Acromegaly screening: Difference between revisions

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==Overview==
==Overview==
According to the endocrine society, screening for acromegaly is recommended among patients with clinical features of acromegaly. These features include enlarged [[hands]] and [[feet]], [[frontal]] protrusion, and [[skin]] thickening. The screening is performed by measurement of the [[IGF-1]].
There is insufficient evidence to recommend routine screening for acromegaly.  


== Screening ==
== Screening ==
*According to the endocrine society, screening for acromegaly by measurement of IGF-1 is recommended among patients with the clinical features of acromegaly. These features include the following:<ref name="pmid25356808">{{cite journal| author=Katznelson L, Laws ER, Melmed S, Molitch ME, Murad MH, Utz A et al.| title=Acromegaly: an endocrine society clinical practice guideline. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 11 | pages= 3933-51 | pmid=25356808 | doi=10.1210/jc.2014-2700 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25356808  }} </ref>
There is insufficient evidence to recommend routine screening for acromegaly.  
**Enlarged [[hands]] and [[feet]]
**Change in the [[facial]] features
**[[Headache]]
**Increase [[sweating]]
**[[Paraesthesia]]
**[[Skin]] thickening
**Protrusion of the lower [[jaw]]
*Screening also is recommended in patients with associated conditions of acromegaly. Acromegaly is associated with different comorbidities so that screening is important in patients with these comorbidities which include:
**[[Diabetes mellitus|Diabetes Mellitus]]
**[[Carpal tunnel syndrome]]
**[[Arthritis]]
**[[Sleep apnea]]
**[[Hypertension]]


==References==
==References==

Latest revision as of 15:59, 26 October 2017