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{{ | '''Histone H2B type 1-J''' is a [[protein]] that in humans is encoded by the ''HIST1H2BJ'' [[gene]].<ref name="pmid6647026">{{cite journal |vauthors=Zhong R, Roeder RG, Heintz N | title = The primary structure and expression of four cloned human histone genes | journal = Nucleic Acids Res | volume = 11 | issue = 21 | pages = 7409–7425 |date=Jan 1984 | pmid = 6647026 | pmc = 326492 | doi =10.1093/nar/11.21.7409 }}</ref><ref name="pmid12408966">{{cite journal |vauthors=Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ | title = The human and mouse replication-dependent histone genes | journal = Genomics | volume = 80 | issue = 5 | pages = 487–498 |date=Oct 2002 | pmid = 12408966 | pmc = | doi =10.1016/S0888-7543(02)96850-3 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: HIST1H2BJ histone cluster 1, H2bj| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8970| accessdate = }}</ref> | ||
}} | |||
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| summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.<ref name="entrez" | | summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.<ref name="entrez" /> | ||
}} | }} | ||
==References== | ==References== | ||
{{reflist | {{reflist}} | ||
==Further reading== | ==Further reading== | ||
{{refbegin | 2}} | {{refbegin | 2}} | ||
{{PBB_Further_reading | {{PBB_Further_reading | ||
| citations = | | citations = | ||
*{{cite journal | | *{{cite journal |vauthors=Alnemri ES, Litwack G |title=Glucocorticoid-induced lymphocytolysis is not mediated by an induced endonuclease |journal=J. Biol. Chem. |volume=264 |issue= 7 |pages= 4104–11 |year= 1989 |pmid= 2917990 |doi= }} | ||
*{{cite journal | author= | *{{cite journal | author=Frohm M |title=Biochemical and antibacterial analysis of human wound and blister fluid |journal=Eur. J. Biochem. |volume=237 |issue= 1 |pages= 86–92 |year= 1996 |pmid= 8620898 |doi=10.1111/j.1432-1033.1996.0086n.x |name-list-format=vanc| author2=Gunne H | author3=Bergman AC | display-authors=3 | last4=Agerberth | first4=Birgitta | last5=Bergman | first5=Tomas | last6=Boman | first6=Anita | last7=Liden | first7=Sture | last8=Jornvall | first8=Hans | last9=Boman | first9=Hans G. }} | ||
*{{cite journal |vauthors=Albig W, Doenecke D |title=The human histone gene cluster at the D6S105 locus |journal=Hum. Genet. |volume=101 |issue= 3 |pages= 284–294 |year= 1998 |pmid= 9439656 |doi=10.1007/s004390050630 }} | |||
*{{cite journal | | *{{cite journal |vauthors=El Kharroubi A, Piras G, Zensen R, Martin MA |title=Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter |journal=Mol. Cell. Biol. |volume=18 |issue= 5 |pages= 2535–44 |year= 1998 |pmid= 9566873 |doi= 10.1128/mcb.18.5.2535| pmc=110633 }} | ||
*{{cite journal | | *{{cite journal | author=Albig W |title=The human H2A and H2B histone gene complement |journal=Biol. Chem. |volume=380 |issue= 1 |pages= 7–18 |year= 1999 |pmid= 10064132 |doi=10.1515/BC.1999.002 |name-list-format=vanc| author2=Trappe R | author3=Kardalinou E | display-authors=3 | last4=Eick | first4=S. | last5=Doenecke | first5=D. }} | ||
*{{cite journal | author=Albig W | *{{cite journal |vauthors=Ahn J, Gruen JR |title=The genomic organization of the histone clusters on human 6p21.3 |journal=Mamm. Genome |volume=10 |issue= 7 |pages= 768–770 |year= 1999 |pmid= 10384058 |doi=10.1007/s003359901089 }} | ||
*{{cite journal | author=Deng L |title=Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones |journal=Virology |volume=277 |issue= 2 |pages= 278–295 |year= 2001 |pmid= 11080476 |doi= 10.1006/viro.2000.0593 |name-list-format=vanc| author2=de la Fuente C | author3=Fu P | display-authors=3 | last4=Wang | first4=L | last5=Donnelly | first5=R | last6=Wade | first6=JD | last7=Lambert | first7=P | last8=Li | first8=H | last9=Lee | first9=CG }} | |||
*{{cite journal | | *{{cite journal | author=Deng L |title=Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA |journal=Virology |volume=289 |issue= 2 |pages= 312–326 |year= 2001 |pmid= 11689053 |doi= 10.1006/viro.2001.1129 |name-list-format=vanc| author2=Wang D | author3=de la Fuente C | display-authors=3 | last4=Wang | first4=L | last5=Li | first5=H | last6=Lee | first6=CG | last7=Donnelly | first7=R | last8=Wade | first8=JD | last9=Lambert | first9=P }} | ||
*{{cite journal | author=Deng L | *{{cite journal | author=Galasinski SC |title=Global regulation of post-translational modifications on core histones |journal=J. Biol. Chem. |volume=277 |issue= 4 |pages= 2579–2588 |year= 2002 |pmid= 11709551 |doi= 10.1074/jbc.M107894200 |name-list-format=vanc| author2=Louie DF | author3=Gloor KK | display-authors=3 | last4=Resing | first4=KA | last5=Ahn | first5=NG }} | ||
*{{cite journal | author=Weinmann AS |title=Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis |journal=Genes Dev. |volume=16 |issue= 2 |pages= 235–244 |year= 2002 |pmid= 11799066 |doi= 10.1101/gad.943102 | pmc=155318 |name-list-format=vanc| author2=Yan PS | author3=Oberley MJ | display-authors=3 | last4=Huang | first4=TH | last5=Farnham | first5=PJ }} | |||
*{{cite journal | author= | *{{cite journal | author=Kim HS |title=Endotoxin-neutralizing antimicrobial proteins of the human placenta |journal=J. Immunol. |volume=168 |issue= 5 |pages= 2356–64 |year= 2002 |pmid= 11859126 |doi= 10.4049/jimmunol.168.5.2356|name-list-format=vanc| author2=Cho JH | author3=Park HW | display-authors=3 | last4=Yoon | first4=H | last5=Kim | first5=MS | last6=Kim | first6=SC }} | ||
*{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }} | |||
*{{cite journal | author= | *{{cite journal |vauthors=Giampuzzi M, Oleggini R, Di Donato A |title=Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved |journal=Biochim. Biophys. Acta |volume=1647 |issue= 1–2 |pages= 245–51 |year= 2003 |pmid= 12686141 |doi= 10.1016/s1570-9639(03)00059-1}} | ||
*{{cite journal | author=Cheung WL |title=Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase |journal=Cell |volume=113 |issue= 4 |pages= 507–517 |year= 2003 |pmid= 12757711 |doi=10.1016/S0092-8674(03)00355-6 |name-list-format=vanc| author2=Ajiro K | author3=Samejima K | display-authors=3 | last4=Kloc | first4=Malgorzata | last5=Cheung | first5=Peter | last6=Mizzen | first6=Craig A. | last7=Beeser | first7=Alexander | last8=Etkin | first8=Laurence D. | last9=Chernoff | first9=Jonathan }} | |||
*{{cite journal | author=Tollin M |title=Antimicrobial peptides in the first line defence of human colon mucosa |journal=Peptides |volume=24 |issue= 4 |pages= 523–530 |year= 2004 |pmid= 12860195 |doi=10.1016/S0196-9781(03)00114-1 |name-list-format=vanc| author2=Bergman P | author3=Svenberg T | display-authors=3 | last4=Jörnvall | first4=H | last5=Gudmundsson | first5=GH | last6=Agerberth | first6=B }} | |||
*{{cite journal | author= | *{{cite journal | author=Mungall AJ |title=The DNA sequence and analysis of human chromosome 6 |journal=Nature |volume=425 |issue= 6960 |pages= 805–811 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055 |name-list-format=vanc| author2=Palmer SA | author3=Sims SK | display-authors=3 | last4=Edwards | first4=C. A. | last5=Ashurst | first5=J. L. | last6=Wilming | first6=L. | last7=Jones | first7=M. C. | last8=Horton | first8=R. | last9=Hunt | first9=S. E. }} | ||
*{{cite journal |vauthors=Lusic M, Marcello A, Cereseto A, Giacca M |title=Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter |journal=EMBO J. |volume=22 |issue= 24 |pages= 6550–6561 |year= 2004 |pmid= 14657027 |doi= 10.1093/emboj/cdg631 | pmc=291826 }} | |||
*{{cite journal | author= | *{{cite journal |vauthors=Howell SJ, Wilk D, Yadav SP, Bevins CL |title=Antimicrobial polypeptides of the human colonic epithelium |journal=Peptides |volume=24 |issue= 11 |pages= 1763–1770 |year= 2004 |pmid= 15019208 |doi= 10.1016/j.peptides.2003.07.028 }} | ||
*{{cite journal | | |||
}} | }} | ||
{{refend}} | {{refend}} | ||
{{PDB Gallery|geneid=8970}} | |||
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{{ | {{gene-6-stub}} | ||
Latest revision as of 13:39, 31 August 2017
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| External IDs | GeneCards: [1] | ||||||
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| Species | Human | Mouse | |||||
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| RefSeq (mRNA) |
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| Location (UCSC) | n/a | n/a | |||||
| PubMed search | n/a | n/a | |||||
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Histone H2B type 1-J is a protein that in humans is encoded by the HIST1H2BJ gene.[1][2][3]
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.[3]
References
- ↑ Zhong R, Roeder RG, Heintz N (Jan 1984). "The primary structure and expression of four cloned human histone genes". Nucleic Acids Res. 11 (21): 7409–7425. doi:10.1093/nar/11.21.7409. PMC 326492. PMID 6647026.
- ↑ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–498. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966.
- ↑ 3.0 3.1 "Entrez Gene: HIST1H2BJ histone cluster 1, H2bj".
Further reading
- Alnemri ES, Litwack G (1989). "Glucocorticoid-induced lymphocytolysis is not mediated by an induced endonuclease". J. Biol. Chem. 264 (7): 4104–11. PMID 2917990.
- Frohm M, Gunne H, Bergman AC, et al. (1996). "Biochemical and antibacterial analysis of human wound and blister fluid". Eur. J. Biochem. 237 (1): 86–92. doi:10.1111/j.1432-1033.1996.0086n.x. PMID 8620898.
- Albig W, Doenecke D (1998). "The human histone gene cluster at the D6S105 locus". Hum. Genet. 101 (3): 284–294. doi:10.1007/s004390050630. PMID 9439656.
- El Kharroubi A, Piras G, Zensen R, Martin MA (1998). "Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter". Mol. Cell. Biol. 18 (5): 2535–44. doi:10.1128/mcb.18.5.2535. PMC 110633. PMID 9566873.
- Albig W, Trappe R, Kardalinou E, et al. (1999). "The human H2A and H2B histone gene complement". Biol. Chem. 380 (1): 7–18. doi:10.1515/BC.1999.002. PMID 10064132.
- Ahn J, Gruen JR (1999). "The genomic organization of the histone clusters on human 6p21.3". Mamm. Genome. 10 (7): 768–770. doi:10.1007/s003359901089. PMID 10384058.
- Deng L, de la Fuente C, Fu P, et al. (2001). "Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones". Virology. 277 (2): 278–295. doi:10.1006/viro.2000.0593. PMID 11080476.
- Deng L, Wang D, de la Fuente C, et al. (2001). "Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA". Virology. 289 (2): 312–326. doi:10.1006/viro.2001.1129. PMID 11689053.
- Galasinski SC, Louie DF, Gloor KK, et al. (2002). "Global regulation of post-translational modifications on core histones". J. Biol. Chem. 277 (4): 2579–2588. doi:10.1074/jbc.M107894200. PMID 11709551.
- Weinmann AS, Yan PS, Oberley MJ, et al. (2002). "Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis". Genes Dev. 16 (2): 235–244. doi:10.1101/gad.943102. PMC 155318. PMID 11799066.
- Kim HS, Cho JH, Park HW, et al. (2002). "Endotoxin-neutralizing antimicrobial proteins of the human placenta". J. Immunol. 168 (5): 2356–64. doi:10.4049/jimmunol.168.5.2356. PMID 11859126.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Giampuzzi M, Oleggini R, Di Donato A (2003). "Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved". Biochim. Biophys. Acta. 1647 (1–2): 245–51. doi:10.1016/s1570-9639(03)00059-1. PMID 12686141.
- Cheung WL, Ajiro K, Samejima K, et al. (2003). "Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase". Cell. 113 (4): 507–517. doi:10.1016/S0092-8674(03)00355-6. PMID 12757711.
- Tollin M, Bergman P, Svenberg T, et al. (2004). "Antimicrobial peptides in the first line defence of human colon mucosa". Peptides. 24 (4): 523–530. doi:10.1016/S0196-9781(03)00114-1. PMID 12860195.
- Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–811. doi:10.1038/nature02055. PMID 14574404.
- Lusic M, Marcello A, Cereseto A, Giacca M (2004). "Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter". EMBO J. 22 (24): 6550–6561. doi:10.1093/emboj/cdg631. PMC 291826. PMID 14657027.
- Howell SJ, Wilk D, Yadav SP, Bevins CL (2004). "Antimicrobial polypeptides of the human colonic epithelium". Peptides. 24 (11): 1763–1770. doi:10.1016/j.peptides.2003.07.028. PMID 15019208.
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