Primary sclerosing cholangitis surgery: Difference between revisions
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==Overview== | ==Overview== | ||
Primary sclerosing cholangitis is a progressive disease that ultimately leads to [[end-stage liver disease]] ([[ESLD]]). Endoscopic management can be targeted for dominant strictures or as [[palliative]] treatment. However, current gold standard of treatment for primary sclerosing cholangitis is [[liver transplantation]]. Despite [[liver transplantation]], disease may still recur in 25% of patients. | |||
==Surgery== | ==Surgery== | ||
Primary sclerosing cholangitis is a progressive disease that ultimately leads to [[end | * Primary sclerosing cholangitis is a progressive disease that ultimately leads to [[End stage liver failure|end stage liver disease]] ([[End stage liver failure|ESLD]]). | ||
* [[Endoscopy|Endoscopic]] management can be targeted for dominant strictures or as [[palliative]] treatment; however, current gold standard of treatment for primary sclerosing cholangitis is [[liver transplantation]]. | |||
** Despite [[liver transplantation]], disease may still recur in 25% of patients.<ref name="pmid27653566">{{cite journal |vauthors=Lazaridis KN, LaRusso NF |title=Primary Sclerosing Cholangitis |journal=N. Engl. J. Med. |volume=375 |issue=12 |pages=1161–70 |year=2016 |pmid=27653566 |doi=10.1056/NEJMra1506330 |url=}}</ref><ref name="pmid17037993">{{cite journal |vauthors=Tischendorf JJ, Hecker H, Krüger M, Manns MP, Meier PN |title=Characterization, outcome, and prognosis in 273 patients with primary sclerosing cholangitis: A single center study |journal=Am. J. Gastroenterol. |volume=102 |issue=1 |pages=107–14 |year=2007 |pmid=17037993 |doi=10.1111/j.1572-0241.2006.00872.x |url=}}</ref><ref name="pmid22228965">{{cite journal |vauthors=Fosby B, Karlsen TH, Melum E |title=Recurrence and rejection in liver transplantation for primary sclerosing cholangitis |journal=World J. Gastroenterol. |volume=18 |issue=1 |pages=1–15 |year=2012 |pmid=22228965 |pmc=3251800 |doi=10.3748/wjg.v18.i1.1 |url=}}</ref> | |||
==References== | ==References== | ||
Latest revision as of 16:51, 6 December 2017
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Primary sclerosing cholangitis Microchapters |
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Differentiating Primary sclerosing cholangitis from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Primary sclerosing cholangitis surgery On the Web |
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American Roentgen Ray Society Images of Primary sclerosing cholangitis surgery |
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Directions to Hospitals Treating Primary sclerosing cholangitis |
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Risk calculators and risk factors for Primary sclerosing cholangitis surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Primary sclerosing cholangitis is a progressive disease that ultimately leads to end-stage liver disease (ESLD). Endoscopic management can be targeted for dominant strictures or as palliative treatment. However, current gold standard of treatment for primary sclerosing cholangitis is liver transplantation. Despite liver transplantation, disease may still recur in 25% of patients.
Surgery
- Primary sclerosing cholangitis is a progressive disease that ultimately leads to end stage liver disease (ESLD).
- Endoscopic management can be targeted for dominant strictures or as palliative treatment; however, current gold standard of treatment for primary sclerosing cholangitis is liver transplantation.
- Despite liver transplantation, disease may still recur in 25% of patients.[1][2][3]
References
- ↑ Lazaridis KN, LaRusso NF (2016). "Primary Sclerosing Cholangitis". N. Engl. J. Med. 375 (12): 1161–70. doi:10.1056/NEJMra1506330. PMID 27653566.
- ↑ Tischendorf JJ, Hecker H, Krüger M, Manns MP, Meier PN (2007). "Characterization, outcome, and prognosis in 273 patients with primary sclerosing cholangitis: A single center study". Am. J. Gastroenterol. 102 (1): 107–14. doi:10.1111/j.1572-0241.2006.00872.x. PMID 17037993.
- ↑ Fosby B, Karlsen TH, Melum E (2012). "Recurrence and rejection in liver transplantation for primary sclerosing cholangitis". World J. Gastroenterol. 18 (1): 1–15. doi:10.3748/wjg.v18.i1.1. PMC 3251800. PMID 22228965.