Trichinosis medical therapy: Difference between revisions
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(Created page with "{{Trichinosis}} {{CMG}} ==Overview== '''Trichinosis''', also called '''trichinellosis''', or '''trichiniasis''', is a parasitic disease caused by eating raw or undercook...") |
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{{Trichinosis}} | {{Trichinosis}} | ||
{{CMG}} | {{CMG}} {{AE}} {{DL}} | ||
==Overview== | |||
The mainstay of [[therapy]] for trichinosis are [[Anthelmintic|anthelmintics drugs]] such as [[albendazole]] or [[mebendazole]].<ref name="d">Trichinellosis. CDC. http://www.cdc.gov/parasites/trichinellosis/health_professionals/index.html#tx. Accessed on January 26, 2016</ref> | |||
==Medical Therapy== | |||
=== Treatment for asymptomatic, abortive and mild patients: === | |||
*Administration of [[Anthelmintic|anthelmintics]] | |||
*Administration of [[glucocorticoids]] if needed. | |||
== | === Treatment for pronounced and severe patients: === | ||
*Hospitalization | |||
**Compulsory for severe cases | |||
*Administration of [[glucocorticoids]], [[Anthelmintic|anthelmintics]] and [[analgesics]]. | |||
*Administration of fluids and electrolytes <ref name="pmid19136437">{{cite journal| author=Gottstein B, Pozio E, Nöckler K| title=Epidemiology, diagnosis, treatment, and control of trichinellosis. | journal=Clin Microbiol Rev | year= 2009 | volume= 22 | issue= 1 | pages= 127-45, Table of Contents | pmid=19136437 | doi=10.1128/CMR.00026-08 | pmc=PMC2620635 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19136437 }} </ref> | |||
== Antihelmintic Regimen<ref name="d">Trichinellosis. CDC. http://www.cdc.gov/parasites/trichinellosis/health_professionals/index.html#tx. Accessed on January 26, 2016</ref> == | |||
::'''Trichinosis in adult and children ≥2yrs of age''' | |||
:::* Preferred regimen (1): [[Albendazole]] 400 mg PO bid for 8 to 14 days {{or}} [[Mebendazole]] 200-400 mg PO tid for 3 days, then 400-500 mg PO tid for 10 days | |||
:::* Note: | |||
:::**[[Albendazole]]: | |||
:::***''Pregnancy'': Albendazole is [[Pregnancy category (pharmaceutical)|pregnancy category C]]. | |||
:::***''Lactation:'' It is not known whether albendazole is excreted in human milk. | |||
:::***''Pedriatic patients'': The safety of albendazole in children less than 6 years old is not certain. Studies of the use of albendazole in children as young as one year old suggest that its use is safe. | |||
:::**[[Mebendazole]]: | |||
:::***Pregnancy: Mebendazole is in pregnancy category C. | |||
:::***Lactation: It is not known whether mebendazole is excreted in breast milk. The WHO classifies mebendazole as compatible with breastfeeding and allows the use of mebendazole in lactating women. | |||
:::***Pedriatic patients: The safety of mebendazole in children has not been established. | |||
==References== | ==References== | ||
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Latest revision as of 19:01, 18 September 2017
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Trichinosis Microchapters |
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Trichinosis medical therapy On the Web |
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Risk calculators and risk factors for Trichinosis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Danitza Lukac
Overview
The mainstay of therapy for trichinosis are anthelmintics drugs such as albendazole or mebendazole.[1]
Medical Therapy
Treatment for asymptomatic, abortive and mild patients:
- Administration of anthelmintics
- Administration of glucocorticoids if needed.
Treatment for pronounced and severe patients:
- Hospitalization
- Compulsory for severe cases
- Administration of glucocorticoids, anthelmintics and analgesics.
- Administration of fluids and electrolytes [2]
Antihelmintic Regimen[1]
- Trichinosis in adult and children ≥2yrs of age
- Preferred regimen (1): Albendazole 400 mg PO bid for 8 to 14 days OR Mebendazole 200-400 mg PO tid for 3 days, then 400-500 mg PO tid for 10 days
- Note:
- Albendazole:
- Pregnancy: Albendazole is pregnancy category C.
- Lactation: It is not known whether albendazole is excreted in human milk.
- Pedriatic patients: The safety of albendazole in children less than 6 years old is not certain. Studies of the use of albendazole in children as young as one year old suggest that its use is safe.
- Mebendazole:
- Pregnancy: Mebendazole is in pregnancy category C.
- Lactation: It is not known whether mebendazole is excreted in breast milk. The WHO classifies mebendazole as compatible with breastfeeding and allows the use of mebendazole in lactating women.
- Pedriatic patients: The safety of mebendazole in children has not been established.
- Albendazole:
- Trichinosis in adult and children ≥2yrs of age
References
- ↑ 1.0 1.1 Trichinellosis. CDC. http://www.cdc.gov/parasites/trichinellosis/health_professionals/index.html#tx. Accessed on January 26, 2016
- ↑ Gottstein B, Pozio E, Nöckler K (2009). "Epidemiology, diagnosis, treatment, and control of trichinellosis". Clin Microbiol Rev. 22 (1): 127–45, Table of Contents. doi:10.1128/CMR.00026-08. PMC 2620635. PMID 19136437.