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{{Underlinked|date=May 2016}}
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{{Infobox_gene}}
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'''Carcinoembryonic antigen-related cell adhesion molecule 7''' is a [[protein]] that in humans is encoded by the ''CEACAM7'' [[gene]].<ref name="pmid7806520">{{cite journal | vauthors = Thompson J, Zimmermann W, Nollau P, Neumaier M, Weber-Arden J, Schrewe H, Craig I, Willcocks T | title = CGM2, a member of the carcinoembryonic antigen gene family is down-regulated in colorectal carcinomas | journal = J Biol Chem | volume = 269 | issue = 52 | pages = 32924–31 |date=Jan 1995 | pmid = 7806520 | pmc =  | doi =  }}</ref><ref name="pmid9135022">{{cite journal | vauthors = Thompson J, Seitz M, Chastre E, Ditter M, Aldrian C, Gespach C, Zimmermann W | title = Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis | journal = Cancer Res | volume = 57 | issue = 9 | pages = 1776–84 |date=May 1997 | pmid = 9135022 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1087| accessdate = }}</ref>
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| image = 
| image_source = 
| PDB =
| Name = Carcinoembryonic antigen-related cell adhesion molecule 7
| HGNCid = 1819
| Symbol = CEACAM7
| AltSymbols =; CEA; CGM2
| OMIM =
| ECnumber =
| Homologene = 48476
| MGIid =
| GeneAtlas_image1 = PBB_GE_CEACAM7_211848_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_CEACAM7_206198_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_CEACAM7_206199_at_tn.png
  | Function = {{GNF_GO|id=GO:0048503 |text = GPI anchor binding}}
  | Component = {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 1087
    | Hs_Ensembl = ENSG00000007306
    | Hs_RefseqProtein = NP_008821
    | Hs_RefseqmRNA = NM_006890
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 19
    | Hs_GenLoc_start = 46869073
    | Hs_GenLoc_end = 46883936
    | Hs_Uniprot = Q14002
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA =
    | Mm_RefseqProtein =
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    | Mm_GenLoc_chr =
    | Mm_GenLoc_start =
    | Mm_GenLoc_end =   
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'''Carcinoembryonic antigen-related cell adhesion molecule 7''', also known as '''CEACAM7''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1087| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==External links==
* {{UCSC gene info|CEACAM7}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Douard R, Wind P, Sales JP, ''et al.'' |title=Long-term prognostic value of detection of circulating colorectal cancer cells using CGM2 reverse transcriptase-polymerase chain reaction assay. |journal=Surgery |volume=139 |issue= 4 |pages= 556-62 |year= 2006 |pmid= 16627067 |doi= 10.1016/j.surg.2005.09.025 }}
*{{cite journal  | vauthors=Douard R, Wind P, Sales JP |title=Long-term prognostic value of detection of circulating colorectal cancer cells using CGM2 reverse transcriptase-polymerase chain reaction assay. |journal=Surgery |volume=139 |issue= 4 |pages= 556–62 |year= 2006 |pmid= 16627067 |doi= 10.1016/j.surg.2005.09.025 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819-24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 }}
*{{cite journal  | vauthors=Zhang Z, Henzel WJ |title=Signal peptide prediction based on analysis of experimentally verified cleavage sites. |journal=Protein Sci. |volume=13 |issue= 10 |pages= 2819–24 |year= 2005 |pmid= 15340161 |doi= 10.1110/ps.04682504 | pmc=2286551 }}
*{{cite journal  | author=Grimwood J, Gordon LA, Olsen A, ''et al.'' |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529-35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 }}
*{{cite journal  | vauthors=Grimwood J, Gordon LA, Olsen A |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Schölzel S, Zimmermann W, Schwarzkopf G, ''et al.'' |title=Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. |journal=Am. J. Pathol. |volume=156 |issue= 2 |pages= 595-605 |year= 2000 |pmid= 10666389 |doi=  }}
*{{cite journal  | vauthors=Schölzel S, Zimmermann W, Schwarzkopf G |title=Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. |journal=Am. J. Pathol. |volume=156 |issue= 2 |pages= 595–605 |year= 2000 |pmid= 10666389 |doi=  10.1016/S0002-9440(10)64764-5| pmc=1850034  |display-authors=etal}}
*{{cite journal  | author=Frängsmyr L, Baranov V, Hammarström S |title=Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat. |journal=Tumour Biol. |volume=20 |issue= 5 |pages= 277-92 |year= 1999 |pmid= 10436421 |doi=  }}
*{{cite journal  | vauthors=Frängsmyr L, Baranov V, Hammarström S |title=Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat. |journal=Tumour Biol. |volume=20 |issue= 5 |pages= 277–92 |year= 1999 |pmid= 10436421 |doi=10.1159/000030075 }}
*{{cite journal  | author=Kinugasa T, Kuroki M, Takeo H, ''et al.'' |title=Expression of four CEA family antigens (CEA, NCA, BGP and CGM2) in normal and cancerous gastric epithelial cells: up-regulation of BGP and CGM2 in carcinomas. |journal=Int. J. Cancer |volume=76 |issue= 1 |pages= 148-53 |year= 1998 |pmid= 9533775 |doi= }}
*{{cite journal  | vauthors=Kinugasa T, Kuroki M, Takeo H |title=Expression of four CEA family antigens (CEA, NCA, BGP and CGM2) in normal and cancerous gastric epithelial cells: up-regulation of BGP and CGM2 in carcinomas. |journal=Int. J. Cancer |volume=76 |issue= 1 |pages= 148–53 |year= 1998 |pmid= 9533775 |doi=10.1002/(SICI)1097-0215(19980330)76:1<148::AID-IJC23>3.0.CO;2-7 |display-authors=etal}}
*{{cite journal  | author=Thompson J, Seitz M, Chastre E, ''et al.'' |title=Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis. |journal=Cancer Res. |volume=57 |issue= 9 |pages= 1776-84 |year= 1997 |pmid= 9135022 |doi= }}
*{{cite journal  | vauthors=Thompson JA, Mauch EM, Chen FS |title=Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons. |journal=Biochem. Biophys. Res. Commun. |volume=158 |issue= 3 |pages= 996–1004 |year= 1989 |pmid= 2537643 |doi=10.1016/0006-291X(89)92821-0 |display-authors=etal}}
*{{cite journal  | author=Thompson J, Zimmermann W, Nollau P, ''et al.'' |title=CGM2, a member of the carcinoembryonic antigen gene family is down-regulated in colorectal carcinomas. |journal=J. Biol. Chem. |volume=269 |issue= 52 |pages= 32924-31 |year= 1995 |pmid= 7806520 |doi= }}
*{{cite journal  | vauthors=Khan WN, Frängsmyr L, Teglund S |title=Identification of three new genes and estimation of the size of the carcinoembryonic antigen family. |journal=Genomics |volume=14 |issue= 2 |pages= 384–90 |year= 1992 |pmid= 1427854 |doi=10.1016/S0888-7543(05)80230-7 |display-authors=etal}}
*{{cite journal  | author=Thompson JA, Mauch EM, Chen FS, ''et al.'' |title=Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons. |journal=Biochem. Biophys. Res. Commun. |volume=158 |issue= 3 |pages= 996-1004 |year= 1989 |pmid= 2537643 |doi=  }}
*{{cite journal  | author=Khan WN, Frängsmyr L, Teglund S, ''et al.'' |title=Identification of three new genes and estimation of the size of the carcinoembryonic antigen family. |journal=Genomics |volume=14 |issue= 2 |pages= 384-90 |year= 1992 |pmid= 1427854 |doi=  }}
}}
}}
{{refend}}
{{refend}}


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{{gene-19-stub}}

Latest revision as of 09:31, 30 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

n/a

n/a

RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Carcinoembryonic antigen-related cell adhesion molecule 7 is a protein that in humans is encoded by the CEACAM7 gene.[1][2][3]


References

  1. ↑ Thompson J, Zimmermann W, Nollau P, Neumaier M, Weber-Arden J, Schrewe H, Craig I, Willcocks T (Jan 1995). "CGM2, a member of the carcinoembryonic antigen gene family is down-regulated in colorectal carcinomas". J Biol Chem. 269 (52): 32924–31. PMID 7806520.
  2. ↑ Thompson J, Seitz M, Chastre E, Ditter M, Aldrian C, Gespach C, Zimmermann W (May 1997). "Down-regulation of carcinoembryonic antigen family member 2 expression is an early event in colorectal tumorigenesis". Cancer Res. 57 (9): 1776–84. PMID 9135022.
  3. ↑ "Entrez Gene: CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7".

External links

Further reading



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