TROVE2: Difference between revisions

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{{Infobox_gene}}
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'''60 kDa SS-A/Ro ribonucleoprotein''' is a [[protein]] that in humans is encoded by the ''TROVE2'' [[gene]].<ref name="pmid8188321">{{cite journal |vauthors=Frank MB, Mattei MG | title = Mapping of the human 60,000 M(r) Ro/SSA locus: the genes for three Ro/SSA autoantigens are located on separate chromosomes | journal = Immunogenetics | volume = 39 | issue = 6 | pages = 428–31 |date=Jun 1994 | pmid = 8188321 | pmc =  | doi =  10.1007/bf00176161}}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TROVE2 TROVE domain family, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6738| accessdate = }}</ref>
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = TROVE domain family, member 2
| HGNCid = 11313
| Symbol = TROVE2
| AltSymbols =; SSA2
| OMIM = 600063
| ECnumber =
| Homologene = 3383
| MGIid = 106652
  | GeneAtlas_image1 = PBB_GE_TROVE2_212852_s_at_tn.png
  | GeneAtlas_image2 = PBB_GE_TROVE2_207520_at_tn.png
| GeneAtlas_image3 = PBB_GE_TROVE2_210438_x_at_tn.png
| Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0004618 |text = phosphoglycerate kinase activity}}
| Component = {{GNF_GO|id=GO:0030529 |text = ribonucleoprotein complex}}
| Process = {{GNF_GO|id=GO:0006096 |text = glycolysis}} {{GNF_GO|id=GO:0006383 |text = transcription from RNA polymerase III promoter}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6738
    | Hs_Ensembl = ENSG00000116747
    | Hs_RefseqProtein = NP_001035828
    | Hs_RefseqmRNA = NM_001042369
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 191295787
    | Hs_GenLoc_end = 191327530
    | Hs_Uniprot = P10155
    | Mm_EntrezGene = 20822
    | Mm_Ensembl = ENSMUSG00000018199
    | Mm_RefseqmRNA = NM_013835
    | Mm_RefseqProtein = NP_038863
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 145517790
    | Mm_GenLoc_end = 145539196
    | Mm_Uniprot = Q3TJ75
  }}
}}
'''TROVE domain family, member 2''', also known as '''TROVE2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TROVE2 TROVE domain family, member 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6738| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist|30em}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=James JA, Dickey WD, Fujisaku A, ''et al.'' |title=Antigenicity of a recombinant Ro (SS-A) fusion protein. |journal=Arthritis Rheum. |volume=33 |issue= 1 |pages= 102-6 |year= 1990 |pmid= 1689160 |doi= }}
*{{cite journal  | author=James JA |title=Antigenicity of a recombinant Ro (SS-A) fusion protein |journal=Arthritis Rheum. |volume=33 |issue= 1 |pages= 102–6 |year= 1990 |pmid= 1689160 |doi=10.1002/art.1780330114 |name-list-format=vanc| author2=Dickey WD  | author3=Fujisaku A  | display-authors=3  | last4=O'Brien  | first4=Charles A. | last5=Deutscher  | first5=Susan L.  | last6=Keene  | first6=Jack D.  | last7=Harley  | first7=John B. }}
*{{cite journal | author=Jitsukawa T, Nakajima S, Usui J, Watanabe H |title=Detection of anti-nuclear antibodies from patients with systemic rheumatic diseases by ELISA using HEp-2 cell nuclei. |journal=J. Clin. Lab. Anal. |volume=5 |issue= 1 |pages= 49-53 |year= 1991 |pmid= 1999763 |doi=  }}
*{{cite journal  |vauthors=Jitsukawa T, Nakajima S, Usui J, Watanabe H |title=Detection of anti-nuclear antibodies from patients with systemic rheumatic diseases by ELISA using HEp-2 cell nuclei |journal=J. Clin. Lab. Anal. |volume=5 |issue= 1 |pages= 49–53 |year= 1991 |pmid= 1999763 |doi=10.1002/jcla.1860050109 }}
*{{cite journal  | author=Ben-Chetrit E, Gandy BJ, Tan EM, Sullivan KF |title=Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen. |journal=J. Clin. Invest. |volume=83 |issue= 4 |pages= 1284-92 |year= 1989 |pmid= 2649513 |doi=  }}
*{{cite journal  |vauthors=Ben-Chetrit E, Gandy BJ, Tan EM, Sullivan KF |title=Isolation and characterization of a cDNA clone encoding the 60-kD component of the human SS-A/Ro ribonucleoprotein autoantigen |journal=J. Clin. Invest. |volume=83 |issue= 4 |pages= 1284–92 |year= 1989 |pmid= 2649513 |doi=10.1172/JCI114013  | pmc=303819 }}
*{{cite journal  | author=Deutscher SL, Harley JB, Keene JD |title=Molecular analysis of the 60-kDa human Ro ribonucleoprotein. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 24 |pages= 9479-83 |year= 1989 |pmid= 3200833 |doi=  }}
*{{cite journal  |vauthors=Deutscher SL, Harley JB, Keene JD |title=Molecular analysis of the 60-kDa human Ro ribonucleoprotein |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 24 |pages= 9479–83 |year= 1989 |pmid= 3200833 |doi=10.1073/pnas.85.24.9479  | pmc=282776 }}
*{{cite journal  | author=Lee LA, Harmon CE, Huff JC, ''et al.'' |title=The demonstration of SS-A/Ro antigen in human fetal tissues and in neonatal and adult skin. |journal=J. Invest. Dermatol. |volume=85 |issue= 2 |pages= 143-6 |year= 1985 |pmid= 3926904 |doi=  }}
*{{cite journal  | author=Lee LA |title=The demonstration of SS-A/Ro antigen in human fetal tissues and in neonatal and adult skin |journal=J. Invest. Dermatol. |volume=85 |issue= 2 |pages= 143–6 |year= 1985 |pmid= 3926904 |doi=10.1111/1523-1747.ep12276566 |name-list-format=vanc| author2=Harmon CE | author3=Huff JC  | display-authors=3  | last4=Norris  | first4=David A. | last5=Weston  | first5=William L. }}
*{{cite journal  | author=Wolin SL, Steitz JA |title=The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 7 |pages= 1996-2000 |year= 1984 |pmid= 6201849 |doi= }}
*{{cite journal  |vauthors=Wolin SL, Steitz JA |title=The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 7 |pages= 1996–2000 |year= 1984 |pmid= 6201849 |doi=10.1073/pnas.81.7.1996 | pmc=345423  }}
*{{cite journal | author=Harmon CE, Deng JS, Peebles CL, Tan EM |title=The importance of tissue substrate in the SS-A/Ro antigen-antibody system. |journal=Arthritis Rheum. |volume=27 |issue= 2 |pages= 166-73 |year= 1984 |pmid= 6421292 |doi=  }}
*{{cite journal  |vauthors=Harmon CE, Deng JS, Peebles CL, Tan EM |title=The importance of tissue substrate in the SS-A/Ro antigen-antibody system |journal=Arthritis Rheum. |volume=27 |issue= 2 |pages= 166–73 |year= 1984 |pmid= 6421292 |doi=10.1002/art.1780270207  }}
*{{cite journal  | author=Fritzler MJ, Miller BJ |title=Detection of autoantibodies to SS-A/Ro by indirect immunofluorescence using a transfected and overexpressed human 60 kD Ro autoantigen in HEp-2 cells. |journal=J. Clin. Lab. Anal. |volume=9 |issue= 3 |pages= 218-24 |year= 1995 |pmid= 7602431 |doi=  }}
*{{cite journal  |vauthors=Fritzler MJ, Miller BJ |title=Detection of autoantibodies to SS-A/Ro by indirect immunofluorescence using a transfected and overexpressed human 60 kD Ro autoantigen in HEp-2 cells |journal=J. Clin. Lab. Anal. |volume=9 |issue= 3 |pages= 218–24 |year= 1995 |pmid= 7602431 |doi=10.1002/jcla.1860090312 }}
*{{cite journal  | author=Chan EK, Tan EM, Ward DC, Matera AG |title=Human 60-kDa SS-A/Ro ribonucleoprotein autoantigen gene (SSA2) localized to 1q31 by fluorescence in situ hybridization. |journal=Genomics |volume=23 |issue= 1 |pages= 298-300 |year= 1995 |pmid= 7829096 |doi= 10.1006/geno.1994.1502 }}
*{{cite journal  |vauthors=Chan EK, Tan EM, Ward DC, Matera AG |title=Human 60-kDa SS-A/Ro ribonucleoprotein autoantigen gene (SSA2) localized to 1q31 by fluorescence in situ hybridization |journal=Genomics |volume=23 |issue= 1 |pages= 298–300 |year= 1995 |pmid= 7829096 |doi= 10.1006/geno.1994.1502 }}
*{{cite journal  | author=Frank MB, Mattei MG |title=Mapping of the human 60,000 M(r) Ro/SSA locus: the genes for three Ro/SSA autoantigens are located on separate chromosomes. |journal=Immunogenetics |volume=39 |issue= 6 |pages= 428-31 |year= 1994 |pmid= 8188321 |doi=  }}
*{{cite journal  |vauthors=Wang D, Buyon JP, Zhu W, Chan EK |title=Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies |journal=J. Clin. Invest. |volume=104 |issue= 9 |pages= 1265–75 |year= 1999 |pmid= 10545525 |doi=10.1172/JCI8003  | pmc=409828 }}
*{{cite journal  | author=Wang D, Buyon JP, Zhu W, Chan EK |title=Defining a novel 75-kDa phosphoprotein associated with SS-A/Ro and identification of distinct human autoantibodies. |journal=J. Clin. Invest. |volume=104 |issue= 9 |pages= 1265-75 |year= 1999 |pmid= 10545525 |doi= }}
*{{cite journal  | author=Kurien BT |title=Autoantibody to the leucine zipper region of 52 kDa Ro/SSA binds native 60 kDa Ro/SSA: identification of a tertiary epitope with components from 60 kDa Ro/SSA and 52 kDa Ro/SSA |journal=Scand. J. Immunol. |volume=53 |issue= 3 |pages= 268–76 |year= 2001 |pmid= 11251884 |doi=10.1046/j.1365-3083.2001.00870.x |name-list-format=vanc| author2=Chambers TL  | author3=Thomas PY  | display-authors=3  | last4=Frank  | first4=M. B.  | last5=Scofield  | first5=R. H.  }}
*{{cite journal  | author=Kurien BT, Chambers TL, Thomas PY, ''et al.'' |title=Autoantibody to the leucine zipper region of 52 kDa Ro/SSA binds native 60 kDa Ro/SSA: identification of a tertiary epitope with components from 60 kDa Ro/SSA and 52 kDa Ro/SSA. |journal=Scand. J. Immunol. |volume=53 |issue= 3 |pages= 268-76 |year= 2001 |pmid= 11251884 |doi=  }}
*{{cite journal | author=Fouraux MA |title=Nucleolin associates with a subset of the human Ro ribonucleoprotein complexes |journal=J. Mol. Biol. |volume=320 |issue= 3 |pages= 475–88 |year= 2002 |pmid= 12096904 |doi=10.1016/S0022-2836(02)00518-1 |name-list-format=vanc| author2=Bouvet P  | author3=Verkaart S  | display-authors=3  | last4=Van Venrooij  | first4=Walther J. | last5=Pruijn  | first5=Ger J.M. }}
*{{cite journal  | author=Fouraux MA, Bouvet P, Verkaart S, ''et al.'' |title=Nucleolin associates with a subset of the human Ro ribonucleoprotein complexes. |journal=J. Mol. Biol. |volume=320 |issue= 3 |pages= 475-88 |year= 2002 |pmid= 12096904 |doi=  }}
*{{cite journal  | author=McArthur C |title=Intracellular trafficking and surface expression of SS-A (Ro), SS-B (La), poly(ADP-ribose) polymerase and alpha-fodrin autoantigens during apoptosis in human salivary gland cells induced by tumour necrosis factor-alpha |journal=Arch. Oral Biol. |volume=47 |issue= 6 |pages= 443–8 |year= 2002 |pmid= 12102760 |doi=10.1016/S0003-9969(02)00025-0 |name-list-format=vanc| author2=Wang Y  | author3=Veno P  | display-authors=3  | last4=Zhang  | first4=J  | last5=Fiorella  | first5=R  }}
*{{cite journal  | author=McArthur C, Wang Y, Veno P, ''et al.'' |title=Intracellular trafficking and surface expression of SS-A (Ro), SS-B (La), poly(ADP-ribose) polymerase and alpha-fodrin autoantigens during apoptosis in human salivary gland cells induced by tumour necrosis factor-alpha. |journal=Arch. Oral Biol. |volume=47 |issue= 6 |pages= 443-8 |year= 2002 |pmid= 12102760 |doi= }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Belisova A |title=RNA chaperone activity of protein components of human Ro RNPs |journal=RNA |volume=11 |issue= 7 |pages= 1084–94 |year= 2005 |pmid= 15928345 |doi= 10.1261/rna.7263905  | pmc=1370793  |name-list-format=vanc| author2=Semrad K  | author3=Mayer O  | display-authors=3  | last4=Kocian  | first4=G  | last5=Waigmann  | first5=E  | last6=Schroeder  | first6=R  | last7=Steiner  | first7=G }}
*{{cite journal | author=Belisova A, Semrad K, Mayer O, ''et al.'' |title=RNA chaperone activity of protein components of human Ro RNPs. |journal=RNA |volume=11 |issue= 7 |pages= 1084-94 |year= 2005 |pmid= 15928345 |doi= 10.1261/rna.7263905 }}
*{{cite journal  | author=Hennig J |title=Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52 |journal=J. Biol. Chem. |volume=280 |issue= 39 |pages= 33250–61 |year= 2005 |pmid= 15964842 |doi= 10.1074/jbc.M503066200  |name-list-format=vanc| author2=Ottosson L  | author3=Andrésen C  | display-authors=3  | last4=Horvath  | first4=L  | last5=Kuchroo  | first5=VK  | last6=Broo  | first6=K  | last7=Wahren-Herlenius  | first7=M  | last8=Sunnerhagen  | first8=M }}
*{{cite journal  | author=Hennig J, Ottosson L, Andrésen C, ''et al.'' |title=Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52. |journal=J. Biol. Chem. |volume=280 |issue= 39 |pages= 33250-61 |year= 2005 |pmid= 15964842 |doi= 10.1074/jbc.M503066200 }}
*{{cite journal  | author=Gregory SG |title=The DNA sequence and biological annotation of human chromosome 1 |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727  |name-list-format=vanc| author2=Barlow KF  | author3=McLay KE  | display-authors=3  | last4=Kaul  | first4=R.  | last5=Swarbreck  | first5=D.  | last6=Dunham  | first6=A.  | last7=Scott  | first7=C. E.  | last8=Howe  | first8=K. L.  | last9=Woodfine  | first9=K. }}
*{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
*{{cite journal  | author=Ewing RM |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134  | pmc=1847948  |name-list-format=vanc| author2=Chu P  | author3=Elisma F  | display-authors=3  | last4=Li  | first4=Hongyan  | last5=Taylor  | first5=Paul  | last6=Climie  | first6=Shane  | last7=McBroom-Cerajewski  | first7=Linda  | last8=Robinson  | first8=Mark D  | last9=O'Connor | first9=Liam }}
*{{cite journal | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
}}
* {{Cite news|url=http://www.sci-news.com/genetics/link-immune-system-memory-brain-04816.html|title=Scientists Find Link between Immune System, Memory and Structure of Brain {{!}} Genetics, Neuroscience {{!}} Sci-News.com|work=Breaking Science News {{!}} Sci-News.com|access-date=2017-05-01|language=en-US}}
{{refend}}
{{refend}}


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Latest revision as of 12:19, 15 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

60 kDa SS-A/Ro ribonucleoprotein is a protein that in humans is encoded by the TROVE2 gene.[1][2]


References

  1. ↑ Frank MB, Mattei MG (Jun 1994). "Mapping of the human 60,000 M(r) Ro/SSA locus: the genes for three Ro/SSA autoantigens are located on separate chromosomes". Immunogenetics. 39 (6): 428–31. doi:10.1007/bf00176161. PMID 8188321.
  2. ↑ "Entrez Gene: TROVE2 TROVE domain family, member 2".

Further reading


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