Non-alcoholic fatty liver disease MRI: Difference between revisions
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==Overview== | ==Overview== | ||
Abdominal MRI may be helpful in the diagnosis of non-alcoholic fatty liver disease. Findings on MRI suggestive of non-alcoholic fatty liver disease include [[quantification]] of the [[hepatic steatosis]]. MRI has a [[Sensitivity (tests)|sensitivity]] of 96% and [[specificity]] of 93% in diagnosing NAFLD. However, it uses is limited because of the cost. | |||
MRI | |||
==MRI== | ==MRI== | ||
*Abdominal MRI may be helpful in the diagnosis of NAFLD. | *[[Abdominal]] [[MRI]] may be helpful in the diagnosis of NAFLD.<ref name="urlNonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician">{{cite web |url=http://www.aafp.org/afp/2013/0701/p35.html#afp20130701p35-b13 |title=Nonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician |format= |work= |accessdate=}}</ref><ref name="urlNonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician2">{{cite web |url=http://www.aafp.org/afp/2013/0701/p35.html |title=Nonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician |format= |work= |accessdate=}}</ref> | ||
*MRI | *Findings on [[MRI]] suggestive NAFLD include: | ||
**Quantification of hepatic steatosis.<ref name="pmid24040614">{{cite journal |vauthors=Ligabue G, Besutti G, Scaglioni R, Stentarelli C, Guaraldi G |title=MR quantitative biomarkers of non-alcoholic fatty liver disease: technical evolutions and future trends |journal=Quant Imaging Med Surg |volume=3 |issue=4 |pages=192–5 |year=2013 |pmid=24040614 |pmc=3759141 |doi=10.3978/j.issn.2223-4292.2013.08.01 |url=}}</ref> | **[[Quantification]] of [[hepatic steatosis]].<ref name="pmid24040614">{{cite journal |vauthors=Ligabue G, Besutti G, Scaglioni R, Stentarelli C, Guaraldi G |title=MR quantitative biomarkers of non-alcoholic fatty liver disease: technical evolutions and future trends |journal=Quant Imaging Med Surg |volume=3 |issue=4 |pages=192–5 |year=2013 |pmid=24040614 |pmc=3759141 |doi=10.3978/j.issn.2223-4292.2013.08.01 |url=}}</ref><ref name="pmid24966609">{{cite journal |vauthors=Lee SS, Park SH |title=Radiologic evaluation of nonalcoholic fatty liver disease |journal=World J. Gastroenterol. |volume=20 |issue=23 |pages=7392–402 |year=2014 |pmid=24966609 |pmc=4064084 |doi=10.3748/wjg.v20.i23.7392 |url=}}</ref> | ||
**Drop in signal intensity in liver on the out-of-phase sequence, compatible with intra-cellular lipid deposition. | |||
*Another kind of MRI is magnetic resonance spectroscopy (MRS) which reflects | *MRI also helps longitudinal follow-up of patients with non-alcoholic fatty liver disease to check response to therapy | ||
*Another kind of MRI is magnetic resonance spectroscopy (MRS) which reflects fat in the whole liver like [[Triglyceride|triglycerides]] in a specific volume; and [[proton]] density fat fraction (PDFF).<ref name="pmid288000872">{{cite journal |vauthors=Di Martino M, Koryukova K, Bezzi M, Catalano C |title=Imaging Features of Non-Alcoholic Fatty Liver Disease in Children and Adolescents |journal=Children (Basel) |volume=4 |issue=8 |pages= |year=2017 |pmid=28800087 |pmc=5575595 |doi=10.3390/children4080073 |url=}}</ref> | |||
==References== | ==References== | ||
Latest revision as of 20:17, 22 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Abdominal MRI may be helpful in the diagnosis of non-alcoholic fatty liver disease. Findings on MRI suggestive of non-alcoholic fatty liver disease include quantification of the hepatic steatosis. MRI has a sensitivity of 96% and specificity of 93% in diagnosing NAFLD. However, it uses is limited because of the cost.
MRI
- Abdominal MRI may be helpful in the diagnosis of NAFLD.[1][2]
- Findings on MRI suggestive NAFLD include:
- Quantification of hepatic steatosis.[3][4]
- Drop in signal intensity in liver on the out-of-phase sequence, compatible with intra-cellular lipid deposition.
- MRI also helps longitudinal follow-up of patients with non-alcoholic fatty liver disease to check response to therapy
- Another kind of MRI is magnetic resonance spectroscopy (MRS) which reflects fat in the whole liver like triglycerides in a specific volume; and proton density fat fraction (PDFF).[5]
References
- ↑ "Nonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician".
- ↑ "Nonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician".
- ↑ Ligabue G, Besutti G, Scaglioni R, Stentarelli C, Guaraldi G (2013). "MR quantitative biomarkers of non-alcoholic fatty liver disease: technical evolutions and future trends". Quant Imaging Med Surg. 3 (4): 192–5. doi:10.3978/j.issn.2223-4292.2013.08.01. PMC 3759141. PMID 24040614.
- ↑ Lee SS, Park SH (2014). "Radiologic evaluation of nonalcoholic fatty liver disease". World J. Gastroenterol. 20 (23): 7392–402. doi:10.3748/wjg.v20.i23.7392. PMC 4064084. PMID 24966609.
- ↑ Di Martino M, Koryukova K, Bezzi M, Catalano C (2017). "Imaging Features of Non-Alcoholic Fatty Liver Disease in Children and Adolescents". Children (Basel). 4 (8). doi:10.3390/children4080073. PMC 5575595. PMID 28800087.