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{{Infobox_gene}}
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'''Ras-related protein Rab-6C''' is a [[protein]] that in humans is encoded by the ''RAB6C'' [[gene]].<ref name="pmid11054569">{{cite journal |vauthors=Shan J, Mason JM, Yuan L, Barcia M, Porti D, Calabro A, Budman D, Vinciguerra V, Xu H | title = Rab6c, a new member of the rab gene family, is involved in drug resistance in MCF7/AdrR cells | journal = Gene | volume = 257 | issue = 1 | pages = 67–75 |date=Dec 2000 | pmid = 11054569 | pmc =  | doi =10.1016/S0378-1119(00)00395-4 }}</ref><ref name="pmid17426708">{{cite journal |vauthors=Tian K, Wang Y, Xu H | title = WTH3 is a direct target of the p53 protein | journal = Br J Cancer | volume = 96 | issue = 10 | pages = 1579–86 |date=May 2007 | pmid = 17426708 | pmc = 2359938 | doi = 10.1038/sj.bjc.6603724 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB6C RAB6C, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84084| accessdate = }}</ref>
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| image = PBB_Protein_RAB6C_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1yzq.
| PDB = {{PDB2|1yzq}}
| Name = RAB6C, member RAS oncogene family
| HGNCid = 16525
| Symbol = RAB6C
| AltSymbols =; WTH3
| OMIM = 
| ECnumber =
| Homologene =
| MGIid =
| GeneAtlas_image1 = PBB_GE_RAB6C_210406_s_at_tn.png
  | GeneAtlas_image2 = PBB_GE_RAB6C_201047_x_at_tn.png
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003924 |text = GTPase activity}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}}
| Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}} {{GNF_GO|id=GO:0042493 |text = response to drug}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 84084
    | Hs_Ensembl = ENSG00000185023
    | Hs_RefseqProtein = NP_115520
    | Hs_RefseqmRNA = NM_032144
    | Hs_GenLoc_db =
    | Hs_GenLoc_chr = 2
    | Hs_GenLoc_start = 130453705
    | Hs_GenLoc_end = 130456781
    | Hs_Uniprot = Q9H0N0
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
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    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
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'''RAB6C, member RAS oncogene family''', also known as '''RAB6C''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB6C RAB6C, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84084| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author= |title=Toward a complete human genome sequence. |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097-108 |year= 1999 |pmid= 9847074 |doi=  }}
*{{cite journal  |title=Toward a complete human genome sequence |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi=  10.1101/gr.8.11.1097}}
*{{cite journal | author=Fitzgerald ML, Reed GL |title=Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distribution. |journal=Biochem. J. |volume=342 ( Pt 2) |issue=  |pages= 353-60 |year= 1999 |pmid= 10455022 |doi= }}
*{{cite journal |title=Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distribution |journal=Biochem. J. |volume=342 ( Pt 2) |issue=  2|pages= 353–60 |year= 1999 |pmid= 10455022 |doi=10.1042/0264-6021:3420353 |author1=Fitzgerald ML |author2=Reed GL |name-list-format=vanc |pmc=1220472 }}
*{{cite journal  | author=Shan J, Mason JM, Yuan L, ''et al.'' |title=Rab6c, a new member of the rab gene family, is involved in drug resistance in MCF7/AdrR cells. |journal=Gene |volume=257 |issue= 1 |pages= 67-75 |year= 2001 |pmid= 11054569 |doi=  }}
*{{cite journal |title=Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R |display-authors=3 |author1=Wiemann S |author2=Weil B |author3=Wellenreuther R |name-list-format=vanc |last4=Gassenhuber |first4=J |last5=Glassl |first5=S |last6=Ansorge |first6=W |last7=Böcher |first7=M |last8=Blöcker |first8=H |last9=Bauersachs |first9=S |pmc=311072}}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
*{{cite journal |title=WTH3, a new member of the Rab6 gene family, and multidrug resistance |journal=Biochim. Biophys. Acta |volume=1589 |issue= 2 |pages= 112–23 |year= 2002 |pmid= 12007787 |doi=10.1016/S0167-4889(02)00164-7 |author1=Shan J |author2=Yuan L |author3=Budman DR |author4=Xu HP |name-list-format=vanc }}
*{{cite journal | author=Shan J, Yuan L, Budman DR, Xu HP |title=WTH3, a new member of the Rab6 gene family, and multidrug resistance. |journal=Biochim. Biophys. Acta |volume=1589 |issue= 2 |pages= 112-23 |year= 2002 |pmid= 12007787 |doi=  }}
*{{cite journal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |display-authors=3 |author1=Strausberg RL |author2=Feingold EA |author3=Grouse LH |name-list-format=vanc |last4=Derge |first4=JG |last5=Klausner |first5=RD |last6=Collins |first6=FS |last7=Wagner |first7=L |last8=Shenmen |first8=CM |last9=Schuler |first9=GD |pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=3 |author1=Ota T |author2=Suzuki Y |author3=Nishikawa T |name-list-format=vanc |last4=Otsuki |first4=T |last5=Sugiyama |first5=T |last6=Irie |first6=R |last7=Wakamatsu |first7=A |last8=Hayashi |first8=K |last9=Sato |first9=H }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |display-authors=3 |author1=Gerhard DS |author2=Wagner L |author3=Feingold EA |name-list-format=vanc |last4=Shenmen |first4=CM |last5=Grouse |first5=LH |last6=Schuler |first6=G |last7=Klein |first7=SL |last8=Old |first8=S |last9=Rasooly |first9=R |pmc=528928 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal |title=Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells |journal=Cancer Res. |volume=65 |issue= 21 |pages= 10024–31 |year= 2005 |pmid= 16267028 |doi= 10.1158/0008-5472.CAN-05-1944 |display-authors=3 |author1=Tian K |author2=Jurukovski V |author3=Wang XP |name-list-format=vanc |last4=Kaplan |first4=MH |last5=Xu |first5=H }}
*{{cite journal | author=Tian K, Jurukovski V, Wang XP, ''et al.'' |title=Epigenetic regulation of WTH3 in primary and cultured drug-resistant breast cancer cells. |journal=Cancer Res. |volume=65 |issue= 21 |pages= 10024-31 |year= 2005 |pmid= 16267028 |doi= 10.1158/0008-5472.CAN-05-1944 }}
*{{cite journal  | author=Tian K, Wang Y, Xu H |title=WTH3 is a direct target of the p53 protein. |journal=Br. J. Cancer |volume=96 |issue= 10 |pages= 1579-86 |year= 2007 |pmid= 17426708 |doi= 10.1038/sj.bjc.6603724 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=84084}}
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Latest revision as of 08:47, 10 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ras-related protein Rab-6C is a protein that in humans is encoded by the RAB6C gene.[1][2][3]


References

  1. ↑ Shan J, Mason JM, Yuan L, Barcia M, Porti D, Calabro A, Budman D, Vinciguerra V, Xu H (Dec 2000). "Rab6c, a new member of the rab gene family, is involved in drug resistance in MCF7/AdrR cells". Gene. 257 (1): 67–75. doi:10.1016/S0378-1119(00)00395-4. PMID 11054569.
  2. ↑ Tian K, Wang Y, Xu H (May 2007). "WTH3 is a direct target of the p53 protein". Br J Cancer. 96 (10): 1579–86. doi:10.1038/sj.bjc.6603724. PMC 2359938. PMID 17426708.
  3. ↑ "Entrez Gene: RAB6C RAB6C, member RAS oncogene family".

Further reading



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