TFDP2: Difference between revisions

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{{Underlinked|date=June 2016}}
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{{Infobox_gene}}
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'''Transcription factor Dp-2''' is a [[protein]] that in humans is encoded by the ''TFDP2'' [[gene]].<ref name="pmid7784053">{{cite journal | vauthors = Zhang Y, Chellappan SP | title = Cloning and characterization of human DP2, a novel dimerization partner of E2F | journal = Oncogene | volume = 10 | issue = 11 | pages = 2085–93 |date=Jul 1995 | pmid = 7784053 | pmc =  | doi = }}</ref><ref name="pmid9027491">{{cite journal | vauthors = Zhang Y, Venkatraj VS, Fischer SG, Warburton D, Chellappan SP | title = Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family | journal = Genomics | volume = 39 | issue = 1 | pages = 95–8 |date=Mar 1997 | pmid = 9027491 | pmc =  | doi = 10.1006/geno.1996.4473 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7029| accessdate = }}</ref>
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{{GNF_Protein_box
| image = PBB_Protein_TFDP2_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1cf7.
| PDB = {{PDB2|1cf7}}
| Name = Transcription factor Dp-2 (E2F dimerization partner 2)
| HGNCid = 11751
| Symbol = TFDP2
| AltSymbols =; DP2; Dp-2
| OMIM = 602160
| ECnumber = 
| Homologene = 4578
| MGIid = 107167
| GeneAtlas_image1 = PBB_GE_TFDP2_203588_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_TFDP2_203589_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0003712 |text = transcription cofactor activity}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005667 |text = transcription factor complex}}
  | Process = {{GNF_GO|id=GO:0000074 |text = regulation of progression through cell cycle}} {{GNF_GO|id=GO:0006259 |text = DNA metabolic process}} {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006357 |text = regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0007049 |text = cell cycle}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 7029
    | Hs_Ensembl = ENSG00000114126
    | Hs_RefseqProtein = NP_006277
    | Hs_RefseqmRNA = NM_006286
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 3
    | Hs_GenLoc_start = 143153034
    | Hs_GenLoc_end = 143351008
    | Hs_Uniprot = Q14188
    | Mm_EntrezGene = 211586
    | Mm_Ensembl = ENSMUSG00000032411
    | Mm_RefseqmRNA = XM_975033
    | Mm_RefseqProtein = XP_980127
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 9
    | Mm_GenLoc_start = 96005656
    | Mm_GenLoc_end = 96128193
    | Mm_Uniprot = Q3TR88
  }}
}}
'''Transcription factor Dp-2 (E2F dimerization partner 2)''', also known as '''TFDP2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7029| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Wu CL, Zukerberg LR, Ngwu C, ''et al.'' |title=In vivo association of E2F and DP family proteins. |journal=Mol. Cell. Biol. |volume=15 |issue= 5 |pages= 2536-46 |year= 1995 |pmid= 7739537 |doi=  }}
*{{cite journal   |vauthors=Wu CL, Zukerberg LR, Ngwu C, etal |title=In vivo association of E2F and DP family proteins |journal=Mol. Cell. Biol. |volume=15 |issue= 5 |pages= 2536–46 |year= 1995 |pmid= 7739537 |doi=  10.1128/mcb.15.5.2536| pmc=230484 }}
*{{cite journal  | author=Zhang Y, Chellappan SP |title=Cloning and characterization of human DP2, a novel dimerization partner of E2F. |journal=Oncogene |volume=10 |issue= 11 |pages= 2085-93 |year= 1995 |pmid= 7784053 |doi=  }}
*{{cite journal   |vauthors=Rogers KT, Higgins PD, Milla MM, etal |title=DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 15 |pages= 7594–9 |year= 1996 |pmid= 8755520 |doi=10.1073/pnas.93.15.7594  | pmc=38791  }}
*{{cite journal | author=Rogers KT, Higgins PD, Milla MM, ''et al.'' |title=DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 15 |pages= 7594-9 |year= 1996 |pmid= 8755520 |doi=  }}
*{{cite journal  | vauthors=Loiseau L, Pasteau S, Brun G |title=Molecular cloning and expression pattern of the DP members of the chicken E2F transcription factor |journal=Gene Expr. |volume=6 |issue= 5 |pages= 259–73 |year= 1998 |pmid= 9368098 |doi=  }}
*{{cite journal  | author=Zhang Y, Venkatraj VS, Fischer SG, ''et al.'' |title=Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family. |journal=Genomics |volume=39 |issue= 1 |pages= 95-8 |year= 1997 |pmid= 9027491 |doi= 10.1006/geno.1996.4473 }}
*{{cite journal   |vauthors=Trimarchi JM, Fairchild B, Verona R, etal |title=E2F-6, a member of the E2F family that can behave as a transcriptional repressor |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 6 |pages= 2850–5 |year= 1998 |pmid= 9501179 |doi=10.1073/pnas.95.6.2850  | pmc=19658 }}
*{{cite journal  | author=Loiseau L, Pasteau S, Brun G |title=Molecular cloning and expression pattern of the DP members of the chicken E2F transcription factor. |journal=Gene Expr. |volume=6 |issue= 5 |pages= 259-73 |year= 1998 |pmid= 9368098 |doi=  }}
*{{cite journal  | vauthors=Gaubatz S, Wood JG, Livingston DM |title=Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6 |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 16 |pages= 9190–5 |year= 1998 |pmid= 9689056 |doi=10.1073/pnas.95.16.9190  | pmc=21314 }}
*{{cite journal | author=Trimarchi JM, Fairchild B, Verona R, ''et al.'' |title=E2F-6, a member of the E2F family that can behave as a transcriptional repressor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 6 |pages= 2850-5 |year= 1998 |pmid= 9501179 |doi=  }}
*{{cite journal  | vauthors=Zheng N, Fraenkel E, Pabo CO, Pavletich NP |title=Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F–DP |journal=Genes Dev. |volume=13 |issue= 6 |pages= 666–74 |year= 1999 |pmid= 10090723 |doi=10.1101/gad.13.6.666  | pmc=316551 }}
*{{cite journal  | author=Gaubatz S, Wood JG, Livingston DM |title=Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 16 |pages= 9190-5 |year= 1998 |pmid= 9689056 |doi=  }}
*{{cite journal   |vauthors=Korz C, Pscherer A, Benner A, etal |title=Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes |journal=Blood |volume=99 |issue= 12 |pages= 4554–61 |year= 2002 |pmid= 12036888 |doi=10.1182/blood.V99.12.4554 }}
*{{cite journal  | author=Zheng N, Fraenkel E, Pabo CO, Pavletich NP |title=Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. |journal=Genes Dev. |volume=13 |issue= 6 |pages= 666-74 |year= 1999 |pmid= 10090723 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Korz C, Pscherer A, Benner A, ''et al.'' |title=Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes. |journal=Blood |volume=99 |issue= 12 |pages= 4554-61 |year= 2002 |pmid= 12036888 |doi=  }}
*{{cite journal   |vauthors=Park KK, Deok Ahn J, Lee IK, etal |title=Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP |journal=Biochem. Biophys. Res. Commun. |volume=308 |issue= 4 |pages= 689–97 |year= 2003 |pmid= 12927774 |doi=10.1016/S0006-291X(03)01455-4 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Park KK, Deok Ahn J, Lee IK, ''et al.'' |title=Inhibitory effects of novel E2F decoy oligodeoxynucleotides on mesangial cell proliferation by coexpression of E2F/DP. |journal=Biochem. Biophys. Res. Commun. |volume=308 |issue= 4 |pages= 689-97 |year= 2003 |pmid= 12927774 |doi=  }}
*{{cite journal   |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=7029}}
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Latest revision as of 11:47, 15 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Transcription factor Dp-2 is a protein that in humans is encoded by the TFDP2 gene.[1][2][3]


References

  1. ↑ Zhang Y, Chellappan SP (Jul 1995). "Cloning and characterization of human DP2, a novel dimerization partner of E2F". Oncogene. 10 (11): 2085–93. PMID 7784053.
  2. ↑ Zhang Y, Venkatraj VS, Fischer SG, Warburton D, Chellappan SP (Mar 1997). "Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family". Genomics. 39 (1): 95–8. doi:10.1006/geno.1996.4473. PMID 9027491.
  3. ↑ "Entrez Gene: TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)".

Further reading



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