NECAP2: Difference between revisions

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Latest revision as of 12:48, 5 September 2017

Adaptin ear-binding coat-associated protein 2 is a protein that in humans is encoded by the NECAP2 gene.^[1]^[2]^[3]

Interactions

NECAP2 has been shown to interact with AP1G1.^[4]

References

↑ Ritter B, Philie J, Girard M, Tung EC, Blondeau F, McPherson PS (Oct 2003). "Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif". EMBO Rep. 4 (11): 1089–95. doi:10.1038/sj.embor.embor7400004. PMC 1326374. PMID 14555962.
↑ Ritter B, Blondeau F, Denisov AY, Gehring K, McPherson PS (Oct 2004). "Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics". Biochem. Soc. Trans. 32 (Pt 5): 769–73. doi:10.1042/BST0320769. PMID 15494011.
↑ "Entrez Gene: NECAP2 NECAP endocytosis associated 2".
↑ Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS (Feb 2004). "Definition of the consensus motif recognized by gamma-adaptin ear domains". J. Biol. Chem. 279 (9): 8018–28. doi:10.1074/jbc.M311873200. PMID 14665628.

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hartley JL, Temple GF, Brasch MA (2000). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O (2000). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi:10.1093/dnares/7.6.357. PMID 11214971.
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS (2004). "Definition of the consensus motif recognized by gamma-adaptin ear domains". J. Biol. Chem. 279 (9): 8018–28. doi:10.1074/jbc.M311873200. PMID 14665628.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[pmid14555962-1] Ritter B, Philie J, Girard M, Tung EC, Blondeau F, McPherson PS (Oct 2003). "Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif". EMBO Rep. 4 (11): 1089–95. doi:10.1038/sj.embor.embor7400004. PMC 1326374. PMID 14555962.

[pmid15494011-2] Ritter B, Blondeau F, Denisov AY, Gehring K, McPherson PS (Oct 2004). "Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics". Biochem. Soc. Trans. 32 (Pt 5): 769–73. doi:10.1042/BST0320769. PMID 15494011.

[entrez-3] "Entrez Gene: NECAP2 NECAP endocytosis associated 2".

[pmid14665628-4] Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS (Feb 2004). "Definition of the consensus motif recognized by gamma-adaptin ear domains". J. Biol. Chem. 279 (9): 8018–28. doi:10.1074/jbc.M311873200. PMID 14665628.

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@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''Adaptin ear-binding coat-associated protein 2''' is a [[protein]] that in humans is encoded by the ''NECAP2'' [[gene]].<ref name="pmid14555962">{{cite journal | vauthors = Ritter B, Philie J, Girard M, Tung EC, Blondeau F, McPherson PS | title = Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif | journal = EMBO Rep. | volume = 4 | issue = 11 | pages = 1089–95  | date = Oct 2003 | pmid = 14555962 | pmc = 1326374 | doi = 10.1038/sj.embor.embor7400004 }}</ref><ref name="pmid15494011">{{cite journal | vauthors = Ritter B, Blondeau F, Denisov AY, Gehring K, McPherson PS | title = Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics | journal = Biochem. Soc. Trans. | volume = 32 | issue = Pt 5 | pages = 769–73  | date = Oct 2004 | pmid = 15494011 | pmc =  | doi = 10.1042/BST0320769 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: NECAP2 NECAP endocytosis associated 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55707| accessdate = }}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+== Interactions ==
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = NECAP endocytosis associated 2
- | HGNCid = 25528
- | Symbol = NECAP2
- | AltSymbols =; FLJ10420; RP4-798A10.1
- | OMIM =
- | ECnumber =
- | Homologene = 9168
- | MGIid = 1913397
- | GeneAtlas_image1 = PBB_GE_NECAP2_220731_s_at_tn.png
- | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
- | Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005905 |text = coated pit}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0030125 |text = clathrin vesicle coat}}
- | Process = {{GNF_GO|id=GO:0006897 |text = endocytosis}} {{GNF_GO|id=GO:0015031 |text = protein transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 55707
-    | Hs_Ensembl = ENSG00000157191
-    | Hs_RefseqProtein = NP_060560
-    | Hs_RefseqmRNA = NM_018090
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 1
-    | Hs_GenLoc_start = 16639806
-    | Hs_GenLoc_end = 16659160
-    | Hs_Uniprot = Q9NVZ3
-    | Mm_EntrezGene = 66147
-    | Mm_Ensembl = ENSMUSG00000028923
-    | Mm_RefseqmRNA = NM_025383
-    | Mm_RefseqProtein = NP_079659
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 4
-    | Mm_GenLoc_start = 140338593
-    | Mm_GenLoc_end = 140350409
-    | Mm_Uniprot = Q3TBZ6
-  }}
-}}
-'''NECAP endocytosis associated 2''', also known as '''NECAP2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: NECAP2 NECAP endocytosis associated 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55707| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
+NECAP2 has been shown to [[Protein-protein interaction|interact]] with [[AP1G1]].<ref name=pmid14665628>{{cite journal | vauthors = Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS | title = Definition of the consensus motif recognized by gamma-adaptin ear domains | journal = J. Biol. Chem. | volume = 279 | issue = 9 | pages = 8018–28  | date = Feb 2004 | pmid = 14665628 | doi = 10.1074/jbc.M311873200 }}</ref>
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
+== References ==
-{{reflist|2}}
+{{reflist}}
-==Further reading==
+== Further reading ==
 {{refbegin | 2}}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1-2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
-| citations =
+* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1-2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
-*{{cite journal  | author=Ritter B, Blondeau F, Denisov AY, ''et al.'' |title=Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics. |journal=Biochem. Soc. Trans. |volume=32 |issue= Pt 5 |pages= 769-73 |year= 2005 |pmid= 15494011 |doi= 10.1042/BST0320769 }}
+* {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Res. | volume = 10 | issue = 11 | pages = 1788–95 | year = 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+* {{cite journal | vauthors = Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O | title = Characterization of long cDNA clones from human adult spleen | journal = DNA Res. | volume = 7 | issue = 6 | pages = 357–66 | year = 2000 | pmid = 11214971 | doi = 10.1093/dnares/7.6.357 }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+* {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Rep. | volume = 1 | issue = 3 | pages = 287–92 | year = 2000 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }}
-*{{cite journal  | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=  }}
+* {{cite journal | vauthors = Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS | title = Definition of the consensus motif recognized by gamma-adaptin ear domains | journal = J. Biol. Chem. | volume = 279 | issue = 9 | pages = 8018–28 | year = 2004 | pmid = 14665628 | doi = 10.1074/jbc.M311873200 }}
-*{{cite journal  | author=Hattori A, Okumura K, Nagase T, ''et al.'' |title=Characterization of long cDNA clones from human adult spleen. |journal=DNA Res. |volume=7 |issue= 6 |pages= 357-66 |year= 2001 |pmid= 11214971 |doi=  }}
+* {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Res. | volume = 14 | issue = 10B | pages = 2136–44 | year = 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
-*{{cite journal  | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
+* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+* {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Res. | volume = 34 | issue = Database issue | pages = D415-8 | year = 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
-*{{cite journal  | author=Ritter B, Philie J, Girard M, ''et al.'' |title=Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif. |journal=EMBO Rep. |volume=4 |issue= 11 |pages= 1089-95 |year= 2004 |pmid= 14555962 |doi= 10.1038/sj.embor.embor7400004 }}
-*{{cite journal  | author=Mattera R, Ritter B, Sidhu SS, ''et al.'' |title=Definition of the consensus motif recognized by gamma-adaptin ear domains. |journal=J. Biol. Chem. |volume=279 |issue= 9 |pages= 8018-28 |year= 2004 |pmid= 14665628 |doi= 10.1074/jbc.M311873200 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
-*{{cite journal  | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
-*{{cite journal  | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
-}}
 {{refend}}
-{{protein-stub}}
+[[Category:Human proteins]]
-{{WikiDoc Sources}}
+{{gene-1-stub}}

NECAP2: Difference between revisions

Latest revision as of 12:48, 5 September 2017

Interactions

References

Further reading

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