MT1E: Difference between revisions

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Latest revision as of 06:59, 4 September 2017

Metallothionein-1E is a protein that in humans is encoded by the MT1E gene.^[1]^[2]^[3]

References

↑ Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB (Oct 1984). "Human metallothionein genes are clustered on chromosome 16". Proc Natl Acad Sci U S A. 81 (17): 5494–8. doi:10.1073/pnas.81.17.5494. PMC 391732. PMID 6089206.
↑ Schmidt CJ, Jubier MF, Hamer DH (Jul 1985). "Structure and expression of two human metallothionein-I isoform genes and a related pseudogene". J Biol Chem. 260 (12): 7731–7. PMID 2581970.
↑ "Entrez Gene: MT1E metallothionein 1E".

West AK, Stallings R, Hildebrand CE, et al. (1991). "Human metallothionein genes: structure of the functional locus at 16q13". Genomics. 8 (3): 513–8. doi:10.1016/0888-7543(90)90038-V. PMID 2286373.
Le Beau MM, Diaz MO, Karin M, Rowley JD (1985). "Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia". Nature. 313 (6004): 709–11. doi:10.1038/313709a0. PMID 3856101.
Carter AD, Felber BK, Walling MJ, et al. (1985). "Duplicated heavy metal control sequences of the mouse metallothionein-I gene". Proc. Natl. Acad. Sci. U.S.A. 81 (23): 7392–6. doi:10.1073/pnas.81.23.7392. PMC 392152. PMID 6095291.
Kondo Y, Kuo SM, Lazo JS (1994). "Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum". J. Pharmacol. Exp. Ther. 270 (3): 1313–8. PMID 7932184.
Pauwels M, van Weyenbergh J, Soumillion A, et al. (1994). "Induction by zinc of specific metallothionein isoforms in human monocytes". Eur. J. Biochem. 220 (1): 105–10. doi:10.1111/j.1432-1033.1994.tb18603.x. PMID 8119276.
Vandeghinste N, Proost P, De Ley M (2000). "Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes". Cell. Mol. Biol. (Noisy-le-grand). 46 (2): 419–33. PMID 10774930.
Nguyen A, Jing Z, Mahoney PS, et al. (2000). "In vivo gene expression profile analysis of metallothionein in renal cell carcinoma". Cancer Lett. 160 (2): 133–40. doi:10.1016/S0304-3835(00)00534-6. PMID 11053642.
Oppermann B, Zhang W, Magabo K, Kantorow M (2001). "Identification and spatial analysis of metallothioneins expressed by the adult human lens". Invest. Ophthalmol. Vis. Sci. 42 (1): 188–93. PMC 2957813. PMID 11133866.
Garrett SH, Belcastro M, Sens MA, et al. (2001). "Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells". J. Toxicol. Environ. Health Part A. 64 (4): 343–55. doi:10.1080/152873901316981321. PMID 11693492.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042.
Hawse JR, Cumming JR, Oppermann B, et al. (2003). "Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses". Invest. Ophthalmol. Vis. Sci. 44 (2): 672–9. doi:10.1167/iovs.02-0018. PMC 2825746. PMID 12556398.
Sens D, Rossi M, Park S, et al. (2003). "Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2". J. Toxicol. Environ. Health Part A. 66 (21): 2031–46. doi:10.1080/713853980. PMID 14555400.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Sun NN, Fastje CD, Wong SS, et al. (2005). "Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line". Toxicology and industrial health. 19 (7–10): 157–63. doi:10.1191/0748233703th185oa. PMID 15747776.
Lederer CW, Torrisi A, Pantelidou M, et al. (2007). "Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis". BMC Genomics. 8: 26. doi:10.1186/1471-2164-8-26. PMC 1796866. PMID 17244347.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[pmid6089206-1] Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB (Oct 1984). "Human metallothionein genes are clustered on chromosome 16". Proc Natl Acad Sci U S A. 81 (17): 5494–8. doi:10.1073/pnas.81.17.5494. PMC 391732. PMID 6089206.

[pmid2581970-2] Schmidt CJ, Jubier MF, Hamer DH (Jul 1985). "Structure and expression of two human metallothionein-I isoform genes and a related pseudogene". J Biol Chem. 260 (12): 7731–7. PMID 2581970.

[entrez-3] "Entrez Gene: MT1E metallothionein 1E".

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
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+{{Infobox_gene}}
-{{GNF_Protein_box
+'''Metallothionein-1E''' is a [[protein]] that in humans is encoded by the ''MT1E'' [[gene]].<ref name="pmid6089206">{{cite journal |vauthors=Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB | title = Human metallothionein genes are clustered on chromosome 16 | journal = Proc Natl Acad Sci U S A | volume = 81 | issue = 17 | pages = 5494–8 |date=Oct 1984 | pmid = 6089206 | pmc = 391732 | doi =10.1073/pnas.81.17.5494  }}</ref><ref name="pmid2581970">{{cite journal |vauthors=Schmidt CJ, Jubier MF, Hamer DH | title = Structure and expression of two human metallothionein-I isoform genes and a related pseudogene | journal = J Biol Chem | volume = 260 | issue = 12 | pages = 7731–7 |date=Jul 1985 | pmid = 2581970 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MT1E metallothionein 1E| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4493| accessdate = }}</ref>
- | image = PBB_Protein_MT1E_image.jpg
- | image_source = [[Protein_Data_Bank|PDB]] rendering based on 1mhu.
- | PDB = {{PDB2|1mhu}}, {{PDB2|1mrb}}, {{PDB2|2mhu}}, {{PDB2|2mrt}}
- | Name = Metallothionein 1E
- | HGNCid = 7397
- | Symbol = MT1E
- | AltSymbols =; MT1; MTD
- | OMIM = 156351
- | ECnumber =
- | Homologene = 81614
- | MGIid = 97171
- | GeneAtlas_image1 = PBB_GE_MT1E_212859_x_at_tn.png
-  | Function = {{GNF_GO|id=GO:0005507 |text = copper ion binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0046870 |text = cadmium ion binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
- | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}}
- | Process = {{GNF_GO|id=GO:0008150 |text = biological_process}}
-  | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 4493
-    | Hs_Ensembl = ENSG00000169715
-    | Hs_RefseqProtein = NP_783316
-    | Hs_RefseqmRNA = NM_175617
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 16
-    | Hs_GenLoc_start = 55216888
-    | Hs_GenLoc_end = 55218525
-    | Hs_Uniprot = P04732
-    | Mm_EntrezGene = 17748
-    | Mm_Ensembl = ENSMUSG00000031765
-    | Mm_RefseqmRNA = NM_013602
-    | Mm_RefseqProtein = NP_038630
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 8
-    | Mm_GenLoc_start = 97068356
-    | Mm_GenLoc_end = 97069453
-    | Mm_Uniprot = P02802
-  }}
-}}
-'''Metallothionein 1E''', also known as '''MT1E''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: MT1E metallothionein 1E| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4493| accessdate = }}</ref>
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@@ Line 55: / Line 11: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=West AK, Stallings R, Hildebrand CE, ''et al.'' |title=Human metallothionein genes: structure of the functional locus at 16q13. |journal=Genomics |volume=8 |issue= 3 |pages= 513-8 |year= 1991 |pmid= 2286373 |doi=  }}
+*{{cite journal   |vauthors=West AK, Stallings R, Hildebrand CE, etal |title=Human metallothionein genes: structure of the functional locus at 16q13. |journal=Genomics |volume=8 |issue= 3 |pages= 513–8 |year= 1991 |pmid= 2286373 |doi=10.1016/0888-7543(90)90038-V  }}
-*{{cite journal  | author=Schmidt CJ, Jubier MF, Hamer DH |title=Structure and expression of two human metallothionein-I isoform genes and a related pseudogene. |journal=J. Biol. Chem. |volume=260 |issue= 12 |pages= 7731-7 |year= 1985 |pmid= 2581970 |doi=  }}
+*{{cite journal  |vauthors=Le Beau MM, Diaz MO, Karin M, Rowley JD |title=Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia. |journal=Nature |volume=313 |issue= 6004 |pages= 709–11 |year= 1985 |pmid= 3856101 |doi=10.1038/313709a0  }}
-*{{cite journal  | author=Le Beau MM, Diaz MO, Karin M, Rowley JD |title=Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia. |journal=Nature |volume=313 |issue= 6004 |pages= 709-11 |year= 1985 |pmid= 3856101 |doi=  }}
+*{{cite journal   |vauthors=Carter AD, Felber BK, Walling MJ, etal |title=Duplicated heavy metal control sequences of the mouse metallothionein-I gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 23 |pages= 7392–6 |year= 1985 |pmid= 6095291 |doi=10.1073/pnas.81.23.7392  | pmc=392152  }}
-*{{cite journal  | author=Karin M, Eddy RL, Henry WM, ''et al.'' |title=Human metallothionein genes are clustered on chromosome 16. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 17 |pages= 5494-8 |year= 1984 |pmid= 6089206 |doi=  }}
+*{{cite journal  |vauthors=Kondo Y, Kuo SM, Lazo JS |title=Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum. |journal=J. Pharmacol. Exp. Ther. |volume=270 |issue= 3 |pages= 1313–8 |year= 1994 |pmid= 7932184 |doi=  }}
-*{{cite journal  | author=Carter AD, Felber BK, Walling MJ, ''et al.'' |title=Duplicated heavy metal control sequences of the mouse metallothionein-I gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=81 |issue= 23 |pages= 7392-6 |year= 1985 |pmid= 6095291 |doi=  }}
+*{{cite journal   |vauthors=Pauwels M, van Weyenbergh J, Soumillion A, etal |title=Induction by zinc of specific metallothionein isoforms in human monocytes. |journal=Eur. J. Biochem. |volume=220 |issue= 1 |pages= 105–10 |year= 1994 |pmid= 8119276 |doi=10.1111/j.1432-1033.1994.tb18603.x  }}
-*{{cite journal  | author=Kondo Y, Kuo SM, Lazo JS |title=Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum. |journal=J. Pharmacol. Exp. Ther. |volume=270 |issue= 3 |pages= 1313-8 |year= 1994 |pmid= 7932184 |doi=  }}
+*{{cite journal  |vauthors=Vandeghinste N, Proost P, De Ley M |title=Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. |journal=Cell. Mol. Biol. (Noisy-le-grand) |volume=46 |issue= 2 |pages= 419–33 |year= 2000 |pmid= 10774930 |doi=  }}
-*{{cite journal  | author=Pauwels M, van Weyenbergh J, Soumillion A, ''et al.'' |title=Induction by zinc of specific metallothionein isoforms in human monocytes. |journal=Eur. J. Biochem. |volume=220 |issue= 1 |pages= 105-10 |year= 1994 |pmid= 8119276 |doi=  }}
+*{{cite journal   |vauthors=Nguyen A, Jing Z, Mahoney PS, etal |title=In vivo gene expression profile analysis of metallothionein in renal cell carcinoma. |journal=Cancer Lett. |volume=160 |issue= 2 |pages= 133–40 |year= 2000 |pmid= 11053642 |doi=10.1016/S0304-3835(00)00534-6  }}
-*{{cite journal  | author=Vandeghinste N, Proost P, De Ley M |title=Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. |journal=Cell. Mol. Biol. (Noisy-le-grand) |volume=46 |issue= 2 |pages= 419-33 |year= 2000 |pmid= 10774930 |doi=  }}
+*{{cite journal  |vauthors=Oppermann B, Zhang W, Magabo K, Kantorow M |title=Identification and spatial analysis of metallothioneins expressed by the adult human lens. |journal=Invest. Ophthalmol. Vis. Sci. |volume=42 |issue= 1 |pages= 188–93 |year= 2001 |pmid= 11133866 |doi=  | pmc=2957813  }}
-*{{cite journal  | author=Nguyen A, Jing Z, Mahoney PS, ''et al.'' |title=In vivo gene expression profile analysis of metallothionein in renal cell carcinoma. |journal=Cancer Lett. |volume=160 |issue= 2 |pages= 133-40 |year= 2000 |pmid= 11053642 |doi=  }}
+*{{cite journal   |vauthors=Garrett SH, Belcastro M, Sens MA, etal |title=Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells |journal=J. Toxicol. Environ. Health Part A |volume=64 |issue= 4 |pages= 343–55 |year= 2001 |pmid= 11693492 |doi=10.1080/152873901316981321  }}
-*{{cite journal  | author=Oppermann B, Zhang W, Magabo K, Kantorow M |title=Identification and spatial analysis of metallothioneins expressed by the adult human lens. |journal=Invest. Ophthalmol. Vis. Sci. |volume=42 |issue= 1 |pages= 188-93 |year= 2001 |pmid= 11133866 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Garrett SH, Belcastro M, Sens MA, ''et al.'' |title=Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells. |journal=J. Toxicol. Environ. Health Part A |volume=64 |issue= 4 |pages= 343-55 |year= 2001 |pmid= 11693492 |doi=  }}
+*{{cite journal   |vauthors=Izmailova E, Bertley FM, Huang Q, etal |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191–7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Hawse JR, Cumming JR, Oppermann B, etal |title=Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue= 2 |pages= 672–9 |year= 2003 |pmid= 12556398 |doi=10.1167/iovs.02-0018  | pmc=2825746  }}
-*{{cite journal  | author=Izmailova E, Bertley FM, Huang Q, ''et al.'' |title=HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. |journal=Nat. Med. |volume=9 |issue= 2 |pages= 191-7 |year= 2003 |pmid= 12539042 |doi= 10.1038/nm822 }}
+*{{cite journal   |vauthors=Sens D, Rossi M, Park S, etal |title=Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2 |journal=J. Toxicol. Environ. Health Part A |volume=66 |issue= 21 |pages= 2031–46 |year= 2003 |pmid= 14555400 |doi=10.1080/713853980  }}
-*{{cite journal  | author=Hawse JR, Cumming JR, Oppermann B, ''et al.'' |title=Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses. |journal=Invest. Ophthalmol. Vis. Sci. |volume=44 |issue= 2 |pages= 672-9 |year= 2003 |pmid= 12556398 |doi=  }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Sens D, Rossi M, Park S, ''et al.'' |title=Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2. |journal=J. Toxicol. Environ. Health Part A |volume=66 |issue= 21 |pages= 2031-46 |year= 2003 |pmid= 14555400 |doi=  }}
+*{{cite journal   |vauthors=Sun NN, Fastje CD, Wong SS, etal |title=Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line |journal=Toxicology and industrial health |volume=19 |issue= 7–10 |pages= 157–63 |year= 2005 |pmid= 15747776 |doi=10.1191/0748233703th185oa  }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Lederer CW, Torrisi A, Pantelidou M, etal |title=Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis |journal=BMC Genomics |volume=8|pages= 26 |year= 2007 |pmid= 17244347 |doi= 10.1186/1471-2164-8-26  | pmc=1796866 }}
-*{{cite journal  | author=Sun NN, Fastje CD, Wong SS, ''et al.'' |title=Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line. |journal=Toxicology and industrial health |volume=19 |issue= 7-10 |pages= 157-63 |year= 2005 |pmid= 15747776 |doi=  }}
-*{{cite journal  | author=Lederer CW, Torrisi A, Pantelidou M, ''et al.'' |title=Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. |journal=BMC Genomics |volume=8 |issue=  |pages= 26 |year= 2007 |pmid= 17244347 |doi= 10.1186/1471-2164-8-26 }}
 }}
 {{refend}}
+{{PDB Gallery|geneid=4493}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
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+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
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+| update_citations = yes
+}}
-{{protein-stub}}
+{{gene-16-stub}}
-{{WikiDoc Sources}}

MT1E: Difference between revisions

Latest revision as of 06:59, 4 September 2017

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