Glucagonoma staging: Difference between revisions
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==Overview== | ==Overview== | ||
According to The American Joint Committee on Cancer (AJCC), there are four stages of glucagonoma based on the TNM staging | According to The American Joint Committee on Cancer (AJCC), there are four stages of glucagonoma based on the [[TNM staging system]]. | ||
==Staging== | ==Staging== | ||
According to The American Joint Committee on Cancer (AJCC), there are four stages of glucagonoma based on the TNM staging | According to The American Joint Committee on Cancer (AJCC), there are four stages of glucagonoma based on the [[TNM staging system]].<ref name="stage">Stage Information for Pancreatic Neuroendocrine Tumors (Islet Cell Tumors). http://www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq#section/_199</ref><ref name="pmid20180029">{{cite journal| author=Edge SB, Compton CC| title=The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM. | journal=Ann Surg Oncol | year= 2010 | volume= 17 | issue= 6 | pages= 1471-4 | pmid=20180029 | doi=10.1245/s10434-010-0985-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20180029 }}</ref> | ||
===TNM Classification=== | ===TNM Classification=== | ||
{| class="wikitable" | {| class="wikitable" | ||
! style="font-weight: bold;" | T | ! style="font-weight: bold;" | T | ||
! style="text-align: center; font-weight: bold;" | Primary Tumor | ! style="text-align: center; font-weight: bold;" | [[Primary Tumor]] | ||
|- | |- | ||
| style="font-weight: bold;" | Tx | | style="font-weight: bold;" | Tx | ||
| style="text-align: center;" | Primary tumor cannot be assessed | | style="text-align: center;" | Primary [[tumor]] cannot be assessed | ||
|- | |- | ||
| style="font-weight: bold;" | T0 | | style="font-weight: bold;" | T0 | ||
| style="text-align: center;" | No evidence of primary tumor | | style="text-align: center;" | No evidence of primary [[tumor]] | ||
|- | |- | ||
| style="font-weight: bold;" | Tis | | style="font-weight: bold;" | Tis | ||
| style="text-align: center;" | Carcinoma in situ | | style="text-align: center;" | [[Carcinoma in situ]] | ||
|- | |- | ||
| style="font-weight: bold;" | T1 | | style="font-weight: bold;" | T1 | ||
| style="text-align: center;" | Tumor limited to the pancreas, ≤2 cm in greatest dimension | | style="text-align: center;" | [[Tumor]] limited to the [[pancreas]], ≤2 cm in greatest dimension | ||
|- | |- | ||
| style="font-weight: bold;" | T2 | | style="font-weight: bold;" | T2 | ||
| style="text-align: center;" | Tumor limited to the pancreas, >2 cm in greatest dimension | | style="text-align: center;" | [[Tumor]] limited to the [[pancreas]], >2 cm in greatest dimension | ||
|- | |- | ||
| style="font-weight: bold;" | T3 | | style="font-weight: bold;" | T3 | ||
| style="text-align: center;" | Tumor extends beyond the pancreas but without involvement of the celiac axis or the superior mesenteric artery | | style="text-align: center;" | [[Tumor]] extends beyond the pancreas but without involvement of the celiac axis or the [[superior mesenteric artery]] | ||
|- | |- | ||
| style="font-weight: bold;" | T4 | | style="font-weight: bold;" | T4 | ||
| style="text-align: center;" | Tumor involves the celiac axis or the superior mesenteric artery (unresectable primary tumor) | | style="text-align: center;" | [[Tumor]] involves the [[celiac axis]] or the [[superior mesenteric artery]] (unresectable primary [[tumor]]) | ||
|} | |} | ||
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|- | |- | ||
| '''NX''' | | '''NX''' | ||
| Regional lymph nodes cannot be assessed | | Regional [[lymph nodes]] cannot be assessed | ||
|- | |- | ||
| '''N0''' | | '''N0''' | ||
| No regional lymph node metastasis | | No regional [[lymph node]] [[metastasis]] | ||
|- | |- | ||
| '''N1''' | | '''N1''' | ||
| Regional lymph node metastasis | | Regional [[lymph node]] metastasis | ||
|} | |} | ||
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|- | |- | ||
| style="font-weight: bold;" | M0 | | style="font-weight: bold;" | M0 | ||
| No distant metastasis | | No distant [[metastasis]] | ||
|- | |- | ||
| style="font-weight: bold;" | M1 | | style="font-weight: bold;" | M1 | ||
| Distant metastasis | | Distant [[metastasis]] | ||
|} | |} | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | |||
{{WS}} | |||
[[Category:Medicine]] | |||
[[Category:Endocrinology]] | |||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Gastroenterology]] | |||
[[Category:Surgery]] |
Latest revision as of 01:49, 27 November 2017
Glucagonoma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Glucagonoma staging On the Web |
American Roentgen Ray Society Images of Glucagonoma staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2], Mohammed Abdelwahed M.D[3]
Overview
According to The American Joint Committee on Cancer (AJCC), there are four stages of glucagonoma based on the TNM staging system.
Staging
According to The American Joint Committee on Cancer (AJCC), there are four stages of glucagonoma based on the TNM staging system.[1][2]
TNM Classification
T | Primary Tumor |
---|---|
Tx | Primary tumor cannot be assessed |
T0 | No evidence of primary tumor |
Tis | Carcinoma in situ |
T1 | Tumor limited to the pancreas, ≤2 cm in greatest dimension |
T2 | Tumor limited to the pancreas, >2 cm in greatest dimension |
T3 | Tumor extends beyond the pancreas but without involvement of the celiac axis or the superior mesenteric artery |
T4 | Tumor involves the celiac axis or the superior mesenteric artery (unresectable primary tumor) |
N | Regional Lymph Nodes |
---|---|
NX | Regional lymph nodes cannot be assessed |
N0 | No regional lymph node metastasis |
N1 | Regional lymph node metastasis |
M | Distant Metastases |
---|---|
M0 | No distant metastasis |
M1 | Distant metastasis |
Anatomic Stage/Prognostic Groups
Stage | T | N | M |
---|---|---|---|
0 | Tis | N0 | M0 |
IA | T1 | N0 | M0 |
IB | T2 | N0 | M0 |
IIA | T3 | N0 | M0 |
IIB | T1 | N1 | M0 |
T2 | N1 | M0 | |
T3 | N1 | M0 | |
III | T4 | Any N | M0 |
IV | Any T | Any N | M1 |
References
- ↑ Stage Information for Pancreatic Neuroendocrine Tumors (Islet Cell Tumors). http://www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq#section/_199
- ↑ Edge SB, Compton CC (2010). "The American Joint Committee on Cancer: the 7th edition of the AJCC cancer staging manual and the future of TNM". Ann Surg Oncol. 17 (6): 1471–4. doi:10.1245/s10434-010-0985-4. PMID 20180029.