Addison's disease history and symptoms: Difference between revisions
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{{CMG}} ; {{AE}} {{ADG}} | {{CMG}} ; {{AE}} {{ADG}} | ||
==Overview== | ==Overview== | ||
Addison's disease often has an insidious onset. In many cases, the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful [[illness]] or situation. Acute adrenal insufficiency should be considered in patients presenting with [[abdominal pain]], [[nausea]], [[diarrhea]], [[hypotension]], and [[fever]]. A detailed and thorough history is necessary. Specific areas of focus when obtaining a history from the patient of Addison's disease include recent changes in diet, any signs of [[postural hypotension]] and history of [[cancer]] or other autoimmune diseases, [[tuberculosis]] or any exposure to anyone who has been diagnosed with [[tuberculosis]]. | |||
==History and | ==History== | ||
=== | A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of Addison's disease include:<ref name="pmid22907517">{{cite journal |vauthors=Quinkler M |title=[Addison's disease] |language=German |journal=Med Klin Intensivmed Notfmed |volume=107 |issue=6 |pages=454–9 |year=2012 |pmid=22907517 |doi=10.1007/s00063-012-0112-3 |url=}}</ref> | ||
*Recent changes in diet | |||
**Patients with Addison disease often crave salty foods and are often [[Anorexia|anorexic]] | |||
*Irregular [[menstruation]] | |||
**[[Oligomenorrhea]] or [[amenorrhea]] are features of Addison disease | |||
*Any signs of [[postural hypotension]] | |||
*Any recent changes in [[weight]] | |||
*History of [[tuberculosis]] or any exposure to someone with [[tuberculosis]] | |||
*History of [[malignancy]] | |||
*History of other [[autoimmune disease]], such as [[Graves' disease|Graves disease]], [[Hashimoto's thyroiditis]], [[hypoparathyroidism]], [[vitiligo]], [[pernicious anemia]] or [[diabetes mellitus]] | |||
*[[Family history]] of Addison's disease or any other [[Adrenal gland|adrenal]] disorder | |||
==Symptoms== | |||
Addison's disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness. Acute adrenal insufficiency should be considered in patients presenting with [[abdominal pain]], [[nausea]], [[diarrhea]], [[hypotension]] and [[fever]].<ref name="pmid23633816">{{cite journal |vauthors=Sarkar SB, Sarkar S, Ghosh S, Bandyopadhyay S |title=Addison's disease |journal=Contemp Clin Dent |volume=3 |issue=4 |pages=484–6 |year=2012 |pmid=23633816 |pmc=3636818 |doi=10.4103/0976-237X.107450 |url=}}</ref><ref name="pmid12788587">{{cite journal |vauthors=Arlt W, Allolio B |title=Adrenal insufficiency |journal=Lancet |volume=361 |issue=9372 |pages=1881–93 |year=2003 |pmid=12788587 |doi=10.1016/S0140-6736(03)13492-7 |url=}}</ref> | |||
===Common Symptoms=== | |||
*[[Weakness]] | |||
*[[Fatigue|Chronic fatigue]] | |||
*[[Weight loss]] | |||
*[[Anorexia]] | |||
*[[Nausea]] | |||
*[[Vomiting]] | |||
*[[Diarrhea]] | |||
*Intolerance of temperature extremes | |||
*[[Abdominal pain]] | |||
*[[Amenorrhea]] | |||
*Craving for salty foods | |||
| | *[[Depression]] | ||
*[[Dizziness]] | |||
===Symptoms of Addisonian crisis=== | |||
Symptoms of Addisonian crisis include: | |||
*[[Dizziness]], [[generalized weakness]] ([[fatigue]]) | |||
| | *[[Anorexia]] | ||
| | *Sharp, sudden [[pain]] in the [[abdomen]], [[legs]], or [[lower back]] | ||
| | *Severe [[vomiting]] and [[diarrhea]] | ||
* | *[[Dehydration]] | ||
* | *Loss of [[consciousness]] | ||
* Nausea | *[[Hypoglycemia]] | ||
* [[ | |||
* [[ | |||
* | |||
* | |||
==References== | ==References== | ||
Latest revision as of 20:13, 11 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Addison's disease often has an insidious onset. In many cases, the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness or situation. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension, and fever. A detailed and thorough history is necessary. Specific areas of focus when obtaining a history from the patient of Addison's disease include recent changes in diet, any signs of postural hypotension and history of cancer or other autoimmune diseases, tuberculosis or any exposure to anyone who has been diagnosed with tuberculosis.
History
A detailed and thorough history from the patient is necessary. Specific areas of focus when obtaining a history from the patient of Addison's disease include:[1]
- Recent changes in diet
- Patients with Addison disease often crave salty foods and are often anorexic
- Irregular menstruation
- Oligomenorrhea or amenorrhea are features of Addison disease
- Any signs of postural hypotension
- Any recent changes in weight
- History of tuberculosis or any exposure to someone with tuberculosis
- History of malignancy
- History of other autoimmune disease, such as Graves disease, Hashimoto's thyroiditis, hypoparathyroidism, vitiligo, pernicious anemia or diabetes mellitus
- Family history of Addison's disease or any other adrenal disorder
Symptoms
Addison's disease often has an insidious onset. In many cases the disease is only recognized when the patient presents with an acute crisis precipitated by a stressful illness. Acute adrenal insufficiency should be considered in patients presenting with abdominal pain, nausea, diarrhea, hypotension and fever.[2][3]
Common Symptoms
- Weakness
- Chronic fatigue
- Weight loss
- Anorexia
- Nausea
- Vomiting
- Diarrhea
- Intolerance of temperature extremes
- Abdominal pain
- Amenorrhea
- Craving for salty foods
- Depression
- Dizziness
Symptoms of Addisonian crisis
Symptoms of Addisonian crisis include:
- Dizziness, generalized weakness (fatigue)
- Anorexia
- Sharp, sudden pain in the abdomen, legs, or lower back
- Severe vomiting and diarrhea
- Dehydration
- Loss of consciousness
- Hypoglycemia
References
- ↑ Quinkler M (2012). "[Addison's disease]". Med Klin Intensivmed Notfmed (in German). 107 (6): 454–9. doi:10.1007/s00063-012-0112-3. PMID 22907517.
- ↑ Sarkar SB, Sarkar S, Ghosh S, Bandyopadhyay S (2012). "Addison's disease". Contemp Clin Dent. 3 (4): 484–6. doi:10.4103/0976-237X.107450. PMC 3636818. PMID 23633816.
- ↑ Arlt W, Allolio B (2003). "Adrenal insufficiency". Lancet. 361 (9372): 1881–93. doi:10.1016/S0140-6736(03)13492-7. PMID 12788587.