Tumor lysis syndrome diagnostic criteria: Difference between revisions
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==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
The diagnosis of tumor lysis syndrome is based on the Cairo–Bishop criteria:<ref name="pmid15384972">{{cite journal| author=Cairo MS, Bishop M| title=Tumour lysis syndrome: new therapeutic strategies and classification. | journal=Br J Haematol | year= 2004 | volume= 127 | issue= 1 | pages= 3-11 | pmid=15384972 | doi=10.1111/j.1365-2141.2004.05094.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15384972}}</ref> | The diagnosis of tumor lysis syndrome is based on the Cairo–Bishop criteria:<ref name="pmid15384972">{{cite journal| author=Cairo MS, Bishop M| title=Tumour lysis syndrome: new therapeutic strategies and classification. | journal=Br J Haematol | year= 2004 | volume= 127 | issue= 1 | pages= 3-11 | pmid=15384972 | doi=10.1111/j.1365-2141.2004.05094.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15384972}}</ref> | ||
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Laboratory tumor lysis syndrome | |||
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*Abnormality in two or more of the following within 3 days before or 7 days after starting chemotherapy: | |||
:*[[Hyperuricemia]] ≥ 476 μmol/l | :*[[Hyperuricemia]] ≥ 476 μmol/l | ||
:*[[Hyperphosphatemia]] ≥ 2·1 mmol/l (children), x ≥1·45 mmol/l (adults) | :*[[Hyperphosphatemia]] ≥ 2·1 mmol/l (children), x ≥1·45 mmol/l (adults) | ||
:*[[Hyperkalemia]] ≥ 6·0 mmol/l | :*[[Hyperkalemia]] ≥ 6·0 mmol/l | ||
:*[[Hypocalcemia]] ≤ 1·75 mmol/l | :*[[Hypocalcemia]] ≤ 1·75 mmol/l | ||
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Clinical tumor lysis syndrome | |||
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*Laboratory tumor lysis syndrome plus one or more of the following: | |||
:*Increase serum [[creatinine]] (1.5 times upper normal limit) | :*Increase serum [[creatinine]] (1.5 times upper normal limit) | ||
:*[[Cardiac arrhythmia]] | :*[[Cardiac arrhythmia]] | ||
:*[[Sudden death]] | :*[[Sudden death]] | ||
:*[[Seizure]] | :*[[Seizure]] | ||
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==References== | ==References== | ||
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[[Category:Blood]] | [[Category:Blood]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] |
Latest revision as of 17:25, 27 November 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
The diagnosis of tumor lysis syndrome is based on the Cairo–Bishop criteria, which includes uric acid, potassium, phosphorous, and calcium.[1]
Diagnostic Criteria
The diagnosis of tumor lysis syndrome is based on the Cairo–Bishop criteria:[1]
Category | Diagnostic criteria |
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Laboratory tumor lysis syndrome |
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Clinical tumor lysis syndrome |
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References
- ↑ 1.0 1.1 Cairo MS, Bishop M (2004). "Tumour lysis syndrome: new therapeutic strategies and classification". Br J Haematol. 127 (1): 3–11. doi:10.1111/j.1365-2141.2004.05094.x. PMID 15384972.