Primary central nervous system lymphoma screening: Difference between revisions

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{{CMG}}
__NOTOC__
{{Primary central nervous system lymphoma}}
{{Primary central nervous system lymphoma}}
{{CMG}}{{AE}}{{SR}}
==Overview==
==Overview==
'''Primary CNS lymphoma''' is a [[brain tumor|primary intracranial tumor]] usually present in those with severe immunosuppression --- commonly in those with [[AIDS]] --- and represents around 20% of all cases of lymphomas in HIV infection (other types being [[Burkitt's lymphoma]] and immunoblastic lymphoma). Primary CNS lymphoma (PCNSL) is highly associated with [[Epstein-Barr virus]] infection (> 90%) in immunodeficient patients<ref>Fine HA, Mayer RJ. Primary central nervous system lymphoma. ''Ann Intern Med'' 1993; 119(11):1093-1104</ref> (such as those with AIDS and those iatrogenically immunosupressed) and does not have predilections for any age group. Mean [[CD4]]+ count at time of diagnosis is ~50/uL. Because of the severity of immunosuppression at the time of diagnosis, it is to no surprise that prognosis is usually poor. In immunocompetent patients (that is, patients that do not have AIDS or some other immunodeficiency) there is rarely an association with EBV infection or other infectious DNAs. In the immunocompetent population, PCNSL typically affects older patients in their 50's and 60's.
There is insufficient evidence to recommend routine screening for primary central nervous system lymphoma.<ref name=screeningofcentralnervoussystemlymphoma1>Screening of primary central nervous system lymphoma. U.S. preventive services task force 2016. http://www.uspreventiveservicestaskforce.org/BrowseRec/Search?s=PRIMARY+CENTRAL+NERVOUS+SYSTEM+LYMPHOMA. Accessed on February 24, 2016</ref>
 
==Screening==
==Screening==
There is insufficient evidence to recommend routine screening for primary central nervous system lymphoma.<ref name=screeningofcentralnervoussystemlymphoma1>Screening of primary central nervous system lymphoma. U.S. preventive services task force 2016. http://www.uspreventiveservicestaskforce.org/BrowseRec/Search?s=PRIMARY+CENTRAL+NERVOUS+SYSTEM+LYMPHOMA. Accessed on February 24, 2016</ref>
==References==
==References==
<references/>
{{Reflist|2}}
 
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Latest revision as of 15:14, 27 November 2017

Primary central nervous system lymphoma Microchapters

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Overview

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Differentiating Primary Central Nervous System Lymphoma from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

There is insufficient evidence to recommend routine screening for primary central nervous system lymphoma.[1]

Screening

There is insufficient evidence to recommend routine screening for primary central nervous system lymphoma.[1]

References

  1. ↑ 1.0 1.1 Screening of primary central nervous system lymphoma. U.S. preventive services task force 2016. http://www.uspreventiveservicestaskforce.org/BrowseRec/Search?s=PRIMARY+CENTRAL+NERVOUS+SYSTEM+LYMPHOMA. Accessed on February 24, 2016


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