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<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''Stathmin-2''' is a [[protein]] that in humans is encoded by the ''STMN2'' [[gene]].<ref name="pmid8622778">{{cite journal | vauthors = Okazaki T, Wang H, Masliah E, Cao M, Johnson SA, Sundsmo M, Saitoh T, Mori N | title = SCG10, a neuron-specific growth-associated protein in Alzheimer's disease | journal = Neurobiology of Aging | volume = 16 | issue = 6 | pages = 883–94 | date = June 1996 | pmid = 8622778 | pmc =  | doi = 10.1016/0197-4580(95)02001-2 }}</ref><ref name="pmid12140291">{{cite journal | vauthors = Liu Z, Chatterjee TK, Fisher RA | title = RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6 | journal = The Journal of Biological Chemistry | volume = 277 | issue = 40 | pages = 37832–9 | date = October 2002 | pmid = 12140291 | pmc = | doi = 10.1074/jbc.M205908200 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: STMN2 stathmin-like 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11075| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = no
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Stathmin-like 2
| HGNCid = 10577
| Symbol = STMN2
| AltSymbols =; SCG10; SCGN10; SGC10
| OMIM = 600621
| ECnumber = 
| Homologene = 5102
| MGIid = 98241
| GeneAtlas_image1 = PBB_GE_STMN2_203001_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_STMN2_203000_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005625 |text = soluble fraction}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0030426 |text = growth cone}}
| Process = {{GNF_GO|id=GO:0007242 |text = intracellular signaling cascade}} {{GNF_GO|id=GO:0030182 |text = neuron differentiation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 11075
    | Hs_Ensembl = ENSG00000104435
    | Hs_RefseqProtein = NP_008960
    | Hs_RefseqmRNA = NM_007029
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 8
    | Hs_GenLoc_start = 80711591
    | Hs_GenLoc_end = 80740931
    | Hs_Uniprot = Q93045
    | Mm_EntrezGene = 20257
    | Mm_Ensembl = ENSMUSG00000027500
    | Mm_RefseqmRNA = NM_025285
    | Mm_RefseqProtein = NP_079561
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 3
    | Mm_GenLoc_start = 8492600
    | Mm_GenLoc_end = 8544677
    | Mm_Uniprot = Q545S4
  }}
}}
'''Stathmin-like 2''', also known as '''STMN2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: STMN2 stathmin-like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11075| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Superior cervical [[ganglion]]-10 is a [[neuronal]] growth-associated protein which shares significant [[amino acid]] sequence similarity with the phosphoprotein stathmin (MIM 151442).[supplied by OMIM]<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = Superior cervical [[ganglion]]-10 is a [[neuronal]] growth-associated protein which shares significant [[amino acid]] sequence similarity with the phosphoprotein stathmin (MIM 151442).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: STMN2 stathmin-like 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11075| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
STMN2 has been shown to [[Protein-protein interaction|interact]] with [[RGS6]].<ref name=pmid12140291 />
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Di Paolo G, Lutjens R, Pellier V, Stimpson SA, Beuchat MH, Catsicas S, Grenningloh G | title = Targeting of SCG10 to the area of the Golgi complex is mediated by its NH2-terminal region | journal = The Journal of Biological Chemistry | volume = 272 | issue = 8 | pages = 5175–82 | date = February 1997 | pmid = 9030585 | doi = 10.1074/jbc.272.8.5175 }}
| citations =
* {{cite journal | vauthors = Antonsson B, Lütjens R, Di Paolo G, Kassel D, Allet B, Bernard A, Catsicas S, Grenningloh G | title = Purification, characterization, and in vitro phosphorylation of the neuron-specific membrane-associated protein SCG10 | journal = Protein Expression and Purification | volume = 9 | issue = 3 | pages = 363–71 | date = April 1997 | pmid = 9126608 | doi = 10.1006/prep.1996.0710 }}
*{{cite journal  | author=Okazaki T, Wang H, Masliah E, ''et al.'' |title=SCG10, a neuron-specific growth-associated protein in Alzheimer's disease. |journal=Neurobiol. Aging |volume=16 |issue= 6 |pages= 883-94 |year= 1996 |pmid= 8622778 |doi=  }}
* {{cite journal | vauthors = Antonsson B, Kassel DB, Di Paolo G, Lutjens R, Riederer BM, Grenningloh G | title = Identification of in vitro phosphorylation sites in the growth cone protein SCG10. Effect Of phosphorylation site mutants on microtubule-destabilizing activity | journal = The Journal of Biological Chemistry | volume = 273 | issue = 14 | pages = 8439–46 | date = April 1998 | pmid = 9525956 | doi = 10.1074/jbc.273.14.8439 }}
*{{cite journal | author=Di Paolo G, Lutjens R, Pellier V, ''et al.'' |title=Targeting of SCG10 to the area of the Golgi complex is mediated by its NH2-terminal region. |journal=J. Biol. Chem. |volume=272 |issue= 8 |pages= 5175-82 |year= 1997 |pmid= 9030585 |doi= }}
* {{cite journal | vauthors = Lutjens R, Igarashi M, Pellier V, Blasey H, Di Paolo G, Ruchti E, Pfulg C, Staple JK, Catsicas S, Grenningloh G | title = Localization and targeting of SCG10 to the trans-Golgi apparatus and growth cone vesicles | journal = The European Journal of Neuroscience | volume = 12 | issue = 7 | pages = 2224–34 | date = July 2000 | pmid = 10947801 | doi = 10.1046/j.1460-9568.2000.00112.x }}
*{{cite journal | author=Antonsson B, Lütjens R, Di Paolo G, ''et al.'' |title=Purification, characterization, and in vitro phosphorylation of the neuron-specific membrane-associated protein SCG10. |journal=Protein Expr. Purif. |volume=9 |issue= 3 |pages= 363-71 |year= 1997 |pmid= 9126608 |doi= 10.1006/prep.1996.0710 }}
* {{cite journal | vauthors = Neidhart S, Antonsson B, Gilliéron C, Vilbois F, Grenningloh G, Arkinstall S | title = c-Jun N-terminal kinase-3 (JNK3)/stress-activated protein kinase-beta (SAPKbeta) binds and phosphorylates the neuronal microtubule regulator SCG10 | journal = FEBS Letters | volume = 508 | issue = 2 | pages = 259–64 | date = November 2001 | pmid = 11718727 | doi = 10.1016/S0014-5793(01)03090-3 }}
*{{cite journal | author=Antonsson B, Kassel DB, Di Paolo G, ''et al.'' |title=Identification of in vitro phosphorylation sites in the growth cone protein SCG10. Effect Of phosphorylation site mutants on microtubule-destabilizing activity. |journal=J. Biol. Chem. |volume=273 |issue= 14 |pages= 8439-46 |year= 1998 |pmid= 9525956 |doi= }}
* {{cite journal | vauthors = Nixon AB, Grenningloh G, Casey PJ | title = The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly | journal = The Journal of Biological Chemistry | volume = 277 | issue = 20 | pages = 18127–33 | date = May 2002 | pmid = 11882662 | doi = 10.1074/jbc.M201065200 }}
*{{cite journal | author=Lutjens R, Igarashi M, Pellier V, ''et al.'' |title=Localization and targeting of SCG10 to the trans-Golgi apparatus and growth cone vesicles. |journal=Eur. J. Neurosci. |volume=12 |issue= 7 |pages= 2224-34 |year= 2000 |pmid= 10947801 |doi= }}
* {{cite journal | vauthors = Greka A, Navarro B, Oancea E, Duggan A, Clapham DE | title = TRPC5 is a regulator of hippocampal neurite length and growth cone morphology | journal = Nature Neuroscience | volume = 6 | issue = 8 | pages = 837–45 | date = August 2003 | pmid = 12858178 | doi = 10.1038/nn1092 }}
*{{cite journal | author=Neidhart S, Antonsson B, Gilliéron C, ''et al.'' |title=c-Jun N-terminal kinase-3 (JNK3)/stress-activated protein kinase-beta (SAPKbeta) binds and phosphorylates the neuronal microtubule regulator SCG10. |journal=FEBS Lett. |volume=508 |issue= 2 |pages= 259-64 |year= 2001 |pmid= 11718727 |doi= }}
* {{cite journal | vauthors = Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH | title = A small modulatory dsRNA specifies the fate of adult neural stem cells | journal = Cell | volume = 116 | issue = 6 | pages = 779–93 | date = March 2004 | pmid = 15035981 | doi = 10.1016/S0092-8674(04)00248-X }}
*{{cite journal | author=Nixon AB, Grenningloh G, Casey PJ |title=The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly. |journal=J. Biol. Chem. |volume=277 |issue= 20 |pages= 18127-33 |year= 2002 |pmid= 11882662 |doi= 10.1074/jbc.M201065200 }}
* {{cite journal | vauthors = Gocke CB, Yu H, Kang J | title = Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates | journal = The Journal of Biological Chemistry | volume = 280 | issue = 6 | pages = 5004–12 | date = February 2005 | pmid = 15561718 | doi = 10.1074/jbc.M411718200 }}
*{{cite journal | author=Liu Z, Chatterjee TK, Fisher RA |title=RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6. |journal=J. Biol. Chem. |volume=277 |issue= 40 |pages= 37832-9 |year= 2002 |pmid= 12140291 |doi= 10.1074/jbc.M205908200 }}
* {{cite journal | vauthors = Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE | title = A human protein-protein interaction network: a resource for annotating the proteome | journal = Cell | volume = 122 | issue = 6 | pages = 957–68 | date = September 2005 | pmid = 16169070 | doi = 10.1016/j.cell.2005.08.029 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal  | author=Greka A, Navarro B, Oancea E, ''et al.'' |title=TRPC5 is a regulator of hippocampal neurite length and growth cone morphology. |journal=Nat. Neurosci. |volume=6 |issue= 8 |pages= 837-45 |year= 2003 |pmid= 12858178 |doi= 10.1038/nn1092 }}
* {{cite journal | vauthors = Lee HS, Lee DC, Park MH, Yang SJ, Lee JJ, Kim DM, Jang Y, Lee JH, Choi JY, Kang YK, Kim DI, Park KC, Kim SY, Yoo HS, Choi EJ, Yeom YI | title = STMN2 is a novel target of beta-catenin/TCF-mediated transcription in human hepatoma cells | journal = Biochemical and Biophysical Research Communications | volume = 345 | issue = 3 | pages = 1059–67 | date = July 2006 | pmid = 16712787 | doi = 10.1016/j.bbrc.2006.05.017 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal | vauthors = Manna T, Grenningloh G, Miller HP, Wilson L | title = Stathmin family protein SCG10 differentially regulates the plus and minus end dynamics of microtubules at steady state in vitro: implications for its role in neurite outgrowth | journal = Biochemistry | volume = 46 | issue = 11 | pages = 3543–52 | date = March 2007 | pmid = 17311410 | doi = 10.1021/bi061819d }}
*{{cite journal  | author=Kuwabara T, Hsieh J, Nakashima K, ''et al.'' |title=A small modulatory dsRNA specifies the fate of adult neural stem cells. |journal=Cell |volume=116 |issue= 6 |pages= 779-93 |year= 2004 |pmid= 15035981 |doi= }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Gocke CB, Yu H, Kang J |title=Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates. |journal=J. Biol. Chem. |volume=280 |issue= 6 |pages= 5004-12 |year= 2005 |pmid= 15561718 |doi= 10.1074/jbc.M411718200 }}
*{{cite journal | author=Stelzl U, Worm U, Lalowski M, ''et al.'' |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957-68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Lee HS, Lee DC, Park MH, ''et al.'' |title=STMN2 is a novel target of beta-catenin/TCF-mediated transcription in human hepatoma cells. |journal=Biochem. Biophys. Res. Commun. |volume=345 |issue= 3 |pages= 1059-67 |year= 2006 |pmid= 16712787 |doi= 10.1016/j.bbrc.2006.05.017 }}
*{{cite journal | author=Manna T, Grenningloh G, Miller HP, Wilson L |title=Stathmin family protein SCG10 differentially regulates the plus and minus end dynamics of microtubules at steady state in vitro: implications for its role in neurite outgrowth. |journal=Biochemistry |volume=46 |issue= 11 |pages= 3543-52 |year= 2007 |pmid= 17311410 |doi= 10.1021/bi061819d }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{gene-8-stub}}
{{WikiDoc Sources}}

Latest revision as of 02:11, 27 October 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Stathmin-2 is a protein that in humans is encoded by the STMN2 gene.[1][2][3]

Function

Superior cervical ganglion-10 is a neuronal growth-associated protein which shares significant amino acid sequence similarity with the phosphoprotein stathmin (MIM 151442).[supplied by OMIM][3]

Interactions

STMN2 has been shown to interact with RGS6.[2]

References

  1. Okazaki T, Wang H, Masliah E, Cao M, Johnson SA, Sundsmo M, Saitoh T, Mori N (June 1996). "SCG10, a neuron-specific growth-associated protein in Alzheimer's disease". Neurobiology of Aging. 16 (6): 883–94. doi:10.1016/0197-4580(95)02001-2. PMID 8622778.
  2. 2.0 2.1 Liu Z, Chatterjee TK, Fisher RA (October 2002). "RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6". The Journal of Biological Chemistry. 277 (40): 37832–9. doi:10.1074/jbc.M205908200. PMID 12140291.
  3. 3.0 3.1 "Entrez Gene: STMN2 stathmin-like 2".

Further reading

  • Di Paolo G, Lutjens R, Pellier V, Stimpson SA, Beuchat MH, Catsicas S, Grenningloh G (February 1997). "Targeting of SCG10 to the area of the Golgi complex is mediated by its NH2-terminal region". The Journal of Biological Chemistry. 272 (8): 5175–82. doi:10.1074/jbc.272.8.5175. PMID 9030585.
  • Antonsson B, Lütjens R, Di Paolo G, Kassel D, Allet B, Bernard A, Catsicas S, Grenningloh G (April 1997). "Purification, characterization, and in vitro phosphorylation of the neuron-specific membrane-associated protein SCG10". Protein Expression and Purification. 9 (3): 363–71. doi:10.1006/prep.1996.0710. PMID 9126608.
  • Antonsson B, Kassel DB, Di Paolo G, Lutjens R, Riederer BM, Grenningloh G (April 1998). "Identification of in vitro phosphorylation sites in the growth cone protein SCG10. Effect Of phosphorylation site mutants on microtubule-destabilizing activity". The Journal of Biological Chemistry. 273 (14): 8439–46. doi:10.1074/jbc.273.14.8439. PMID 9525956.
  • Lutjens R, Igarashi M, Pellier V, Blasey H, Di Paolo G, Ruchti E, Pfulg C, Staple JK, Catsicas S, Grenningloh G (July 2000). "Localization and targeting of SCG10 to the trans-Golgi apparatus and growth cone vesicles". The European Journal of Neuroscience. 12 (7): 2224–34. doi:10.1046/j.1460-9568.2000.00112.x. PMID 10947801.
  • Neidhart S, Antonsson B, Gilliéron C, Vilbois F, Grenningloh G, Arkinstall S (November 2001). "c-Jun N-terminal kinase-3 (JNK3)/stress-activated protein kinase-beta (SAPKbeta) binds and phosphorylates the neuronal microtubule regulator SCG10". FEBS Letters. 508 (2): 259–64. doi:10.1016/S0014-5793(01)03090-3. PMID 11718727.
  • Nixon AB, Grenningloh G, Casey PJ (May 2002). "The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly". The Journal of Biological Chemistry. 277 (20): 18127–33. doi:10.1074/jbc.M201065200. PMID 11882662.
  • Greka A, Navarro B, Oancea E, Duggan A, Clapham DE (August 2003). "TRPC5 is a regulator of hippocampal neurite length and growth cone morphology". Nature Neuroscience. 6 (8): 837–45. doi:10.1038/nn1092. PMID 12858178.
  • Kuwabara T, Hsieh J, Nakashima K, Taira K, Gage FH (March 2004). "A small modulatory dsRNA specifies the fate of adult neural stem cells". Cell. 116 (6): 779–93. doi:10.1016/S0092-8674(04)00248-X. PMID 15035981.
  • Gocke CB, Yu H, Kang J (February 2005). "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates". The Journal of Biological Chemistry. 280 (6): 5004–12. doi:10.1074/jbc.M411718200. PMID 15561718.
  • Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (September 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
  • Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Lee HS, Lee DC, Park MH, Yang SJ, Lee JJ, Kim DM, Jang Y, Lee JH, Choi JY, Kang YK, Kim DI, Park KC, Kim SY, Yoo HS, Choi EJ, Yeom YI (July 2006). "STMN2 is a novel target of beta-catenin/TCF-mediated transcription in human hepatoma cells". Biochemical and Biophysical Research Communications. 345 (3): 1059–67. doi:10.1016/j.bbrc.2006.05.017. PMID 16712787.
  • Manna T, Grenningloh G, Miller HP, Wilson L (March 2007). "Stathmin family protein SCG10 differentially regulates the plus and minus end dynamics of microtubules at steady state in vitro: implications for its role in neurite outgrowth". Biochemistry. 46 (11): 3543–52. doi:10.1021/bi061819d. PMID 17311410.