AFF1: Difference between revisions

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Latest revision as of 17:52, 29 August 2017

AF4/FMR2 family member 1 is a protein that in humans is encoded by the AFF1 gene.^[1]^[2]^[3]^[4]

DISCONTINUED: The record for PBM1 has been withdrawn by HGNC.^[4]

References

↑ Domer PH, Fakharzadeh SS, Chen CS, Jockel J, Johansen L, Silverman GA, Kersey JH, Korsmeyer SJ (Sep 1993). "Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product". Proc Natl Acad Sci U S A. 90 (16): 7884–8. doi:10.1073/pnas.90.16.7884. PMC 47247. PMID 7689231.
↑ Gu Y, Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM, Canaani E (Dec 1992). "The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene". Cell. 71 (4): 701–8. doi:10.1016/0092-8674(92)90603-A. PMID 1423625.
↑ Chen CS, Hilden JM, Frestedt J, Domer PH, Moore R, Korsmeyer SJ, Kersey JH (Sep 1993). "The chromosome 4q21 gene (AF-4/FEL) is widely expressed in normal tissues and shows breakpoint diversity in t(4;11)(q21;q23) acute leukemia". Blood. 82 (4): 1080–5. PMID 8353274.
↑ ^4.0 ^4.1 "Entrez Gene: AFF1 AF4/FMR2 family, member 1".

External links

Human AFF1 genome location and AFF1 gene details page in the UCSC Genome Browser.

Morrissey J, Tkachuk DC, Milatovich A, et al. (1993). "A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias". Blood. 81 (5): 1124–31. PMID 8443374.
Nakamura T, Alder H, Gu Y, et al. (1993). "Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs". Proc. Natl. Acad. Sci. U.S.A. 90 (10): 4631–5. doi:10.1073/pnas.90.10.4631. PMC 46566. PMID 8506309.
Frestedt JL, Hilden JM, Kersey JH (1996). "AF4/FEL, a gene involved in infant leukemia: sequence variations, gene structure, and possible homology with a genomic sequence on 5q31". DNA Cell Biol. 15 (8): 669–78. doi:10.1089/dna.1996.15.669. PMID 8769569.
Nilson I, Reichel M, Ennas MG, et al. (1997). "Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia". Br. J. Haematol. 98 (1): 157–69. doi:10.1046/j.1365-2141.1997.1522966.x. PMID 9233580.
Megonigal MD, Rappaport EF, Jones DH, et al. (1997). "Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias". Proc. Natl. Acad. Sci. U.S.A. 94 (21): 11583–8. doi:10.1073/pnas.94.21.11583. PMC 23546. PMID 9326653.
Felix CA, Kim CS, Megonigal MD, et al. (1997). "Panhandle polymerase chain reaction amplifies MLL genomic translocation breakpoint involving unknown partner gene". Blood. 90 (12): 4679–86. PMID 9389682.
Isnard P, Depetris D, Mattei MG, et al. (1999). "cDNA cloning, expression and chromosomal localization of the murine AF-4 gene involved in human leukemia". Mamm. Genome. 9 (12): 1065–8. doi:10.1007/s003359900927. PMID 9880680.
Felix CA, Hosler MR, Slater DJ, et al. (2000). "Duplicated regions of AF-4 intron 4 at t(4;11) translocation breakpoints". Mol. Diagn. 4 (4): 269–83. doi:10.1016/S1084-8592(99)80002-2. PMID 10671636.
Reichel M, Gillert E, Breitenlohner I, et al. (2001). "Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research". Leukemia. 15 (2): 286–8. doi:10.1038/sj.leu.2402018. PMID 11236948.
Raffini LJ, Slater DJ, Rappaport EF, et al. (2002). "Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6". Proc. Natl. Acad. Sci. U.S.A. 99 (7): 4568–73. doi:10.1073/pnas.062066799. PMC 123688. PMID 11930009.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bertrand FE, Spengeman JD, Shah N, LeBien TW (2004). "B-cell development in the presence of the MLL/AF4 oncoprotein proceeds in the absence of HOX A7 and HOX A9 expression". Leukemia. 17 (12): 2454–9. doi:10.1038/sj.leu.2403178. PMID 14562113.
Caslini C, Serna A, Rossi V, et al. (2004). "Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein". Leukemia. 18 (6): 1064–71. doi:10.1038/sj.leu.2403321. PMID 14990976.
Bursen A, Moritz S, Gaussmann A, et al. (2004). "Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology?". Oncogene. 23 (37): 6237–49. doi:10.1038/sj.onc.1207837. PMID 15221006.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Xia ZB, Popovic R, Chen J, et al. (2005). "The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression". Proc. Natl. Acad. Sci. U.S.A. 102 (39): 14028–33. doi:10.1073/pnas.0506464102. PMC 1236570. PMID 16169901.

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[pmid7689231-1] Domer PH, Fakharzadeh SS, Chen CS, Jockel J, Johansen L, Silverman GA, Kersey JH, Korsmeyer SJ (Sep 1993). "Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product". Proc Natl Acad Sci U S A. 90 (16): 7884–8. doi:10.1073/pnas.90.16.7884. PMC 47247. PMID 7689231.

[pmid1423625-2] Gu Y, Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM, Canaani E (Dec 1992). "The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene". Cell. 71 (4): 701–8. doi:10.1016/0092-8674(92)90603-A. PMID 1423625.

[pmid8353274-3] Chen CS, Hilden JM, Frestedt J, Domer PH, Moore R, Korsmeyer SJ, Kersey JH (Sep 1993). "The chromosome 4q21 gene (AF-4/FEL) is widely expressed in normal tissues and shows breakpoint diversity in t(4;11)(q21;q23) acute leukemia". Blood. 82 (4): 1080–5. PMID 8353274.

[entrez-4] 4.0 ^4.1 "Entrez Gene: AFF1 AF4/FMR2 family, member 1".

[1]

[2]

[3]

[4]

@@ Line 1: / Line 1: @@
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''AF4/FMR2 family member 1''' is a [[protein]] that in [[human]]s is encoded by the ''AFF1'' [[gene]].<ref name="pmid7689231">{{cite journal | vauthors = Domer PH, Fakharzadeh SS, Chen CS, Jockel J, Johansen L, Silverman GA, Kersey JH, Korsmeyer SJ | title = Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product | journal = Proc Natl Acad Sci U S A | volume = 90 | issue = 16 | pages = 7884–8 |date=Sep 1993 | pmid = 7689231 | pmc = 47247 | doi =10.1073/pnas.90.16.7884  }}</ref><ref name="pmid1423625">{{cite journal | vauthors = Gu Y, Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM, Canaani E | title = The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene | journal = Cell | volume = 71 | issue = 4 | pages = 701–8 |date=Dec 1992 | pmid = 1423625 | pmc =  | doi =10.1016/0092-8674(92)90603-A  }}</ref><ref name="pmid8353274">{{cite journal | vauthors = Chen CS, Hilden JM, Frestedt J, Domer PH, Moore R, Korsmeyer SJ, Kersey JH | title = The chromosome 4q21 gene (AF-4/FEL) is widely expressed in normal tissues and shows breakpoint diversity in t(4;11)(q21;q23) acute leukemia | journal = Blood | volume = 82 | issue = 4 | pages = 1080–5 |date=Sep 1993 | pmid = 8353274 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: AFF1 AF4/FMR2 family, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4299| accessdate = }}</ref>
-| update_page = yes
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-| update_citations = yes
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-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = AF4/FMR2 family, member 1
- | HGNCid = 7135
- | Symbol = AFF1
- | AltSymbols =; AF-4; AF4; AF4-MLL; MGC134969; MLL/AF4; MLLT2; PBM1
- | OMIM = 159557
- | ECnumber =
- | Homologene = 4340
- | MGIid = 1100819
- | Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}}
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process =
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 4299
-    | Hs_Ensembl =
-    | Hs_RefseqProtein = NP_005926
-    | Hs_RefseqmRNA = NM_005935
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr =
-    | Hs_GenLoc_start =
-    | Hs_GenLoc_end =
-    | Hs_Uniprot =
-    | Mm_EntrezGene = 17355
-    | Mm_Ensembl = ENSMUSG00000029313
-    | Mm_RefseqmRNA = NM_001080798
-    | Mm_RefseqProtein = NP_001074267
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 5
-    | Mm_GenLoc_start = 104023409
-    | Mm_GenLoc_end = 104091125
-    | Mm_Uniprot = O35233
-  }}
-}}
-'''AF4/FMR2 family, member 1''', also known as '''AFF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: AFF1 AF4/FMR2 family, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4299| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
 | section_title =
-| summary_text = DISCONTINUED: The record for PBM1 has been withdrawn by HGNC.<ref name="entrez">{{cite web | title = Entrez Gene: AFF1 AF4/FMR2 family, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4299| accessdate = }}</ref>
+| summary_text = DISCONTINUED: The record for PBM1 has been withdrawn by [[HGNC]].<ref name="entrez" />
 }}
 ==References==
-{{reflist|2}}
+{{reflist}}
+==External links==
+* {{UCSC gene info|AFF1}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Gu Y, Nakamura T, Alder H, ''et al.'' |title=The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. |journal=Cell |volume=71 |issue= 4 |pages= 701-8 |year= 1992 |pmid= 1423625 |doi=  }}
+*{{cite journal  | vauthors=Morrissey J, Tkachuk DC, Milatovich A |title=A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias. |journal=Blood |volume=81 |issue= 5 |pages= 1124–31 |year= 1993 |pmid= 8443374 |doi=  |display-authors=etal}}
-*{{cite journal  | author=Domer PH, Fakharzadeh SS, Chen CS, ''et al.'' |title=Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 16 |pages= 7884-8 |year= 1993 |pmid= 7689231 |doi=  }}
+*{{cite journal  | vauthors=Nakamura T, Alder H, Gu Y |title=Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 10 |pages= 4631–5 |year= 1993 |pmid= 8506309 |doi=10.1073/pnas.90.10.4631  | pmc=46566  |display-authors=etal}}
-*{{cite journal  | author=Chen CS, Hilden JM, Frestedt J, ''et al.'' |title=The chromosome 4q21 gene (AF-4/FEL) is widely expressed in normal tissues and shows breakpoint diversity in t(4;11)(q21;q23) acute leukemia. |journal=Blood |volume=82 |issue= 4 |pages= 1080-5 |year= 1993 |pmid= 8353274 |doi=  }}
+*{{cite journal  | vauthors=Frestedt JL, Hilden JM, Kersey JH |title=AF4/FEL, a gene involved in infant leukemia: sequence variations, gene structure, and possible homology with a genomic sequence on 5q31. |journal=DNA Cell Biol. |volume=15 |issue= 8 |pages= 669–78 |year= 1996 |pmid= 8769569 |doi=10.1089/dna.1996.15.669  }}
-*{{cite journal  | author=Morrissey J, Tkachuk DC, Milatovich A, ''et al.'' |title=A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias. |journal=Blood |volume=81 |issue= 5 |pages= 1124-31 |year= 1993 |pmid= 8443374 |doi=  }}
+*{{cite journal  | vauthors=Nilson I, Reichel M, Ennas MG |title=Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia. |journal=Br. J. Haematol. |volume=98 |issue= 1 |pages= 157–69 |year= 1997 |pmid= 9233580 |doi=10.1046/j.1365-2141.1997.1522966.x  |display-authors=etal}}
-*{{cite journal  | author=Nakamura T, Alder H, Gu Y, ''et al.'' |title=Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 10 |pages= 4631-5 |year= 1993 |pmid= 8506309 |doi=  }}
+*{{cite journal  | vauthors=Megonigal MD, Rappaport EF, Jones DH |title=Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 21 |pages= 11583–8 |year= 1997 |pmid= 9326653 |doi=10.1073/pnas.94.21.11583  | pmc=23546  |display-authors=etal}}
-*{{cite journal  | author=Frestedt JL, Hilden JM, Kersey JH |title=AF4/FEL, a gene involved in infant leukemia: sequence variations, gene structure, and possible homology with a genomic sequence on 5q31. |journal=DNA Cell Biol. |volume=15 |issue= 8 |pages= 669-78 |year= 1996 |pmid= 8769569 |doi=  }}
+*{{cite journal  | vauthors=Felix CA, Kim CS, Megonigal MD |title=Panhandle polymerase chain reaction amplifies MLL genomic translocation breakpoint involving unknown partner gene. |journal=Blood |volume=90 |issue= 12 |pages= 4679–86 |year= 1997 |pmid= 9389682 |doi=  |display-authors=etal}}
-*{{cite journal  | author=Nilson I, Reichel M, Ennas MG, ''et al.'' |title=Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia. |journal=Br. J. Haematol. |volume=98 |issue= 1 |pages= 157-69 |year= 1997 |pmid= 9233580 |doi=  }}
+*{{cite journal  | vauthors=Isnard P, Depetris D, Mattei MG |title=cDNA cloning, expression and chromosomal localization of the murine AF-4 gene involved in human leukemia. |journal=Mamm. Genome |volume=9 |issue= 12 |pages= 1065–8 |year= 1999 |pmid= 9880680 |doi=10.1007/s003359900927  |display-authors=etal}}
-*{{cite journal  | author=Megonigal MD, Rappaport EF, Jones DH, ''et al.'' |title=Panhandle PCR strategy to amplify MLL genomic breakpoints in treatment-related leukemias. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 21 |pages= 11583-8 |year= 1997 |pmid= 9326653 |doi=  }}
+*{{cite journal  | vauthors=Felix CA, Hosler MR, Slater DJ |title=Duplicated regions of AF-4 intron 4 at t(4;11) translocation breakpoints. |journal=Mol. Diagn. |volume=4 |issue= 4 |pages= 269–83 |year= 2000 |pmid= 10671636 |doi= 10.1016/S1084-8592(99)80002-2|display-authors=etal}}
-*{{cite journal  | author=Felix CA, Kim CS, Megonigal MD, ''et al.'' |title=Panhandle polymerase chain reaction amplifies MLL genomic translocation breakpoint involving unknown partner gene. |journal=Blood |volume=90 |issue= 12 |pages= 4679-86 |year= 1997 |pmid= 9389682 |doi=  }}
+*{{cite journal  | vauthors=Reichel M, Gillert E, Breitenlohner I |title=Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research. |journal=Leukemia |volume=15 |issue= 2 |pages= 286–8 |year= 2001 |pmid= 11236948 |doi=10.1038/sj.leu.2402018  |display-authors=etal}}
-*{{cite journal  | author=Isnard P, Depetris D, Mattei MG, ''et al.'' |title=cDNA cloning, expression and chromosomal localization of the murine AF-4 gene involved in human leukemia. |journal=Mamm. Genome |volume=9 |issue= 12 |pages= 1065-8 |year= 1999 |pmid= 9880680 |doi=  }}
+*{{cite journal  | vauthors=Raffini LJ, Slater DJ, Rappaport EF |title=Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4568–73 |year= 2002 |pmid= 11930009 |doi= 10.1073/pnas.062066799  | pmc=123688 |display-authors=etal}}
-*{{cite journal  | author=Felix CA, Hosler MR, Slater DJ, ''et al.'' |title=Duplicated regions of AF-4 intron 4 at t(4;11) translocation breakpoints. |journal=Mol. Diagn. |volume=4 |issue= 4 |pages= 269-83 |year= 2000 |pmid= 10671636 |doi= 10.154/MODI00400269 }}
+*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
-*{{cite journal  | author=Reichel M, Gillert E, Breitenlohner I, ''et al.'' |title=Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research. |journal=Leukemia |volume=15 |issue= 2 |pages= 286-8 |year= 2001 |pmid= 11236948 |doi=  }}
+*{{cite journal  | vauthors=Bertrand FE, Spengeman JD, Shah N, LeBien TW |title=B-cell development in the presence of the MLL/AF4 oncoprotein proceeds in the absence of HOX A7 and HOX A9 expression. |journal=Leukemia |volume=17 |issue= 12 |pages= 2454–9 |year= 2004 |pmid= 14562113 |doi= 10.1038/sj.leu.2403178 }}
-*{{cite journal  | author=Raffini LJ, Slater DJ, Rappaport EF, ''et al.'' |title=Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4568-73 |year= 2002 |pmid= 11930009 |doi= 10.1073/pnas.062066799 }}
+*{{cite journal  | vauthors=Caslini C, Serna A, Rossi V |title=Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein. |journal=Leukemia |volume=18 |issue= 6 |pages= 1064–71 |year= 2004 |pmid= 14990976 |doi= 10.1038/sj.leu.2403321 |display-authors=etal}}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | vauthors=Bursen A, Moritz S, Gaussmann A |title=Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology? |journal=Oncogene |volume=23 |issue= 37 |pages= 6237–49 |year= 2004 |pmid= 15221006 |doi= 10.1038/sj.onc.1207837 |display-authors=etal}}
-*{{cite journal  | author=Bertrand FE, Spengeman JD, Shah N, LeBien TW |title=B-cell development in the presence of the MLL/AF4 oncoprotein proceeds in the absence of HOX A7 and HOX A9 expression. |journal=Leukemia |volume=17 |issue= 12 |pages= 2454-9 |year= 2004 |pmid= 14562113 |doi= 10.1038/sj.leu.2403178 }}
+*{{cite journal  | vauthors=Colland F, Jacq X, Trouplin V |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104  | pmc=442148 |display-authors=etal}}
-*{{cite journal  | author=Caslini C, Serna A, Rossi V, ''et al.'' |title=Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein. |journal=Leukemia |volume=18 |issue= 6 |pages= 1064-71 |year= 2004 |pmid= 14990976 |doi= 10.1038/sj.leu.2403321 }}
+*{{cite journal  | vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101  | pmc=514446 |display-authors=etal}}
-*{{cite journal  | author=Bursen A, Moritz S, Gaussmann A, ''et al.'' |title=Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology? |journal=Oncogene |volume=23 |issue= 37 |pages= 6237-49 |year= 2004 |pmid= 15221006 |doi= 10.1038/sj.onc.1207837 }}
+*{{cite journal  | vauthors=Xia ZB, Popovic R, Chen J |title=The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 39 |pages= 14028–33 |year= 2005 |pmid= 16169901 |doi= 10.1073/pnas.0506464102  | pmc=1236570 |display-authors=etal}}
-*{{cite journal  | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
-*{{cite journal  | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
-*{{cite journal  | author=Xia ZB, Popovic R, Chen J, ''et al.'' |title=The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 39 |pages= 14028-33 |year= 2005 |pmid= 16169901 |doi= 10.1073/pnas.0506464102 }}
 }}
 {{refend}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
 {{protein-stub}}
-{{WikiDoc Sources}}

AFF1: Difference between revisions

Latest revision as of 17:52, 29 August 2017

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