Toxic Adenoma (patient information): Difference between revisions
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==Overview== | ==Overview== | ||
A toxic adenoma is a benign [[tumor]] of the thyroid gland which produces excessive amounts of thyroid hormone. | A toxic adenoma is a benign [[tumor]] of the thyroid gland which produces excessive amounts of [[thyroid]] hormone. | ||
==What are the Symptoms of Toxic Adenoma?== | ==What are the Symptoms of Toxic Adenoma?== | ||
Patients with toxic adenomas typically present with signs and symptoms of thyrotoxicosis which include: | Patients with toxic adenomas typically present with signs and symptoms of [[thyrotoxicosis]] which include: | ||
*[[Fatigue]] | *[[Fatigue]] | ||
*Unintentional [[weight loss]] | *Unintentional [[weight loss]] | ||
| Line 22: | Line 22: | ||
*[[Irritability]] | *[[Irritability]] | ||
*Difficulty with mental concentration | *Difficulty with mental concentration | ||
* | *Hairloss | ||
==What Causes Toxic Adenoma?== | ==What Causes Toxic Adenoma?== | ||
| Line 28: | Line 28: | ||
==Who is at Highest Risk?== | ==Who is at Highest Risk?== | ||
Common [[risk factors]] in the development of toxic adenoma include: | |||
*[[Iodine deficiency]] | |||
*Young adult age | |||
*[[Family history]] of [[Thyroid nodule|thyroid nodules]] | |||
*Female gender | |||
==Diagnosis== | ==Diagnosis== | ||
Measurement of serum [[TSH]] is considered as the best initial test in the evaluation of [[thyroid]] disorders. The serum free [[T4]] and free or total [[T3]] levels are elevated or in the upper part of the normal range. | |||
==When to Seek Urgent Medical Care?== | ==When to Seek Urgent Medical Care?== | ||
Call your healthcare provider if you have symptoms of this condition. | |||
==Treatment Options== | ==Treatment Options== | ||
The mainstay of treatment for most patients with toxic adenoma includes [[radioiodine]], anti thyroid drugs. In patients with overt [[thyrotoxicosis]], [[Beta blockers|beta blocker]] will alleviate the signs and symptoms mediated by the increased [[beta-adrenergic]] activity. Alternative treatment modalities include [[percutaneous]] [[ethanol]] injection, thermoablation, or radiofrequency ablation. Antithyroid drugs are not routinely employed in the management of toxic adenoma. | |||
==Where to find Medical Care for Toxic Adenoma?== | ==Where to find Medical Care for Toxic Adenoma?== | ||
Medical care for toxic Adenoma can be found [https://www.google.com/maps/search/hospitals/ here]. | Medical care for toxic Adenoma can be found [https://www.google.com/maps/search/hospitals/ here]. | ||
==Prevention== | ==Prevention== | ||
There are no established measures for the primary prevention of toxic adenoma. | |||
==What to | ==What to expect (Outlook/Prognosis)?== | ||
[[Prognosis]] of toxic adenoma is generally good with treatment. About 45% to 75% of patients stay [[euthyroid]] following I-131 therapy. | |||
==Possible Complications== | ==Possible Complications== | ||
Common complications of toxic adenoma include | |||
*[[Atrial fibrillation]] | |||
*Neck compression | |||
*Bone mineral loss | |||
*[[Thyroid storm]] | |||
*I-131-related [[hypothyroidism]] | |||
==Sources== | ==Sources== | ||
Latest revision as of 15:18, 16 October 2017
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Toxic adenoma |
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Toxic adenoma On the Web |
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For the WikiDoc page for this topic, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
A toxic adenoma is a benign tumor of the thyroid gland which produces excessive amounts of thyroid hormone.
What are the Symptoms of Toxic Adenoma?
Patients with toxic adenomas typically present with signs and symptoms of thyrotoxicosis which include:
- Fatigue
- Unintentional weight loss
- Heat intolerance
- Diaphoresis
- Tremor
- Palpitations
- Diarrhea
- Anxiety
- Nervousness
- Irritability
- Difficulty with mental concentration
- Hairloss
What Causes Toxic Adenoma?
The most common cause of toxic adenoma is iodine deficiency.
Who is at Highest Risk?
Common risk factors in the development of toxic adenoma include:
- Iodine deficiency
- Young adult age
- Family history of thyroid nodules
- Female gender
Diagnosis
Measurement of serum TSH is considered as the best initial test in the evaluation of thyroid disorders. The serum free T4 and free or total T3 levels are elevated or in the upper part of the normal range.
When to Seek Urgent Medical Care?
Call your healthcare provider if you have symptoms of this condition.
Treatment Options
The mainstay of treatment for most patients with toxic adenoma includes radioiodine, anti thyroid drugs. In patients with overt thyrotoxicosis, beta blocker will alleviate the signs and symptoms mediated by the increased beta-adrenergic activity. Alternative treatment modalities include percutaneous ethanol injection, thermoablation, or radiofrequency ablation. Antithyroid drugs are not routinely employed in the management of toxic adenoma.
Where to find Medical Care for Toxic Adenoma?
Medical care for toxic Adenoma can be found here.
Prevention
There are no established measures for the primary prevention of toxic adenoma.
What to expect (Outlook/Prognosis)?
Prognosis of toxic adenoma is generally good with treatment. About 45% to 75% of patients stay euthyroid following I-131 therapy.
Possible Complications
Common complications of toxic adenoma include
- Atrial fibrillation
- Neck compression
- Bone mineral loss
- Thyroid storm
- I-131-related hypothyroidism
Sources
http://www.nlm.nih.gov/medlineplus/ency/article/000434.htm