TUBGCP2: Difference between revisions

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Latest revision as of 12:27, 15 September 2017

Gamma-tubulin complex component 2 is a protein that in humans is encoded by the TUBGCP2 gene.^[1]^[2] It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

References

↑ Murphy SM, Urbani L, Stearns T (Jun 1998). "The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p". J Cell Biol. 141 (3): 663–74. doi:10.1083/jcb.141.3.663. PMC 2132743. PMID 9566967.
↑ "Entrez Gene: TUBGCP2 tubulin, gamma complex associated protein 2".

Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Hillman RT, Green RE, Brenner SE (2005). "An unappreciated role for RNA surveillance". Genome Biol. 5 (2): R8. doi:10.1186/gb-2004-5-2-r8. PMC 395752. PMID 14759258.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Takahashi M, Yamagiwa A, Nishimura T, et al. (2003). "Centrosomal Proteins CG-NAP and Kendrin Provide Microtubule Nucleation Sites by Anchoring γ-Tubulin Ring Complex". Mol. Biol. Cell. 13 (9): 3235–45. doi:10.1091/mbc.E02-02-0112. PMC 124155. PMID 12221128.
Murphy SM, Preble AM, Patel UK, et al. (2002). "GCP5 and GCP6: Two New Members of the Human γ-Tubulin Complex". Mol. Biol. Cell. 12 (11): 3340–52. doi:10.1091/mbc.12.11.3340. PMC 60259. PMID 11694571.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

[pmid9566967-1] Murphy SM, Urbani L, Stearns T (Jun 1998). "The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p". J Cell Biol. 141 (3): 663–74. doi:10.1083/jcb.141.3.663. PMC 2132743. PMID 9566967.

[entrez-2] "Entrez Gene: TUBGCP2 tubulin, gamma complex associated protein 2".

[1]

[2]

@@ Line 1: / Line 1: @@
+{{Infobox_gene}}
+'''Gamma-tubulin complex component 2''' is a [[protein]] that in humans is encoded by the ''TUBGCP2'' [[gene]].<ref name="pmid9566967">{{cite journal |vauthors=Murphy SM, Urbani L, Stearns T | title = The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p | journal = J Cell Biol | volume = 141 | issue = 3 | pages = 663–74 |date=Jun 1998 | pmid = 9566967 | pmc = 2132743 | doi =10.1083/jcb.141.3.663  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TUBGCP2 tubulin, gamma complex associated protein 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10844| accessdate = }}</ref>
+It is part of the gamma tubulin complex, which required for [[microtubule nucleation]] at the [[centrosome]].
+==See also==
+*[[Tubulin]]
+* [[TUBGCP3]]
+* [[TUBGCP4]]
+* [[TUBGCP5]]
+* [[TUBGCP6]]
+==References==
+{{reflist}}
+==Further reading==
+{{refbegin | 2}}
+{{PBB_Further_reading
+| citations =
+*{{cite journal  | author=Rush J |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046  |name-list-format=vanc| author2=Moritz A  | author3=Lee KA  | display-authors=3  | last4=Guo  | first4=Ailan  | last5=Goss  | first5=Valerie L  | last6=Spek  | first6=Erik J  | last7=Zhang  | first7=Hui  | last8=Zha  | first8=Xiang-Ming  | last9=Polakiewicz  | first9=Roberto D }}
+*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
+*{{cite journal  |vauthors=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8  | pmc=395752 }}
+*{{cite journal  | author=Bouwmeester T |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086  |name-list-format=vanc| author2=Bauch A  | author3=Ruffner H  | display-authors=3  | last4=Angrand  | first4=Pierre-Olivier  | last5=Bergamini  | first5=Giovanna  | last6=Croughton  | first6=Karen  | last7=Cruciat  | first7=Cristina  | last8=Eberhard  | first8=Dirk  | last9=Gagneur  | first9=Julien }}
+*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285  |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
+*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
+*{{cite journal  | author=Takahashi M |title=Centrosomal Proteins CG-NAP and Kendrin Provide Microtubule Nucleation Sites by Anchoring γ-Tubulin Ring Complex |journal=Mol. Biol. Cell |volume=13 |issue= 9 |pages= 3235–45 |year= 2003 |pmid= 12221128 |doi= 10.1091/mbc.E02-02-0112  | pmc=124155  |name-list-format=vanc| author2=Yamagiwa A  | author3=Nishimura T  | display-authors=3  | last4=Mukai  | first4=H  | last5=Ono  | first5=Y }}
+*{{cite journal  | author=Murphy SM |title=GCP5 and GCP6: Two New Members of the Human γ-Tubulin Complex |journal=Mol. Biol. Cell |volume=12 |issue= 11 |pages= 3340–52 |year= 2002 |pmid= 11694571 |doi=  10.1091/mbc.12.11.3340| pmc=60259  |name-list-format=vanc| author2=Preble AM  | author3=Patel UK  | display-authors=3  | last4=O'Connell  | first4=KL  | last5=Dias  | first5=DP  | last6=Moritz  | first6=M  | last7=Agard  | first7=D  | last8=Stults  | first8=JT  | last9=Stearns  | first9=T  }}
+*{{cite journal  | author=Suzuki Y |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |name-list-format=vanc| author2=Yoshitomo-Nakagawa K  | author3=Maruyama K  | display-authors=3  | last4=Suyama  | first4=Akira  | last5=Sugano  | first5=Sumio  }}
+*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
+*{{cite journal  | author=Adams MD |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3–174 |year= 1995 |pmid= 7566098 |doi=<!-- none available --> |url=http://www.columbia.edu/itc/biology/pollack/w4065/client_edit/readings/nature377_3.pdf | format=PDF  |name-list-format=vanc| author2=Kerlavage AR  | author3=Fleischmann RD  | display-authors=3  | last4=Fuldner  | first4=RA  | last5=Bult  | first5=CJ  | last6=Lee  | first6=NH  | last7=Kirkness  | first7=EF  | last8=Weinstock  | first8=KG  | last9=Gocayne  | first9=JD   }}
+}}
+{{refend}}
 <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
 {{PBB_Controls
@@ Line 8: / Line 40: @@
 }}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Tubulin, gamma complex associated protein 2
- | HGNCid = 18599
- | Symbol = TUBGCP2
- | AltSymbols =; GCP2; MGC138162; SPBC97; Spc97p
- | OMIM =
- | ECnumber =
- | Homologene = 55980
- | MGIid = 1921487
- | GeneAtlas_image1 = PBB_GE_TUBGCP2_202477_s_at_tn.png
- | GeneAtlas_image2 = PBB_GE_TUBGCP2_202476_s_at_tn.png
- | Function =
- | Component = {{GNF_GO|id=GO:0000922 |text = spindle pole}} {{GNF_GO|id=GO:0005815 |text = microtubule organizing center}} {{GNF_GO|id=GO:0005881 |text = cytoplasmic microtubule}}
- | Process = {{GNF_GO|id=GO:0000226 |text = microtubule cytoskeleton organization and biogenesis}} {{GNF_GO|id=GO:0006461 |text = protein complex assembly}} {{GNF_GO|id=GO:0007020 |text = microtubule nucleation}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 10844
-    | Hs_Ensembl = ENSG00000130640
-    | Hs_RefseqProtein = NP_006650
-    | Hs_RefseqmRNA = NM_006659
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 10
-    | Hs_GenLoc_start = 134943125
-    | Hs_GenLoc_end = 134975831
-    | Hs_Uniprot = Q9BSJ2
-    | Mm_EntrezGene = 74237
-    | Mm_Ensembl = ENSMUSG00000025474
-    | Mm_RefseqmRNA = NM_133755
-    | Mm_RefseqProtein = NP_598516
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 7
-    | Mm_GenLoc_start = 139847316
-    | Mm_GenLoc_end = 139887586
-    | Mm_Uniprot = Q3TIB7
-  }}
-}}
-'''Tubulin, gamma complex associated protein 2''', also known as '''TUBGCP2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TUBGCP2 tubulin, gamma complex associated protein 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10844| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
-==References==
-{{reflist|2}}
-==Further reading==
-{{refbegin | 2}}
-{{PBB_Further_reading
-| citations =
-*{{cite journal  | author=Rush J, Moritz A, Lee KA, ''et al.'' |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94-101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8 }}
-*{{cite journal  | author=Bouwmeester T, Bauch A, Ruffner H, ''et al.'' |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97-105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Takahashi M, Yamagiwa A, Nishimura T, ''et al.'' |title=Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. |journal=Mol. Biol. Cell |volume=13 |issue= 9 |pages= 3235-45 |year= 2003 |pmid= 12221128 |doi= 10.1091/mbc.E02-02-0112 }}
-*{{cite journal  | author=Murphy SM, Preble AM, Patel UK, ''et al.'' |title=GCP5 and GCP6: two new members of the human gamma-tubulin complex. |journal=Mol. Biol. Cell |volume=12 |issue= 11 |pages= 3340-52 |year= 2002 |pmid= 11694571 |doi=  }}
-*{{cite journal  | author=Murphy SM, Urbani L, Stearns T |title=The mammalian gamma-tubulin complex contains homologues of the yeast spindle pole body components spc97p and spc98p. |journal=J. Cell Biol. |volume=141 |issue= 3 |pages= 663-74 |year= 1998 |pmid= 9566967 |doi=  }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
-*{{cite journal  | author=Adams MD, Kerlavage AR, Fleischmann RD, ''et al.'' |title=Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence. |journal=Nature |volume=377 |issue= 6547 Suppl |pages= 3-174 |year= 1995 |pmid= 7566098 |doi=  }}
-}}
-{{refend}}
-{{protein-stub}}
+{{gene-10-stub}}
-{{WikiDoc Sources}}

TUBGCP2: Difference between revisions

Latest revision as of 12:27, 15 September 2017

See also

References

Further reading

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