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{{Southern tick-associated rash illness}}
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==Overview==
 
==Pathophysiology==
==Pathophysiology==
'''Ticks Transmit Lyme Disease'''
The Lyme disease bacterium, Borrelia burgdorferi, normally lives in mice, squirrels and other small animals. It is transmitted among these animals – and to humans -- through the bites of certain species of ticks.   
In the northeastern and north-central United States, the blacklegged tick (or deer tick, Ixodes scapularis) transmits Lyme disease. In the Pacific coastal United States, the disease is spread by the western blacklegged tick (Ixodes pacificus). Other tick species found in the United States have not been shown to transmit Borrelia burgdorferi. Blacklegged ticks live for two years and have three feeding stages: larvae, nymph, and adult. When a young tick feeds on an infected animal, the tick takes the bacterium into its body along with the blood meal.
The bacterium then lives in the gut of the tick. If the tick feeds again, it can transmit the bacterium to its new host. Usually the new host is another small rodent, but sometimes the new host is a human.
Most cases of human illness occur in the late spring and summer when the tiny nymphs are most active and human outdoor activity is greatest.
Although adult ticks often feed on deer, these animals do not become infected. Deer are nevertheless important in transporting ticks and maintaining tick populations. 
'''Other Modes of Transmission'''
''Person-to-Person''
There is no evidence that Lyme disease is transmitted from person-to-person. For example, a person cannot get infected from touching, kissing or having sex with a person who has Lyme disease.
''During Pregnancy & While Breastfeeding''


Lyme disease acquired during pregnancy may lead to infection of the placenta and possible stillbirth, however, no negative effects on the fetus have been found when the mother receives appropriate antibiotic treatment. There are no reports of Lyme disease transmission from breast milk.
Most ticks go through four life stages: egg, six-legged larva, eight-legged nymph, and adult. After hatching from the eggs, ticks must eat blood at every stage to survive. Ticks that require this many hosts can take up to 3 years to complete their full life cycle, and most will die because they don't find a host for their next feeding.
[[Image:Tick_sizes.jpg|center|400px]]
Ticks can feed on mammals, birds, reptiles, and amphibians. Most ticks prefer to have a different host animal at each stage of their life, as shown below:
[[Image:Lifecycle.jpg|center|500px]]


''From Blood''


Although no cases of Lyme disease have been linked to blood transfusion, scientists have found that the Lyme disease bacteria can live in blood that is stored for donation. Individuals being treated for Lyme disease with an antibiotic should not donate blood. Individuals who have completed antibiotic treatment for Lyme disease may be considered as potential blood donors.  
Ticks find their hosts by detecting animals´ breath and body odors, or by sensing body heat, moisture, and vibrations. Some species can even recognize a shadow. In addition, ticks pick a place to wait by identifying well-used paths. Then they wait for a host, resting on the tips of grasses and shrubs. Ticks can't fly or jump, but many tick species wait in a position known as "questing".


''From Pets''
While questing, ticks hold onto leaves and grass by their third and fourth pair of legs. They hold the first pair of legs outstretched, waiting to climb on to the host. When a host brushes the spot where a tick is waiting, it quickly climbs aboard. Some ticks will attach quickly and others will wander, looking for places like the ear, or other areas where the skin is thinner.


Although dogs and cats can get Lyme disease, there is no evidence that they spread the disease directly to their owners. However, pets can bring infected ticks into your home or yard. Consider protecting your pet, and possibly yourself, through the use of tick control products for animals.
The lone star tick, Amblyomma americanum, is found throughout the eastern, southeastern and south-central states. The distribution, range and abundance of the lone star tick have increased over the past 20-30 years, and lone star ticks have been recorded in large numbers as far north as Maine and as far west as central Texas and Oklahoma. All three life stages (larva, nymph, adult) of the lone star tick will feed on humans, and may be quite aggressive. Lone star ticks will also feed readily on other animals, including dogs and cats, and may be brought into the home on pets. The saliva from lone star ticks can be irritating; redness and discomfort at a bite site does not necessarily indicate an infection.


''Other Transmission''
=== Transmission ===
Ticks transmit pathogens that cause disease through the process of feeding.


You will not get Lyme disease from eating venison or squirrel meat, but in keeping with general food safety principles meat should always be cooked thoroughly. Note that hunting and dressing deer or squirrels may bring you into close contact with infected ticks.  
* Depending on the tick species and its stage of life, preparing to feed can take from 10 minutes to 2 hours. When the tick finds a feeding spot, it grasps the skin and cuts into the surface.
 
* The tick then inserts its feeding tube. Many species also secrete a cement-like substance that keeps them firmly attached during the meal. The feeding tube can have barbs which help keep the tick in place.
There is no credible evidence that Lyme disease can be transmitted through air, food, water, or from the bites of mosquitoes, flies, fleas, or lice.
* Ticks also can secrete small amounts of saliva with anesthetic properties so that the animal or person can't feel that the tick has attached itself. If the tick is in a sheltered spot, it can go unnoticed.
* A tick will suck the blood slowly for several days. If the host animal has a bloodborne infection, the tick will ingest the pathogens with the blood.
* Small amounts of saliva from the tick may also enter the skin of the host animal during the feeding process. If the tick contains a pathogen, the organism may be transmitted to the host animal in this way.
* After feeding, most ticks will drop off and prepare for the next life stage. At its next feeding, it can then transmit an acquired disease to the new host.


==References==
==References==
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Latest revision as of 19:05, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: : Vishnu Vardhan Serla M.B.B.S. [2]

Pathophysiology

Most ticks go through four life stages: egg, six-legged larva, eight-legged nymph, and adult. After hatching from the eggs, ticks must eat blood at every stage to survive. Ticks that require this many hosts can take up to 3 years to complete their full life cycle, and most will die because they don't find a host for their next feeding.

Ticks can feed on mammals, birds, reptiles, and amphibians. Most ticks prefer to have a different host animal at each stage of their life, as shown below:


Ticks find their hosts by detecting animals´ breath and body odors, or by sensing body heat, moisture, and vibrations. Some species can even recognize a shadow. In addition, ticks pick a place to wait by identifying well-used paths. Then they wait for a host, resting on the tips of grasses and shrubs. Ticks can't fly or jump, but many tick species wait in a position known as "questing".

While questing, ticks hold onto leaves and grass by their third and fourth pair of legs. They hold the first pair of legs outstretched, waiting to climb on to the host. When a host brushes the spot where a tick is waiting, it quickly climbs aboard. Some ticks will attach quickly and others will wander, looking for places like the ear, or other areas where the skin is thinner.

The lone star tick, Amblyomma americanum, is found throughout the eastern, southeastern and south-central states. The distribution, range and abundance of the lone star tick have increased over the past 20-30 years, and lone star ticks have been recorded in large numbers as far north as Maine and as far west as central Texas and Oklahoma. All three life stages (larva, nymph, adult) of the lone star tick will feed on humans, and may be quite aggressive. Lone star ticks will also feed readily on other animals, including dogs and cats, and may be brought into the home on pets. The saliva from lone star ticks can be irritating; redness and discomfort at a bite site does not necessarily indicate an infection.

Transmission

Ticks transmit pathogens that cause disease through the process of feeding.

  • Depending on the tick species and its stage of life, preparing to feed can take from 10 minutes to 2 hours. When the tick finds a feeding spot, it grasps the skin and cuts into the surface.
  • The tick then inserts its feeding tube. Many species also secrete a cement-like substance that keeps them firmly attached during the meal. The feeding tube can have barbs which help keep the tick in place.
  • Ticks also can secrete small amounts of saliva with anesthetic properties so that the animal or person can't feel that the tick has attached itself. If the tick is in a sheltered spot, it can go unnoticed.
  • A tick will suck the blood slowly for several days. If the host animal has a bloodborne infection, the tick will ingest the pathogens with the blood.
  • Small amounts of saliva from the tick may also enter the skin of the host animal during the feeding process. If the tick contains a pathogen, the organism may be transmitted to the host animal in this way.
  • After feeding, most ticks will drop off and prepare for the next life stage. At its next feeding, it can then transmit an acquired disease to the new host.

References

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