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{{ | '''Glycophorin-E''' is a [[protein]] that in humans is encoded by the ''GYPE'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: GYPE glycophorin E| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2996| accessdate = }}</ref> | ||
}} | |||
'''Glycophorin E''' | |||
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| summary_text = The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.<ref name="entrez" | | summary_text = The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.<ref name="entrez" /> | ||
}} | }} | ||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | | *{{cite journal |vauthors=Cartron JP, Rahuel C |title=Human erythrocyte glycophorins: protein and gene structure analyses |journal=Transfusion medicine reviews |volume=6 |issue= 2 |pages= 63–92 |year= 1992 |pmid= 1591491 |doi=10.1016/S0887-7963(92)70158-8 }} | ||
*{{cite journal | author=Huang CH | *{{cite journal | author=Huang CH |title=Molecular analysis of human glycophorin MiIX gene shows a silent segment transfer and untemplated mutation resulting from gene conversion via sequence repeats |journal=Blood |volume=80 |issue= 9 |pages= 2379–87 |year= 1992 |pmid= 1421409 |doi= |name-list-format=vanc| author2=Skov F | author3=Daniels G | display-authors=3 | last4=Tippett | first4=P | last5=Blumenfeld | first5=OO }} | ||
*{{cite journal | | *{{cite journal |vauthors=Vignal A, London J, Rahuel C, Cartron JP |title=Promoter sequence and chromosomal organization of the genes encoding glycophorins A, B and E |journal=Gene |volume=95 |issue= 2 |pages= 289–293 |year= 1991 |pmid= 2249783 |doi=10.1016/0378-1119(90)90374-Z }} | ||
*{{cite journal | | *{{cite journal |vauthors=Kudo S, Fukuda M |title=Identification of a novel human glycophorin, glycophorin E, by isolation of genomic clones and complementary DNA clones utilizing polymerase chain reaction |journal=J. Biol. Chem. |volume=265 |issue= 2 |pages= 1102–10 |year= 1990 |pmid= 2295603 |doi= }} | ||
*{{cite journal | author=Vignal A | *{{cite journal | author=Vignal A |title=A novel gene member of the human glycophorin A and B gene family. Molecular cloning and expression |journal=Eur. J. Biochem. |volume=191 |issue= 3 |pages= 619–625 |year= 1990 |pmid= 2390989 |doi=10.1111/j.1432-1033.1990.tb19166.x |name-list-format=vanc| author2=Rahuel C | author3=London J | display-authors=3 | last4=Cherif Zahar | first4=Baya | last5=Schaff | first5=Sophie | last6=Hattab | first6=Claude | last7=Okubo | first7=Yasuko | last8=Cartron | first8=Jean-Pierre }} | ||
*{{cite journal | | *{{cite journal |vauthors=Kudo S, Fukuda M |title=Contribution of gene conversion to the retention of the sequence for M blood group type determinant in glycophorin E gene |journal=J. Biol. Chem. |volume=269 |issue= 37 |pages= 22969–74 |year= 1994 |pmid= 7521873 |doi= }} | ||
*{{cite journal | | *{{cite journal |vauthors=Onda M, Fukuda M |title=Detailed physical mapping of the genes encoding glycophorins A, B and E, as revealed by P1 plasmids containing human genomic DNA |journal=Gene |volume=159 |issue= 2 |pages= 225–230 |year= 1995 |pmid= 7622054 |doi=10.1016/0378-1119(95)00075-H }} | ||
*{{cite journal | | *{{cite journal |vauthors=Kudo S, Onda M, Fukuda M |title=Characterization of glycophorin A transcripts: control by the common erythroid-specific promoter and alternative usage of different polyadenylation signals |journal=J. Biochem. |volume=116 |issue= 1 |pages= 183–92 |year= 1995 |pmid= 7798177 |doi= }} | ||
*{{cite journal | | *{{cite journal |vauthors=Huang CH, Chen Y, Blumenfeld OO |title=A novel St(a) glycophorin produced via gene conversion of pseudoexon III from glycophorin E to glycophorin A gene |journal=Hum. Mutat. |volume=15 |issue= 6 |pages= 533–540 |year= 2000 |pmid= 10862083 |doi= 10.1002/1098-1004(200006)15:6<533::AID-HUMU5>3.0.CO;2-R }} | ||
*{{cite journal | author=Strausberg RL | *{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | ||
*{{cite journal | | *{{cite journal |vauthors=Wang HY, Tang H, Shen CK, Wu CI |title=Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria parasites |journal=Mol. Biol. Evol. |volume=20 |issue= 11 |pages= 1795–1804 |year= 2004 |pmid= 12949139 |doi= 10.1093/molbev/msg185 }} | ||
*{{cite journal | author=Gerhard DS | *{{cite journal | author=Gerhard DS |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–2127 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }} | ||
}} | }} | ||
{{refend}} | {{refend}} | ||
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{{gene-4-stub}} |
Latest revision as of 09:11, 31 August 2017
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External IDs | GeneCards: [1] | ||||||
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Species | Human | Mouse | |||||
Entrez |
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Ensembl |
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UniProt |
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RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
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Glycophorin-E is a protein that in humans is encoded by the GYPE gene.[1]
The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.[1]
References
Further reading
- Cartron JP, Rahuel C (1992). "Human erythrocyte glycophorins: protein and gene structure analyses". Transfusion medicine reviews. 6 (2): 63–92. doi:10.1016/S0887-7963(92)70158-8. PMID 1591491.
- Huang CH, Skov F, Daniels G, et al. (1992). "Molecular analysis of human glycophorin MiIX gene shows a silent segment transfer and untemplated mutation resulting from gene conversion via sequence repeats". Blood. 80 (9): 2379–87. PMID 1421409.
- Vignal A, London J, Rahuel C, Cartron JP (1991). "Promoter sequence and chromosomal organization of the genes encoding glycophorins A, B and E". Gene. 95 (2): 289–293. doi:10.1016/0378-1119(90)90374-Z. PMID 2249783.
- Kudo S, Fukuda M (1990). "Identification of a novel human glycophorin, glycophorin E, by isolation of genomic clones and complementary DNA clones utilizing polymerase chain reaction". J. Biol. Chem. 265 (2): 1102–10. PMID 2295603.
- Vignal A, Rahuel C, London J, et al. (1990). "A novel gene member of the human glycophorin A and B gene family. Molecular cloning and expression". Eur. J. Biochem. 191 (3): 619–625. doi:10.1111/j.1432-1033.1990.tb19166.x. PMID 2390989.
- Kudo S, Fukuda M (1994). "Contribution of gene conversion to the retention of the sequence for M blood group type determinant in glycophorin E gene". J. Biol. Chem. 269 (37): 22969–74. PMID 7521873.
- Onda M, Fukuda M (1995). "Detailed physical mapping of the genes encoding glycophorins A, B and E, as revealed by P1 plasmids containing human genomic DNA". Gene. 159 (2): 225–230. doi:10.1016/0378-1119(95)00075-H. PMID 7622054.
- Kudo S, Onda M, Fukuda M (1995). "Characterization of glycophorin A transcripts: control by the common erythroid-specific promoter and alternative usage of different polyadenylation signals". J. Biochem. 116 (1): 183–92. PMID 7798177.
- Huang CH, Chen Y, Blumenfeld OO (2000). "A novel St(a) glycophorin produced via gene conversion of pseudoexon III from glycophorin E to glycophorin A gene". Hum. Mutat. 15 (6): 533–540. doi:10.1002/1098-1004(200006)15:6<533::AID-HUMU5>3.0.CO;2-R. PMID 10862083.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Wang HY, Tang H, Shen CK, Wu CI (2004). "Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria parasites". Mol. Biol. Evol. 20 (11): 1795–1804. doi:10.1093/molbev/msg185. PMID 12949139.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
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