Paraganglioma (patient information): Difference between revisions

	Paraganglioma
Overview
What are the symptoms?
What are the causes?
Who is at highest risk?
When to seek urgent medical care?
Diagnosis
Treatment options
Where to find medical care for Paraganglioma?
What to expect (Outlook/Prognosis)?
Possible complications
Paraganglioma On the Web
Ongoing Trials at Clinical Trials.gov
Images of Paraganglioma
Videos on Paraganglioma
FDA on Paraganglioma
CDC on Paraganglioma
Paraganglioma in the news
Blogs on Paraganglioma
Directions to Hospitals Treating Paraganglioma
Risk calculators and risk factors for Paraganglioma

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Latest revision as of 15:04, 27 November 2017

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Jinhui Wu, MD; Varun Kumar, M.B.B.S.

Overview

Paraganglioma also known as glomus jugulare tumor is a tumor of a part of the temporal bone in the skull. This tumor can affect the ear, upper neck, base of the skull, and the surrounding blood vessels and nerves.

What are the symptoms of Paraganglioma?

Difficulty swallowing (dysphagia)
Dizziness
Hearing problems or loss
Hearing pulsations in the ear
Hoarseness
Pain
Weakness or loss of movement in the face (facial nerve palsy)

What causes Paraganglioma?

The cause of a paraganglioma is unknown.

Who is at highest risk?

Usually, there are no known risk factors. Paraganglioma have been associated with changes (mutations) in a gene responsible for the enzyme succinate dehydrogenase (SDHD).

When to seek urgent medical care?

Call your health care provider if you:

Are having difficulty with hearing or swallowing
Develop pulsations in your ear
Notice a lump in your neck
Notice any problems with the muscles in your face

Diagnosis

Paraganglioma are diagnosed by physical examination and various scans, including:

Treatment options

Paraganglioma are rarely cancerous and do not tend to spread to other parts of the body. However, treatment may be needed to relieve symptoms. The main treatment is surgery. Surgery is complex and is usually done by both a neurosurgeon and a head and neck surgeon (neurotologist).

In some cases, a procedure called embolization is performed before surgery to prevent the tumor from bleeding too much during surgery.

After surgery, radiation therapy may be used to treat any part of the tumor that could not be removed completely.

Some glomus tumors can be treated with stereotactic radiosurgery.

Where to find medical care for Paraganglioma?

Directions to Hospitals Treating paraganglioma

What to expect (Outlook/Prognosis)?

Patients who have surgery or radiation tend to do well. More than 90% of those with paraganglioma are cured.

Possible complications

The most common complications are due to nerve damage, which may be caused by the tumor itself or damage during surgery. Nerve damage can lead to:

Change in voice
Difficulty swallowing
Hearing loss
Paralysis of the face

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+__NOTOC__
 '''For the WikiDoc page for this topic, click [[Paraganglioma|here]]'''
-{{SI}}
+{{Paraganglioma (patient information)}}
-'''Editor-in-Chief:''' Jinhui Wu, MD
+{{CMG}};  '''Associate Editor(s)-In-Chief:''' Jinhui Wu, MD; [[Varun Kumar, M.B.B.S.]]
-{{EJ}}
+==Overview==
+Paraganglioma also known as glomus jugulare tumor is a tumor of a part of the temporal bone in the skull. This tumor can affect the ear, upper neck, base of the skull, and the surrounding blood vessels and nerves.
-==Overview of paraganglioma==
+==What are the symptoms of Paraganglioma?==
-Paraganglioma is a rare benign tumor that origins from cells of the paraganglia. Paraganglia are a collection of cells that came from embryonic nervous tissue and are found in the abdomen, chest, head and neck areas. The tumors are divided into adrenal paragangliomas or [[pheochromocytomas]] and extra-adrenal paragangliomas. Symptoms may vary depending on the exact location of the tumor. Usual symptoms include [[hypertension]], [[palpitation]], [[headache]], [[sweat]], neck mass, cranial nerve palsies, [[tinnitus]], [[hearing loss]], swallowing difficulty, reddish bulge behind eardrum, [[Brown's sign]], [[dysphagia]], [[hoarseness]], etc. Diagnostic tests involve blood and/or urine level of catecholamines  and its metabolites, imaging tests such ultrasound, computed tomograph scan, magnetic resonance image scan. Treatments are [[surgery]], [[radiation therapy]] and [[embolization]].
+*Difficulty swallowing (dysphagia)
+*Dizziness
+*Hearing problems or loss
+*Hearing pulsations in the ear
+*Hoarseness
+*Pain
+*Weakness or loss of movement in the face (facial nerve palsy)
-==Where to find medical care for paraganglioma?==
+==What causes Paraganglioma?==
+The cause of a paraganglioma is unknown.
+==Who is at highest risk?==
+Usually, there are no known risk factors. Paraganglioma have been associated with changes (mutations) in a gene responsible for the enzyme succinate dehydrogenase (SDHD).
+==When to seek urgent medical care?==
+Call your health care provider if you:
+*Are having difficulty with hearing or swallowing
+*Develop pulsations in your ear
+*Notice a lump in your neck
+*Notice any problems with the muscles in your face
+==Diagnosis==
+Paraganglioma are diagnosed by physical examination and various scans, including:
+*[[Cerebral angiography]]
+*[[CT scan]]
+*[[MRI scan]]
+==Treatment options==
+Paraganglioma are rarely cancerous and do not tend to spread to other parts of the body. However, treatment may be needed to relieve symptoms. The main treatment is surgery. Surgery is complex and is usually done by both a neurosurgeon and a head and neck surgeon (neurotologist).
+In some cases, a procedure called embolization is performed before surgery to prevent the tumor from bleeding too much during surgery.
+After surgery, radiation therapy may be used to treat any part of the tumor that could not be removed completely.
+Some glomus tumors can be treated with stereotactic radiosurgery.
+==Where to find medical care for Paraganglioma?==
 [http://maps.google.com/maps?f=q&amp;hl=en&amp;geocode=&amp;q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|paraganglioma}}}}&amp;sll=37.0625,-95.677068&amp;sspn=65.008093,112.148438&amp;ie=UTF8&amp;ll=37.0625,-95.677068&amp;spn=91.690419,149.414063&amp;z=2&amp;source=embed Directions to Hospitals Treating paraganglioma]
-==Copyleft Sources==
+==What to expect (Outlook/Prognosis)?==
-http://www.cancer.gov/dictionary/?CdrID=390305
+Patients who have surgery or radiation tend to do well. More than 90% of those with paraganglioma are cured.
-http://www.utmb.edu/otoref/Grnds/paragang-9812/paragang-9812.html
+==Possible complications==
+The most common complications are due to nerve damage, which may be caused by the tumor itself or damage during surgery. Nerve damage can lead to:
+*Change in voice
+*Difficulty swallowing
+*Hearing loss
+*Paralysis of the face
-http://www.wrongdiagnosis.com/p/paraganglioma/basics.htm
 {{WH}}
 {{WS}}
-[[Category:Patient Information]]
+[[Category:Patient information]]
+[[Category:Oncology patient information]]
+[[Category:Neurology]]
+[[Category:Neurology patient information]]
+[[Category:Disease]]
+[[Category:Types of cancer]]
+[[Category:Mature chapter]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Orthopedics]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]
+[[Category:Neurology]]
+[[Category:Neurosurgery]]