausea, or vomiting. Later symptoms can include stiff neck, confusion, lack of attention to people and surroundings, loss of balance, seizures, and hallucinations. After the start of symptoms, the disease progresses rapidly and usually causes death within about 5 days (range 1 to 12 days).

What causes Naegleria infection?

Only one species (type) of Naegleria infects people: Naegleria fowleri.

Who is at highest risk?

Naegleria fowleri is found around the world. In the United States, the majority of infections have been caused by Naegleria fowleri from warm freshwater located in southern-tier states. The ameba can be found in:

  • Factors that can increase your risk of meningitis include:
  • Bodies of warm freshwater, such as lakes and rivers
  • Geothermal (naturally hot) water, such as hot springs
  • Warm water discharge from industrial plants
  • Geothermal (naturally hot) drinking water sources
  • Soil
  • Swimming pools that are poorly maintained, minimally-chlorinated, and/or un-chlorinated
  • Water heaters with temperatures less than 47°C

Naegleria fowleri is not found in salt water, like the ocean

When to seek urgent medical care?

People should seek medical care immediately whenever they develop a sudden onset of fever, headache, stiff neck, and vomiting, particularly if they have been in warm freshwater recently.

Treatment options

Several drugs are effective against Naegleria fowleri in the laboratory. However, their effectiveness is unclear since almost all infections have been fatal, even when people were treated.

Where to find medical care for Naegleria infection?

Directions to Hospitals Treating Naegleria infection

Prevention

Naegleria fowleri is found in many warm freshwater lakes and rivers in the United States, particularly in southern tier states. It is likely that a low risk of Naegleria fowleri infection will always exist with recreational use of warm freshwater lakes, rivers, and hot springs. The low number of infections makes it difficult to know why a few people have been infected compared to the millions of other people using the same or similar waters across the U.S. The only certain way to prevent a Naegleria fowleri infection is to refrain from water-related activities in or with warm, untreated, or poorly-treated water. If you do plan to take part in water-related activities, some measures that might reduce risk include:

  • Avoid water-related activities in warm freshwater during periods of high water temperature and low water levels.
  • Hold the nose shut or use nose clips when taking part in water-related activities in bodies of warm freshwater.
  • Avoid digging in, or stirring up, the sediment while taking part in water-related activities in shallow, warm freshwater areas.
  • If you are irrigating, flushing, or rinsing your sinuses (for example, by using a neti pot), use water that has been:
    • Distilled
    • Sterilized
    • Previously boiled for 1 minute (at elevations above 6,500 feet, boil for 3 minutes) and left to cool
    • Filtered, using a filter with an absolute pore size of 1 micron or smaller.
  • Rinse the irrigation device after each use with water that has been distilled, sterilized, filtered, or previously boiled and leave the device open to air dry completely.

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