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==Overview==
==Overview==
Glucagonoma was first described in 1942 by Becker.
Glucagonoma was first described in 1942 by Becker. In 1966, McGavran was the first to report a case of [[hyperglucagonemia]] associated with cutaneous changes. In 1970, Wilkinson described the typical skin eruption in glucagonoma as [[necrolytic migratory erythema]].


==Historical Perspective==
==Historical Perspective==
*Fewer than 250 cases of glucagonoma have been described in the literature since their first description by Becker in 1942.<ref>Glucagonoma. Wikipedia. https://en.wikipedia.org/wiki/Glucagonoma. Accessed on October 13, 2015.</ref>
*In 1942, glucagonoma was first described by Becker.
*McGavran was first to report a case with hyperglucagonemia associated with cutaneous changes in 1962.<ref name="pmid22970401">{{cite journal| author=Afsharfard A, Atqiaee K, Lotfollahzadeh S, Alborzi M, Derakhshanfar A| title=Necrolytic migratory erythema as the first manifestation of glucagonoma. | journal=Case Rep Surg | year= 2012 | volume= 2012 | issue=  | pages= 974210 | pmid=22970401 | doi=10.1155/2012/974210 | pmc=PMC3434377 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22970401  }} </ref>
*Between 1942 and 1966, many authors tried to make associations between high level of [[glucagon]] and skin eruptions.
*In 1966, The first well-documented case of glucagonoma was reported by McGavran in a female with [[skin lesions]] and [[glucose intolerance]]. The author was the first to describe a correlation between [[skin lesions]] and [[Islet cell tumor|islet-cell tumors]].<ref name="pmid22970401">{{cite journal| author=Afsharfard A, Atqiaee K, Lotfollahzadeh S, Alborzi M, Derakhshanfar A| title=Necrolytic migratory erythema as the first manifestation of glucagonoma. | journal=Case Rep Surg | year= 2012 | volume= 2012 | issue=  | pages= 974210 | pmid=22970401 | doi=10.1155/2012/974210 | pmc=PMC3434377 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22970401  }} </ref>
*In 1970, Wilkinson described the typical skin eruption in glucagonoma as [[necrolytic migratory erythema]].<ref name="pmid22970401" />


==References==
==References==
{{reflist|2}}
{{reflist|2}}


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Latest revision as of 01:48, 27 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2], Mohammed Abdelwahed M.D[3]

Overview

Glucagonoma was first described in 1942 by Becker. In 1966, McGavran was the first to report a case of hyperglucagonemia associated with cutaneous changes. In 1970, Wilkinson described the typical skin eruption in glucagonoma as necrolytic migratory erythema.

Historical Perspective

References

  1. 1.0 1.1 Afsharfard A, Atqiaee K, Lotfollahzadeh S, Alborzi M, Derakhshanfar A (2012). "Necrolytic migratory erythema as the first manifestation of glucagonoma". Case Rep Surg. 2012: 974210. doi:10.1155/2012/974210. PMC 3434377. PMID 22970401.

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