SFRS5: Difference between revisions

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{{Infobox_gene}}
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'''Splicing factor, arginine/serine-rich 5''' is a [[protein]] that in humans is encoded by the ''SFRS5'' [[gene]].<ref name="pmid7686911">{{cite journal | vauthors = Diamond RH, Du K, Lee VM, Mohn KL, Haber BA, Tewari DS, Taub R | title = Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing | journal = The Journal of Biological Chemistry | volume = 268 | issue = 20 | pages = 15185–92 | date = July 1993 | pmid = 7686911 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SFRS5 splicing factor, arginine/serine-rich 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6430| accessdate = }}</ref>
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== References ==
{{GNF_Protein_box
{{reflist}}
| image = 
| image_source = 
| PDB =
| Name = Splicing factor, arginine/serine-rich 5
| HGNCid = 10787
| Symbol = SFRS5
| AltSymbols =; HRS; SRP40
| OMIM = 600914
| ECnumber = 
| Homologene = 87833
| MGIid = 
| GeneAtlas_image1 = PBB_GE_SFRS5_212266_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_SFRS5_203380_x_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003676 |text = nucleic acid binding}} {{GNF_GO|id=GO:0003723 |text = RNA binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006376 |text = mRNA splice site selection}} {{GNF_GO|id=GO:0006397 |text = mRNA processing}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6430
    | Hs_Ensembl = ENSG00000100650
    | Hs_RefseqProtein = NP_001034554
    | Hs_RefseqmRNA = NM_001039465
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 14
    | Hs_GenLoc_start = 69263370
    | Hs_GenLoc_end = 69308474
    | Hs_Uniprot = Q13243
    | Mm_EntrezGene = 622469
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = XM_886902
    | Mm_RefseqProtein = XP_891995
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
    | Mm_Uniprot = 
  }}
}}
'''Splicing factor, arginine/serine-rich 5''', also known as '''SFRS5''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SFRS5 splicing factor, arginine/serine-rich 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6430| accessdate = }}</ref>


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== Further reading ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Zahler AM, Lane WS, Stolk JA, Roth MB | title = SR proteins: a conserved family of pre-mRNA splicing factors | journal = Genes & Development | volume = 6 | issue = 5 | pages = 837–47 | date = May 1992 | pmid = 1577277 | doi = 10.1101/gad.6.5.837 }}
| citations =
* {{cite journal | vauthors = Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR | title = Identification and characterization of three members of the human SR family of pre-mRNA splicing factors | journal = The EMBO Journal | volume = 14 | issue = 17 | pages = 4336–49 | date = September 1995 | pmid = 7556075 | pmc = 394518 | doi =  }}
*{{cite journal | author=Zahler AM, Lane WS, Stolk JA, Roth MB |title=SR proteins: a conserved family of pre-mRNA splicing factors. |journal=Genes Dev. |volume=6 |issue= 5 |pages= 837-47 |year= 1992 |pmid= 1577277 |doi= }}
* {{cite journal | vauthors = Gui JF, Lane WS, Fu XD | title = A serine kinase regulates intracellular localization of splicing factors in the cell cycle | journal = Nature | volume = 369 | issue = 6482 | pages = 678–82 | date = June 1994 | pmid = 8208298 | doi = 10.1038/369678a0 }}
*{{cite journal | author=Screaton GR, Cáceres JF, Mayeda A, ''et al.'' |title=Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. |journal=EMBO J. |volume=14 |issue= 17 |pages= 4336-49 |year= 1995 |pmid= 7556075 |doi=  }}
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = April 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
*{{cite journal  | author=Diamond RH, Du K, Lee VM, ''et al.'' |title=Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing. |journal=J. Biol. Chem. |volume=268 |issue= 20 |pages= 15185-92 |year= 1993 |pmid= 7686911 |doi=  }}
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = April 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
*{{cite journal | author=Gui JF, Lane WS, Fu XD |title=A serine kinase regulates intracellular localization of splicing factors in the cell cycle. |journal=Nature |volume=369 |issue= 6482 |pages= 678-82 |year= 1994 |pmid= 8208298 |doi= 10.1038/369678a0 }}
* {{cite journal | vauthors = Snow BE, Heng HH, Shi XM, Zhou Y, Du K, Taub R, Tsui LC, McInnes RR | title = Expression analysis and chromosomal assignment of the human SFRS5/SRp40 gene | journal = Genomics | volume = 43 | issue = 2 | pages = 165–70 | date = July 1997 | pmid = 9244433 | doi = 10.1006/geno.1997.4794 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Du K, Taub R | title = Alternative splicing and structure of the human and mouse SFRS5/HRS/SRp40 genes | journal = Gene | volume = 204 | issue = 1-2 | pages = 243–9 | date = December 1997 | pmid = 9434190 | doi = 10.1016/S0378-1119(97)00552-0 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi= }}
* {{cite journal | vauthors = Blencowe BJ, Issner R, Nickerson JA, Sharp PA | title = A coactivator of pre-mRNA splicing | journal = Genes & Development | volume = 12 | issue = 7 | pages = 996–1009 | date = April 1998 | pmid = 9531537 | pmc = 316672 | doi = 10.1101/gad.12.7.996 }}
*{{cite journal | author=Snow BE, Heng HH, Shi XM, ''et al.'' |title=Expression analysis and chromosomal assignment of the human SFRS5/SRp40 gene. |journal=Genomics |volume=43 |issue= 2 |pages= 165-70 |year= 1997 |pmid= 9244433 |doi= 10.1006/geno.1997.4794 }}
* {{cite journal | vauthors = Papoutsopoulou S, Nikolakaki E, Chalepakis G, Kruft V, Chevaillier P, Giannakouros T | title = SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1 | journal = Nucleic Acids Research | volume = 27 | issue = 14 | pages = 2972–80 | date = July 1999 | pmid = 10390541 | pmc = 148514 | doi = 10.1093/nar/27.14.2972 }}
*{{cite journal | author=Du K, Taub R |title=Alternative splicing and structure of the human and mouse SFRS5/HRS/SRp40 genes. |journal=Gene |volume=204 |issue= 1-2 |pages= 243-9 |year= 1998 |pmid= 9434190 |doi= }}
* {{cite journal | vauthors = Guil S, Gattoni R, Carrascal M, Abián J, Stévenin J, Bach-Elias M | title = Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation | journal = Molecular and Cellular Biology | volume = 23 | issue = 8 | pages = 2927–41 | date = April 2003 | pmid = 12665590 | pmc = 152554 | doi = 10.1128/MCB.23.8.2927-2941.2003 }}
*{{cite journal | author=Blencowe BJ, Issner R, Nickerson JA, Sharp PA |title=A coactivator of pre-mRNA splicing. |journal=Genes Dev. |volume=12 |issue= 7 |pages= 996-1009 |year= 1998 |pmid= 9531537 |doi= }}
* {{cite journal | vauthors = Liu L, Amy V, Liu G, McKeehan WL | title = Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells | journal = In Vitro Cellular & Developmental Biology. Animal | volume = 38 | issue = 10 | pages = 582–94 | year = 2003 | pmid = 12762840 | pmc = 3225227 | doi = 10.1290/1543-706X(2002)38<582:NCIMAT>2.0.CO;2 }}
*{{cite journal | author=Papoutsopoulou S, Nikolakaki E, Chalepakis G, ''et al.'' |title=SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1. |journal=Nucleic Acids Res. |volume=27 |issue= 14 |pages= 2972-80 |year= 1999 |pmid= 10390541 |doi=  }}
* {{cite journal | vauthors = Li J, Hawkins IC, Harvey CD, Jennings JL, Link AJ, Patton JG | title = Regulation of alternative splicing by SRrp86 and its interacting proteins | journal = Molecular and Cellular Biology | volume = 23 | issue = 21 | pages = 7437–47 | date = November 2003 | pmid = 14559993 | pmc = 207616 | doi = 10.1128/MCB.23.21.7437-7447.2003 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = de Graaf K, Hekerman P, Spelten O, Herrmann A, Packman LC, Büssow K, Müller-Newen G, Becker W | title = Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors | journal = The Journal of Biological Chemistry | volume = 279 | issue = 6 | pages = 4612–24 | date = February 2004 | pmid = 14623875 | doi = 10.1074/jbc.M310794200 }}
*{{cite journal | author=Guil S, Gattoni R, Carrascal M, ''et al.'' |title=Roles of hnRNP A1, SR proteins, and p68 helicase in c-H-ras alternative splicing regulation. |journal=Mol. Cell. Biol. |volume=23 |issue= 8 |pages= 2927-41 |year= 2003 |pmid= 12665590 |doi= }}
* {{cite journal | vauthors = Hillman RT, Green RE, Brenner SE | title = An unappreciated role for RNA surveillance | journal = Genome Biology | volume = 5 | issue = 2 | pages = R8 | year = 2005 | pmid = 14759258 | pmc = 395752 | doi = 10.1186/gb-2004-5-2-r8 }}
*{{cite journal | author=Liu L, Amy V, Liu G, McKeehan WL |title=Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells. |journal=In Vitro Cell. Dev. Biol. Anim. |volume=38 |issue= 10 |pages= 582-94 |year= 2003 |pmid= 12762840 |doi= }}
* {{cite journal | vauthors = Ropers D, Ayadi L, Gattoni R, Jacquenet S, Damier L, Branlant C, Stévenin J | title = Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA | journal = The Journal of Biological Chemistry | volume = 279 | issue = 29 | pages = 29963–73 | date = July 2004 | pmid = 15123677 | doi = 10.1074/jbc.M404452200 }}
*{{cite journal | author=Li J, Hawkins IC, Harvey CD, ''et al.'' |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437-47 |year= 2003 |pmid= 14559993 |doi= }}
* {{cite journal | vauthors = Caputi M, Freund M, Kammler S, Asang C, Schaal H | title = A bidirectional SF2/ASF- and SRp40-dependent splicing enhancer regulates human immunodeficiency virus type 1 rev, env, vpu, and nef gene expression | journal = Journal of Virology | volume = 78 | issue = 12 | pages = 6517–26 | date = June 2004 | pmid = 15163745 | pmc = 416506 | doi = 10.1128/JVI.78.12.6517-6526.2004 }}
*{{cite journal | author=de Graaf K, Hekerman P, Spelten O, ''et al.'' |title=Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors. |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4612-24 |year= 2004 |pmid= 14623875 |doi= 10.1074/jbc.M310794200 }}
* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = August 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}
*{{cite journal | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8 }}
*{{cite journal | author=Ropers D, Ayadi L, Gattoni R, ''et al.'' |title=Differential effects of the SR proteins 9G8, SC35, ASF/SF2, and SRp40 on the utilization of the A1 to A5 splicing sites of HIV-1 RNA. |journal=J. Biol. Chem. |volume=279 |issue= 29 |pages= 29963-73 |year= 2004 |pmid= 15123677 |doi= 10.1074/jbc.M404452200 }}
*{{cite journal | author=Caputi M, Freund M, Kammler S, ''et al.'' |title=A bidirectional SF2/ASF- and SRp40-dependent splicing enhancer regulates human immunodeficiency virus type 1 rev, env, vpu, and nef gene expression. |journal=J. Virol. |volume=78 |issue= 12 |pages= 6517-26 |year= 2004 |pmid= 15163745 |doi= 10.1128/JVI.78.12.6517-6526.2004 }}
*{{cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, ''et al.'' |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130-5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
}}
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Latest revision as of 06:13, 11 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Splicing factor, arginine/serine-rich 5 is a protein that in humans is encoded by the SFRS5 gene.[1][2]

References

  1. ↑ Diamond RH, Du K, Lee VM, Mohn KL, Haber BA, Tewari DS, Taub R (July 1993). "Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing". The Journal of Biological Chemistry. 268 (20): 15185–92. PMID 7686911.
  2. ↑ "Entrez Gene: SFRS5 splicing factor, arginine/serine-rich 5".

Further reading

Retrieved from "https://www.wikidoc.org/index.php?title=SFRS5&oldid=1416464"