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{{Infobox_gene}}
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'''Ras-related protein Rab-3C''' is a [[protein]] that in humans is encoded by the ''RAB3C'' [[gene]].<ref name="pmid12296628">{{cite journal | vauthors = Cheng H, Ma Y, Ni X, Jiang M, Luo Y, Ying K, Xie Y, Ma Y | title = Cloning, mapping, and characterization of the human Rab3C gene | journal = Biochemical Genetics | volume = 40 | issue = 7-8 | pages = 263–72 | date = Aug 2002 | pmid = 12296628 | pmc = | doi = 10.1023/A:1019834901190 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB3C RAB3C, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115827| accessdate = }}</ref>
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== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = RAB3C, member RAS oncogene family
| HGNCid = 30269
| Symbol = RAB3C
| AltSymbols =;
| OMIM = 
| ECnumber = 
| Homologene = 23420
| MGIid = 1914545
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}}{{GNF_GO|id=GO:0005515 |text = protein binding}}{{GNF_GO|id=GO:0005525 |text = GTP binding}}
| Component = {{GNF_GO|id=GO:0008021 |text = synaptic vesicle}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0015031 |text = protein transport}} {{GNF_GO|id=GO:0017157 |text = regulation of exocytosis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 115827
    | Hs_Ensembl = ENSG00000152932
    | Hs_RefseqProtein = NP_612462
    | Hs_RefseqmRNA = NM_138453
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 57914671
    | Hs_GenLoc_end = 58190970
    | Hs_Uniprot = Q96E17
    | Mm_EntrezGene = 67295
    | Mm_Ensembl = ENSMUSG00000021700
    | Mm_RefseqmRNA = XM_975497
    | Mm_RefseqProtein = XP_980591
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 13
    | Mm_GenLoc_start = 111181960
    | Mm_GenLoc_end = 111400980
    | Mm_Uniprot = Q3TU26
  }}
}}
'''RAB3C, member RAS oncogene family''', also known as '''RAB3C''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB3C RAB3C, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115827| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Rab3C has been show to interact with [[ZWINT]].<ref name="pmid18625232">{{cite journal | vauthors = van Vlijmen T, Vleugel M, Evers M, Mohammed S, Wulf PS, Heck AJ, Hoogenraad CC, van der Sluijs P | title = A unique residue in rab3c determines the interaction with novel binding protein Zwint-1 | journal = FEBS Letters | volume = 582 | issue = 19 | pages = 2838–42 | date = Aug 2008 | pmid = 18625232 | doi = 10.1016/j.febslet.2008.07.012 }}</ref>
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| summary_text =  
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==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Matsumoto M, Miki T, Shibasaki T, Kawaguchi M, Shinozaki H, Nio J, Saraya A, Koseki H, Miyazaki M, Iwanaga T, Seino S | title = Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 22 | pages = 8313–8 | date = Jun 2004 | pmid = 15159548 | pmc = 420391 | doi = 10.1073/pnas.0306709101 }}
| citations =
* {{cite journal | vauthors = Fukuda M | title = Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2 | journal = The Journal of Biological Chemistry | volume = 278 | issue = 17 | pages = 15373–80 | date = Apr 2003 | pmid = 12578829 | doi = 10.1074/jbc.M212341200 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
* {{cite journal | vauthors = Schlüter OM, Khvotchev M, Jahn R, Südhof TC | title = Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion | journal = The Journal of Biological Chemistry | volume = 277 | issue = 43 | pages = 40919–29 | date = Oct 2002 | pmid = 12167638 | doi = 10.1074/jbc.M203704200 }}
*{{cite journal  | author=Matsumoto M, Miki T, Shibasaki T, ''et al.'' |title=Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 22 |pages= 8313-8 |year= 2004 |pmid= 15159548 |doi= 10.1073/pnas.0306709101 }}
* {{cite journal | vauthors = Uphues I, Chern Y, Eckel J | title = Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats | journal = FEBS Letters | volume = 377 | issue = 2 | pages = 109–12 | date = Dec 1995 | pmid = 8543030 | doi = 10.1016/0014-5793(95)01315-6 }}
*{{cite journal | author=Fukuda M |title=Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. |journal=J. Biol. Chem. |volume=278 |issue= 17 |pages= 15373-80 |year= 2003 |pmid= 12578829 |doi= 10.1074/jbc.M212341200 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Cheng H, Ma Y, Ni X, ''et al.'' |title=Cloning, mapping, and characterization of the human Rab3C gene. |journal=Biochem. Genet. |volume=40 |issue= 7-8 |pages= 263-72 |year= 2003 |pmid= 12296628 |doi=  }}
*{{cite journal  | author=Schlüter OM, Khvotchev M, Jahn R, Südhof TC |title=Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion. |journal=J. Biol. Chem. |volume=277 |issue= 43 |pages= 40919-29 |year= 2002 |pmid= 12167638 |doi= 10.1074/jbc.M203704200 }}
*{{cite journal | author=Uphues I, Chern Y, Eckel J |title=Insulin-dependent translocation of the small GTP-binding protein rab3C in cardiac muscle: studies on insulin-resistant Zucker rats. |journal=FEBS Lett. |volume=377 |issue= 2 |pages= 109-12 |year= 1996 |pmid= 8543030 |doi= }}
}}
{{refend}}
{{refend}}


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Latest revision as of 06:40, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Wikidata
View/Edit Human

Ras-related protein Rab-3C is a protein that in humans is encoded by the RAB3C gene.[1][2]

Interactions

Rab3C has been show to interact with ZWINT.[3]

References

  1. ↑ Cheng H, Ma Y, Ni X, Jiang M, Luo Y, Ying K, Xie Y, Ma Y (Aug 2002). "Cloning, mapping, and characterization of the human Rab3C gene". Biochemical Genetics. 40 (7–8): 263–72. doi:10.1023/A:1019834901190. PMID 12296628.
  2. ↑ "Entrez Gene: RAB3C RAB3C, member RAS oncogene family".
  3. ↑ van Vlijmen T, Vleugel M, Evers M, Mohammed S, Wulf PS, Heck AJ, Hoogenraad CC, van der Sluijs P (Aug 2008). "A unique residue in rab3c determines the interaction with novel binding protein Zwint-1". FEBS Letters. 582 (19): 2838–42. doi:10.1016/j.febslet.2008.07.012. PMID 18625232.

Further reading


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