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{{Underlinked|date=March 2014}}
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{{Infobox_gene}}
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'''Trafficking protein particle complex subunit 3''' is a [[protein]] that in humans is encoded by the ''TRAPPC3'' [[gene]].<ref name="pmid8619474">{{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Anal Biochem | volume = 236 | issue = 1 | pages = 107–13 |date=Jun 1996 | pmid = 8619474 | pmc =  | doi = 10.1006/abio.1996.0138 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TRAPPC3 trafficking protein particle complex 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27095| accessdate = }}</ref>
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{{GNF_Protein_box
| image = PBB_Protein_TRAPPC3_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1sz7.
| PDB = {{PDB2|1sz7}}, {{PDB2|1wc8}}, {{PDB2|1wc9}}, {{PDB2|2c0j}}, {{PDB2|2cfh}}, {{PDB2|2j3r}}, {{PDB2|2j3t}}, {{PDB2|2j3w}}, {{PDB2|2pwn}}
| Name = Trafficking protein particle complex 3
| HGNCid = 19942
| Symbol = TRAPPC3
| AltSymbols =; BET3
| OMIM =
| ECnumber =
| Homologene = 6399
| MGIid = 1351486
  | GeneAtlas_image1 = PBB_GE_TRAPPC3_203511_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_TRAPPC3_203512_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0000139 |text = Golgi membrane}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005829 |text = cytosol}}
| Process = {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0006888 |text = ER to Golgi vesicle-mediated transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 27095
    | Hs_Ensembl = ENSG00000054116
    | Hs_RefseqProtein = NP_055223
    | Hs_RefseqmRNA = NM_014408
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 36374760
    | Hs_GenLoc_end = 36387685
    | Hs_Uniprot = O43617
    | Mm_EntrezGene = 27096
    | Mm_Ensembl = ENSMUSG00000028847
    | Mm_RefseqmRNA = XM_990561
    | Mm_RefseqProtein = XP_995655
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 125764709
    | Mm_GenLoc_end = 125778187
    | Mm_Uniprot = Q3U9K9
  }}
}}
'''Trafficking protein particle complex 3''', also known as '''TRAPPC3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TRAPPC3 trafficking protein particle complex 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27095| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
*{{cite journal   |vauthors=Yu W, Andersson B, Worley KC, etal |title=Large-Scale Concatenation cDNA Sequencing |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146 }}
*{{cite journal  | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
*{{cite journal   |vauthors=Sacher M, Jiang Y, Barrowman J, etal |title=TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion |journal=EMBO J. |volume=17 |issue= 9 |pages= 2494–503 |year= 1998 |pmid= 9564032 |doi= 10.1093/emboj/17.9.2494 | pmc=1170591 }}
*{{cite journal | author=Sacher M, Jiang Y, Barrowman J, ''et al.'' |title=TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. |journal=EMBO J. |volume=17 |issue= 9 |pages= 2494-503 |year= 1998 |pmid= 9564032 |doi= 10.1093/emboj/17.9.2494 }}
*{{cite journal  | vauthors=Barrowman J, Sacher M, Ferro-Novick S |title=TRAPP stably associates with the Golgi and is required for vesicle docking |journal=EMBO J. |volume=19 |issue= 5 |pages= 862–9 |year= 2000 |pmid= 10698928 |doi= 10.1093/emboj/19.5.862 | pmc=305626 }}
*{{cite journal  | author=Barrowman J, Sacher M, Ferro-Novick S |title=TRAPP stably associates with the Golgi and is required for vesicle docking. |journal=EMBO J. |volume=19 |issue= 5 |pages= 862-9 |year= 2000 |pmid= 10698928 |doi= 10.1093/emboj/19.5.862 }}
*{{cite journal   |vauthors=Gavin AC, Bösche M, Krause R, etal |title=Functional organization of the yeast proteome by systematic analysis of protein complexes |journal=Nature |volume=415 |issue= 6868 |pages= 141–7 |year= 2002 |pmid= 11805826 |doi= 10.1038/415141a }}
*{{cite journal | author=Gavin AC, Bösche M, Krause R, ''et al.'' |title=Functional organization of the yeast proteome by systematic analysis of protein complexes. |journal=Nature |volume=415 |issue= 6868 |pages= 141-7 |year= 2002 |pmid= 11805826 |doi= 10.1038/415141a }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Kim YG, Sohn EJ, Seo J, etal |title=Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP |journal=Nat. Struct. Mol. Biol. |volume=12 |issue= 1 |pages= 38–45 |year= 2005 |pmid= 15608655 |doi= 10.1038/nsmb871 }}
*{{cite journal | author=Kim YG, Sohn EJ, Seo J, ''et al.'' |title=Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP. |journal=Nat. Struct. Mol. Biol. |volume=12 |issue= 1 |pages= 38-45 |year= 2005 |pmid= 15608655 |doi= 10.1038/nsmb871 }}
*{{cite journal   |vauthors=Turnbull AP, Kümmel D, Prinz B, etal |title=Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization |journal=EMBO J. |volume=24 |issue= 5 |pages= 875–84 |year= 2005 |pmid= 15692564 |doi= 10.1038/sj.emboj.7600565 | pmc=554119 }}
*{{cite journal | author=Turnbull AP, Kümmel D, Prinz B, ''et al.'' |title=Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization. |journal=EMBO J. |volume=24 |issue= 5 |pages= 875-84 |year= 2005 |pmid= 15692564 |doi= 10.1038/sj.emboj.7600565 }}
*{{cite journal  | vauthors=Loh E, Peter F, Subramaniam VN, Hong W |title=Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus |journal=J. Cell Sci. |volume=118 |issue= Pt 6 |pages= 1209–22 |year= 2005 |pmid= 15728249 |doi= 10.1242/jcs.01723 }}
*{{cite journal  | author=Loh E, Peter F, Subramaniam VN, Hong W |title=Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. |journal=J. Cell. Sci. |volume=118 |issue= Pt 6 |pages= 1209-22 |year= 2005 |pmid= 15728249 |doi= 10.1242/jcs.01723 }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal   |vauthors=Kim MS, Yi MJ, Lee KH, etal |title=Biochemical and crystallographic studies reveal a specific interaction between TRAPP subunits Trs33p and Bet3p |journal=Traffic |volume=6 |issue= 12 |pages= 1183–95 |year= 2006 |pmid= 16262728 |doi= 10.1111/j.1600-0854.2005.00352.x }}
*{{cite journal | author=Kim MS, Yi MJ, Lee KH, ''et al.'' |title=Biochemical and crystallographic studies reveal a specific interaction between TRAPP subunits Trs33p and Bet3p. |journal=Traffic |volume=6 |issue= 12 |pages= 1183-95 |year= 2006 |pmid= 16262728 |doi= 10.1111/j.1600-0854.2005.00352.x }}
*{{cite journal   |vauthors=Kümmel D, Müller JJ, Roske Y, etal |title=Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2 |journal=J. Mol. Biol. |volume=361 |issue= 1 |pages= 22–32 |year= 2006 |pmid= 16828797 |doi= 10.1016/j.jmb.2006.06.012 }}
*{{cite journal | author=Kümmel D, Müller JJ, Roske Y, ''et al.'' |title=Structure of the Bet3-Tpc6B core of TRAPP: two Tpc6 paralogs form trimeric complexes with Bet3 and Mum2. |journal=J. Mol. Biol. |volume=361 |issue= 1 |pages= 22-32 |year= 2006 |pmid= 16828797 |doi= 10.1016/j.jmb.2006.06.012 }}
*{{cite journal   |vauthors=Yu S, Satoh A, Pypaert M, etal |title=mBet3p is required for homotypic COPII vesicle tethering in mammalian cells |journal=J. Cell Biol. |volume=174 |issue= 3 |pages= 359–68 |year= 2006 |pmid= 16880271 |doi= 10.1083/jcb.200603044 | pmc=2064232 }}
*{{cite journal | author=Yu S, Satoh A, Pypaert M, ''et al.'' |title=mBet3p is required for homotypic COPII vesicle tethering in mammalian cells. |journal=J. Cell Biol. |volume=174 |issue= 3 |pages= 359-68 |year= 2006 |pmid= 16880271 |doi= 10.1083/jcb.200603044 }}
*{{cite journal  | vauthors=Kümmel D, Heinemann U, Veit M |title=Unique self-palmitoylation activity of the transport protein particle component Bet3: A mechanism required for protein stability |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 34 |pages= 12701–6 |year= 2006 |pmid= 16908848 |doi= 10.1073/pnas.0603513103 | pmc=1562543 }}
*{{cite journal  | author=Kümmel D, Heinemann U, Veit M |title=Unique self-palmitoylation activity of the transport protein particle component Bet3: a mechanism required for protein stability. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 34 |pages= 12701-6 |year= 2006 |pmid= 16908848 |doi= 10.1073/pnas.0603513103 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=27095}}
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Latest revision as of 21:02, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Trafficking protein particle complex subunit 3 is a protein that in humans is encoded by the TRAPPC3 gene.[1][2]


References

  1. ↑ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  2. ↑ "Entrez Gene: TRAPPC3 trafficking protein particle complex 3".

Further reading



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