HTN1: Difference between revisions

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Latest revision as of 14:10, 31 August 2017

Histatin-1 is a protein that in humans is encoded by the HTN1 gene.^[1]

References

↑ "Entrez Gene: HTN1 histatin 1".

Sugiyama K, Ogino T, Ogata K (1990). "Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva". Arch. Oral Biol. 35 (6): 415–9. doi:10.1016/0003-9969(90)90202-L. PMID 2372245.
Sabatini LM, Azen EA (1989). "Histatins, a family of salivary histidine-rich proteins, are encoded by at least two loci (HIS1 and HIS2)". Biochem. Biophys. Res. Commun. 160 (2): 495–502. doi:10.1016/0006-291X(89)92460-1. PMID 2719677.
vanderSpek JC, Wyandt HE, Skare JC, et al. (1989). "Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs". Am. J. Hum. Genet. 45 (3): 381–7. PMC 1683406. PMID 2773933.
Oppenheim FG, Xu T, McMillian FM, et al. (1988). "Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans". J. Biol. Chem. 263 (16): 7472–7. PMID 3286634.
Oppenheim FG, Yang YC, Diamond RD, et al. (1986). "The primary structure and functional characterization of the neutral histidine-rich polypeptide from human parotid secretion". J. Biol. Chem. 261 (3): 1177–82. PMID 3944083.
Sabatini LM, Ota T, Azen EA (1993). "Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family". Mol. Biol. Evol. 10 (3): 497–511. PMID 8336540.
Driscoll J, Zuo Y, Xu T, et al. (1996). "Functional comparison of native and recombinant human salivary histatin 1". J. Dent. Res. 74 (12): 1837–44. doi:10.1177/00220345950740120601. PMID 8600179.
Iontcheva I, Oppenheim FG, Offner GD, Troxler RF (2000). "Molecular mapping of statherin- and histatin-binding domains in human salivary mucin MG1 (MUC5B) by the yeast two-hybrid system". J. Dent. Res. 79 (2): 732–9. doi:10.1177/00220345000790020601. PMID 10728974.
Flora B, Gusman H, Helmerhorst EJ, et al. (2002). "A new method for the isolation of histatins 1, 3, and 5 from parotid secretion using zinc precipitation". Protein Expr. Purif. 23 (1): 198–206. doi:10.1006/prep.2001.1493. PMID 11570863.
Tamaki N, Tada T, Morita M, Watanabe T (2003). "Comparison of inhibitory activity on calcium phosphate precipitation by acidic proline-rich proteins, statherin, and histatin-1". Calcif. Tissue Int. 71 (1): 59–62. doi:10.1007/s00223-001-1084-0. PMID 12060866.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yin A, Margolis HC, Grogan J, et al. (2003). "Physical parameters of hydroxyapatite adsorption and effect on candidacidal activity of histatins". Arch. Oral Biol. 48 (5): 361–8. doi:10.1016/S0003-9969(03)00012-8. PMID 12711380.
Michels AA, Nguyen VT, Fraldi A, et al. (2003). "MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner". Mol. Cell. Biol. 23 (14): 4859–69. doi:10.1128/MCB.23.14.4859-4869.2003. PMC 162212. PMID 12832472.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Bruno LS, Li X, Wang L, et al. (2005). "Two-hybrid analysis of human salivary mucin MUC7 interactions". Biochim. Biophys. Acta. 1746 (1): 65–72. doi:10.1016/j.bbamcr.2005.08.007. PMID 16203048.
Cabras T, Fanali C, Monteiro JA, et al. (2007). "Tyrosine polysulfation of human salivary histatin 1. A post-translational modification specific of the submandibular gland". J. Proteome Res. 6 (7): 2472–80. doi:10.1021/pr0700706. PMID 17503797.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: HTN1 histatin 1".

[1]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{PBB_Controls
+'''Histatin-1''' is a [[protein]] that in humans is encoded by the ''HTN1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HTN1 histatin 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3346| accessdate = }}</ref>
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-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Histatin 1
- | HGNCid = 5283
- | Symbol = HTN1
- | AltSymbols =; HIS1
- | OMIM = 142701
- | ECnumber =
- | Homologene = 88658
- | MGIid =
- | GeneAtlas_image1 = PBB_GE_HTN1_206639_x_at_tn.png
- | Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
- | Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}}
- | Process = {{GNF_GO|id=GO:0001503 |text = ossification}} {{GNF_GO|id=GO:0006805 |text = xenobiotic metabolic process}} {{GNF_GO|id=GO:0042742 |text = defense response to bacterium}} {{GNF_GO|id=GO:0050832 |text = defense response to fungus}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 3346
-    | Hs_Ensembl = ENSG00000126550
-    | Hs_RefseqProtein = NP_002150
-    | Hs_RefseqmRNA = NM_002159
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 4
-    | Hs_GenLoc_start = 70950748
-    | Hs_GenLoc_end = 70959145
-    | Hs_Uniprot = P15515
-    | Mm_EntrezGene =
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA =
-    | Mm_RefseqProtein =
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''Histatin 1''', also known as '''HTN1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: HTN1 histatin 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3346| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
@@ Line 55: / Line 9: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Sugiyama K, Ogino T, Ogata K |title=Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva. |journal=Arch. Oral Biol. |volume=35 |issue= 6 |pages= 415-9 |year= 1990 |pmid= 2372245 |doi=  }}
+*{{cite journal  |vauthors=Sugiyama K, Ogino T, Ogata K |title=Rapid purification and characterization of histatins (histidine-rich polypeptides) from human whole saliva. |journal=Arch. Oral Biol. |volume=35 |issue= 6 |pages= 415–9 |year= 1990 |pmid= 2372245 |doi=10.1016/0003-9969(90)90202-L  }}
-*{{cite journal  | author=Sabatini LM, Azen EA |title=Histatins, a family of salivary histidine-rich proteins, are encoded by at least two loci (HIS1 and HIS2). |journal=Biochem. Biophys. Res. Commun. |volume=160 |issue= 2 |pages= 495-502 |year= 1989 |pmid= 2719677 |doi=  }}
+*{{cite journal  |vauthors=Sabatini LM, Azen EA |title=Histatins, a family of salivary histidine-rich proteins, are encoded by at least two loci (HIS1 and HIS2). |journal=Biochem. Biophys. Res. Commun. |volume=160 |issue= 2 |pages= 495–502 |year= 1989 |pmid= 2719677 |doi=10.1016/0006-291X(89)92460-1  }}
-*{{cite journal  | author=vanderSpek JC, Wyandt HE, Skare JC, ''et al.'' |title=Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs. |journal=Am. J. Hum. Genet. |volume=45 |issue= 3 |pages= 381-7 |year= 1989 |pmid= 2773933 |doi=  }}
+*{{cite journal   |vauthors=vanderSpek JC, Wyandt HE, Skare JC, etal |title=Localization of the genes for histatins to human chromosome 4q13 and tissue distribution of the mRNAs. |journal=Am. J. Hum. Genet. |volume=45 |issue= 3 |pages= 381–7 |year= 1989 |pmid= 2773933 |doi=  | pmc=1683406  }}
-*{{cite journal  | author=Oppenheim FG, Xu T, McMillian FM, ''et al.'' |title=Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans. |journal=J. Biol. Chem. |volume=263 |issue= 16 |pages= 7472-7 |year= 1988 |pmid= 3286634 |doi=  }}
+*{{cite journal   |vauthors=Oppenheim FG, Xu T, McMillian FM, etal |title=Histatins, a novel family of histidine-rich proteins in human parotid secretion. Isolation, characterization, primary structure, and fungistatic effects on Candida albicans. |journal=J. Biol. Chem. |volume=263 |issue= 16 |pages= 7472–7 |year= 1988 |pmid= 3286634 |doi=  }}
-*{{cite journal  | author=Oppenheim FG, Yang YC, Diamond RD, ''et al.'' |title=The primary structure and functional characterization of the neutral histidine-rich polypeptide from human parotid secretion. |journal=J. Biol. Chem. |volume=261 |issue= 3 |pages= 1177-82 |year= 1986 |pmid= 3944083 |doi=  }}
+*{{cite journal   |vauthors=Oppenheim FG, Yang YC, Diamond RD, etal |title=The primary structure and functional characterization of the neutral histidine-rich polypeptide from human parotid secretion. |journal=J. Biol. Chem. |volume=261 |issue= 3 |pages= 1177–82 |year= 1986 |pmid= 3944083 |doi=  }}
-*{{cite journal  | author=Sabatini LM, Ota T, Azen EA |title=Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family. |journal=Mol. Biol. Evol. |volume=10 |issue= 3 |pages= 497-511 |year= 1993 |pmid= 8336540 |doi=  }}
+*{{cite journal  |vauthors=Sabatini LM, Ota T, Azen EA |title=Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family. |journal=Mol. Biol. Evol. |volume=10 |issue= 3 |pages= 497–511 |year= 1993 |pmid= 8336540 |doi=  }}
-*{{cite journal  | author=Driscoll J, Zuo Y, Xu T, ''et al.'' |title=Functional comparison of native and recombinant human salivary histatin 1. |journal=J. Dent. Res. |volume=74 |issue= 12 |pages= 1837-44 |year= 1996 |pmid= 8600179 |doi=  }}
+*{{cite journal   |vauthors=Driscoll J, Zuo Y, Xu T, etal |title=Functional comparison of native and recombinant human salivary histatin 1. |journal=J. Dent. Res. |volume=74 |issue= 12 |pages= 1837–44 |year= 1996 |pmid= 8600179 |doi=  10.1177/00220345950740120601}}
-*{{cite journal  | author=Iontcheva I, Oppenheim FG, Offner GD, Troxler RF |title=Molecular mapping of statherin- and histatin-binding domains in human salivary mucin MG1 (MUC5B) by the yeast two-hybrid system. |journal=J. Dent. Res. |volume=79 |issue= 2 |pages= 732-9 |year= 2000 |pmid= 10728974 |doi=  }}
+*{{cite journal  |vauthors=Iontcheva I, Oppenheim FG, Offner GD, Troxler RF |title=Molecular mapping of statherin- and histatin-binding domains in human salivary mucin MG1 (MUC5B) by the yeast two-hybrid system. |journal=J. Dent. Res. |volume=79 |issue= 2 |pages= 732–9 |year= 2000 |pmid= 10728974 |doi=10.1177/00220345000790020601  }}
-*{{cite journal  | author=Flora B, Gusman H, Helmerhorst EJ, ''et al.'' |title=A new method for the isolation of histatins 1, 3, and 5 from parotid secretion using zinc precipitation. |journal=Protein Expr. Purif. |volume=23 |issue= 1 |pages= 198-206 |year= 2002 |pmid= 11570863 |doi= 10.1006/prep.2001.1493 }}
+*{{cite journal   |vauthors=Flora B, Gusman H, Helmerhorst EJ, etal |title=A new method for the isolation of histatins 1, 3, and 5 from parotid secretion using zinc precipitation. |journal=Protein Expr. Purif. |volume=23 |issue= 1 |pages= 198–206 |year= 2002 |pmid= 11570863 |doi= 10.1006/prep.2001.1493 }}
-*{{cite journal  | author=Tamaki N, Tada T, Morita M, Watanabe T |title=Comparison of inhibitory activity on calcium phosphate precipitation by acidic proline-rich proteins, statherin, and histatin-1. |journal=Calcif. Tissue Int. |volume=71 |issue= 1 |pages= 59-62 |year= 2003 |pmid= 12060866 |doi= 10.1007/s00223-001-1084-0 }}
+*{{cite journal  |vauthors=Tamaki N, Tada T, Morita M, Watanabe T |title=Comparison of inhibitory activity on calcium phosphate precipitation by acidic proline-rich proteins, statherin, and histatin-1. |journal=Calcif. Tissue Int. |volume=71 |issue= 1 |pages= 59–62 |year= 2003 |pmid= 12060866 |doi= 10.1007/s00223-001-1084-0 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Yin A, Margolis HC, Grogan J, ''et al.'' |title=Physical parameters of hydroxyapatite adsorption and effect on candidacidal activity of histatins. |journal=Arch. Oral Biol. |volume=48 |issue= 5 |pages= 361-8 |year= 2003 |pmid= 12711380 |doi=  }}
+*{{cite journal   |vauthors=Yin A, Margolis HC, Grogan J, etal |title=Physical parameters of hydroxyapatite adsorption and effect on candidacidal activity of histatins. |journal=Arch. Oral Biol. |volume=48 |issue= 5 |pages= 361–8 |year= 2003 |pmid= 12711380 |doi=10.1016/S0003-9969(03)00012-8  }}
-*{{cite journal  | author=Michels AA, Nguyen VT, Fraldi A, ''et al.'' |title=MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner. |journal=Mol. Cell. Biol. |volume=23 |issue= 14 |pages= 4859-69 |year= 2003 |pmid= 12832472 |doi=  }}
+*{{cite journal   |vauthors=Michels AA, Nguyen VT, Fraldi A, etal |title=MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner. |journal=Mol. Cell. Biol. |volume=23 |issue= 14 |pages= 4859–69 |year= 2003 |pmid= 12832472 |doi=10.1128/MCB.23.14.4859-4869.2003  | pmc=162212  }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Bruno LS, Li X, Wang L, ''et al.'' |title=Two-hybrid analysis of human salivary mucin MUC7 interactions. |journal=Biochim. Biophys. Acta |volume=1746 |issue= 1 |pages= 65-72 |year= 2005 |pmid= 16203048 |doi= 10.1016/j.bbamcr.2005.08.007 }}
+*{{cite journal   |vauthors=Bruno LS, Li X, Wang L, etal |title=Two-hybrid analysis of human salivary mucin MUC7 interactions. |journal=Biochim. Biophys. Acta |volume=1746 |issue= 1 |pages= 65–72 |year= 2005 |pmid= 16203048 |doi= 10.1016/j.bbamcr.2005.08.007 }}
-*{{cite journal  | author=Cabras T, Fanali C, Monteiro JA, ''et al.'' |title=Tyrosine polysulfation of human salivary histatin 1. A post-translational modification specific of the submandibular gland. |journal=J. Proteome Res. |volume=6 |issue= 7 |pages= 2472-80 |year= 2007 |pmid= 17503797 |doi= 10.1021/pr0700706 }}
+*{{cite journal   |vauthors=Cabras T, Fanali C, Monteiro JA, etal |title=Tyrosine polysulfation of human salivary histatin 1. A post-translational modification specific of the submandibular gland. |journal=J. Proteome Res. |volume=6 |issue= 7 |pages= 2472–80 |year= 2007 |pmid= 17503797 |doi= 10.1021/pr0700706 }}
 }}
 {{refend}}
-{{protein-stub}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
-{{WikiDoc Sources}}
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+{{Pore-forming toxins}}
+{{gene-4-stub}}

v t e Pore-forming toxins (TC 1C)
Antimicrobial cationic peptides	Cathelicidin Defensin Dermcidin Histatin (HTN1, HTN3)
Other, human	Perforin
Other, nonhuman	Cecropin Diphtheria toxin Dermaseptin Magainin Melittin Nisin Pneumolysin

HTN1: Difference between revisions

Latest revision as of 14:10, 31 August 2017

References

Further reading

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