IFNA17: Difference between revisions

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{{Infobox_gene}}
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'''Interferon alpha-17''' is a [[protein]] that in humans is encoded by the ''IFNA17'' [[gene]].<ref name="pmid1385305">{{cite journal |vauthors=Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO | title = Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia | journal = Genomics | volume = 14 | issue = 2 | pages = 437–43 |date=Dec 1992 | pmid = 1385305 | pmc =  | doi =10.1016/S0888-7543(05)80238-1 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IFNA17 interferon, alpha 17| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3451| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source = 
| PDB =
| Name = Interferon, alpha 17
| HGNCid = 5422
| Symbol = IFNA17
| AltSymbols =; IFNA
| OMIM = 147583
| ECnumber =
| Homologene = 86769
| MGIid = 3649260
| GeneAtlas_image1 = PBB_GE_IFNA17_207964_x_at_tn.png
  | GeneAtlas_image2 = PBB_GE_IFNA17_208259_x_at_tn.png
| GeneAtlas_image3 = PBB_GE_IFNA17_208261_x_at_tn.png
| Function = {{GNF_GO|id=GO:0005132 |text = interferon-alpha/beta receptor binding}}
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}}
| Process = {{GNF_GO|id=GO:0006952 |text = defense response}} {{GNF_GO|id=GO:0007267 |text = cell-cell signaling}} {{GNF_GO|id=GO:0009615 |text = response to virus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3451
    | Hs_Ensembl = ENSG00000186809
    | Hs_RefseqProtein = NP_067091
    | Hs_RefseqmRNA = NM_021268
    | Hs_GenLoc_db =  
    | Hs_GenLoc_chr = 9
    | Hs_GenLoc_start = 21217242
    | Hs_GenLoc_end = 21218221
    | Hs_Uniprot = P01571
    | Mm_EntrezGene = 230398
    | Mm_Ensembl = ENSMUSG00000063916
    | Mm_RefseqmRNA = NM_206867
    | Mm_RefseqProtein = NP_996750
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 88147518
    | Mm_GenLoc_end = 88148087
    | Mm_Uniprot = 
  }}
}}
'''Interferon, alpha 17''', also known as '''IFNA17''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: IFNA17 interferon, alpha 17| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3451| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Sen GC, Lengyel P |title=The interferon system. A bird's eye view of its biochemistry. |journal=J. Biol. Chem. |volume=267 |issue= 8 |pages= 5017-20 |year= 1992 |pmid= 1371992 |doi=  }}
*{{cite journal  |vauthors=Sen GC, Lengyel P |title=The interferon system. A bird's eye view of its biochemistry. |journal=J. Biol. Chem. |volume=267 |issue= 8 |pages= 5017–20 |year= 1992 |pmid= 1371992 |doi=  }}
*{{cite journal | author=Olopade OI, Bohlander SK, Pomykala H, ''et al.'' |title=Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. |journal=Genomics |volume=14 |issue= 2 |pages= 437-43 |year= 1992 |pmid= 1385305 |doi=  }}
*{{cite journal   |vauthors=Zoon KC, Miller D, Bekisz J, etal |title=Purification and characterization of multiple components of human lymphoblastoid interferon-alpha. |journal=J. Biol. Chem. |volume=267 |issue= 21 |pages= 15210–6 |year= 1992 |pmid= 1634550 |doi=  }}
*{{cite journal  | author=Zoon KC, Miller D, Bekisz J, ''et al.'' |title=Purification and characterization of multiple components of human lymphoblastoid interferon-alpha. |journal=J. Biol. Chem. |volume=267 |issue= 21 |pages= 15210-6 |year= 1992 |pmid= 1634550 |doi=  }}
*{{cite journal   |vauthors=Savel'ev VI, Zlochevskiĭ ML, Sorokin AV, etal |title=[Cloning and the determination of the nucleotide sequences in 2 genes of human leukocyte interferons] |journal=Antibiot. Med. Biotekhnol. |volume=31 |issue= 8 |pages= 592–6 |year= 1986 |pmid= 3767336 |doi=  }}
*{{cite journal | author=Savel'ev VI, Zlochevskiĭ ML, Sorokin AV, ''et al.'' |title=[Cloning and the determination of the nucleotide sequences in 2 genes of human leukocyte interferons] |journal=Antibiot. Med. Biotekhnol. |volume=31 |issue= 8 |pages= 592-6 |year= 1986 |pmid= 3767336 |doi=  }}
*{{cite journal  |vauthors=Mizoguchi J, Pitha PM, Raj NB |title=Efficient expression in Escherichia coli of two species of human interferon-alpha and their hybrid molecules. |journal=DNA |volume=4 |issue= 3 |pages= 221–32 |year= 1985 |pmid= 3891272 |doi=10.1089/dna.1985.4.221 }}
*{{cite journal  | author=Mizoguchi J, Pitha PM, Raj NB |title=Efficient expression in Escherichia coli of two species of human interferon-alpha and their hybrid molecules. |journal=DNA |volume=4 |issue= 3 |pages= 221-32 |year= 1985 |pmid= 3891272 |doi=  }}
*{{cite journal   |vauthors=Lund B, von Gabain A, Edlund T, etal |title=Differential expression of interferon genes in a substrain of Namalwa cells. |journal=J. Interferon Res. |volume=5 |issue= 2 |pages= 229–38 |year= 1985 |pmid= 4008999 |doi=  10.1089/jir.1985.5.229}}
*{{cite journal | author=Lund B, von Gabain A, Edlund T, ''et al.'' |title=Differential expression of interferon genes in a substrain of Namalwa cells. |journal=J. Interferon Res. |volume=5 |issue= 2 |pages= 229-38 |year= 1985 |pmid= 4008999 |doi=  }}
*{{cite journal   |vauthors=Lawn RM, Adelman J, Dull TJ, etal |title=DNA sequence of two closely linked human leukocyte interferon genes. |journal=Science |volume=212 |issue= 4499 |pages= 1159–62 |year= 1981 |pmid= 6165082 |doi=10.1126/science.6165082 }}
*{{cite journal | author=Lawn RM, Adelman J, Dull TJ, ''et al.'' |title=DNA sequence of two closely linked human leukocyte interferon genes. |journal=Science |volume=212 |issue= 4499 |pages= 1159-62 |year= 1981 |pmid= 6165082 |doi=  }}
*{{cite journal  |vauthors=Fuke M, Hendrix LC, Bollon AP |title=Pseudogene IFN-alpha L: removal of the stop codon in the signal sequence permits expression of active human interferon. |journal=Gene |volume=32 |issue= 1-2 |pages= 135–40 |year= 1985 |pmid= 6397400 |doi=10.1016/0378-1119(84)90041-6 }}
*{{cite journal  | author=Fuke M, Hendrix LC, Bollon AP |title=Pseudogene IFN-alpha L: removal of the stop codon in the signal sequence permits expression of active human interferon. |journal=Gene |volume=32 |issue= 1-2 |pages= 135-40 |year= 1985 |pmid= 6397400 |doi=  }}
*{{cite journal   |vauthors=Tiefenbrun N, Melamed D, Levy N, etal |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934–44 |year= 1996 |pmid= 8668211 |doi= | pmc=231390 }}
*{{cite journal | author=Tiefenbrun N, Melamed D, Levy N, ''et al.'' |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934-44 |year= 1996 |pmid= 8668211 |doi=  }}
*{{cite journal  |vauthors=Nyman TA, Tölö H, Parkkinen J, Kalkkinen N |title=Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes. |journal=Biochem. J. |volume=329 |issue=  2|pages= 295–302 |year= 1998 |pmid= 9425112 |doi= | pmc=1219044 }}
*{{cite journal  | author=Nyman TA, Tölö H, Parkkinen J, Kalkkinen N |title=Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes. |journal=Biochem. J. |volume=329 ( Pt 2) |issue=  |pages= 295-302 |year= 1998 |pmid= 9425112 |doi=  }}
*{{cite journal   |vauthors=Hussain M, Tan T, Ni D, etal |title=A new allele of interferon-alpha17 gene encoding IFN-alpha17b is the major variant in human population. |journal=J. Interferon Cytokine Res. |volume=18 |issue= 7 |pages= 469–77 |year= 1998 |pmid= 9712362 |doi=10.1089/jir.1998.18.469 }}
*{{cite journal | author=Hussain M, Tan T, Ni D, ''et al.'' |title=A new allele of interferon-alpha17 gene encoding IFN-alpha17b is the major variant in human population. |journal=J. Interferon Cytokine Res. |volume=18 |issue= 7 |pages= 469-77 |year= 1998 |pmid= 9712362 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Kim JW, Roh JW, Park NH, etal |title=Interferon, alpha 17 (IFNA17) Ile184Arg polymorphism and cervical cancer risk. |journal=Cancer Lett. |volume=189 |issue= 2 |pages= 183–8 |year= 2003 |pmid= 12490311 |doi=10.1016/S0304-3835(02)00548-7 }}
*{{cite journal | author=Kim JW, Roh JW, Park NH, ''et al.'' |title=Interferon, alpha 17 (IFNA17) Ile184Arg polymorphism and cervical cancer risk. |journal=Cancer Lett. |volume=189 |issue= 2 |pages= 183-8 |year= 2003 |pmid= 12490311 |doi=  }}
}}
}}
{{refend}}
{{refend}}


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{{Cytokine receptor modulators}}
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{{gene-9-stub}}

Latest revision as of 23:39, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Interferon alpha-17 is a protein that in humans is encoded by the IFNA17 gene.[1][2]


References

  1. Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (Dec 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.
  2. "Entrez Gene: IFNA17 interferon, alpha 17".

Further reading