Thalassemia risk factors: Difference between revisions
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==Overview== | |||
The risks factors for thalassemia include birth to parents of Mediterranean or Southeast Asian descent. There are some other geographic areas that have a high prevalence of thalassemia such that ancestry from these areas constitute a risk factor for development of thalassemia. Since this is a monogenic disorder, there are no other particular risk factors. Environmental factors do not play a role in development of thalassemia. | |||
==Risk Factors== | |||
*'''Ethnicity:''' Patients at high risk include persons of Mediterranean countries, Southeast Asia, Indian subcontinent, and the Middle East.<ref name="pmid20665635">{{cite journal| author=Roselli EA, Mezzadra R, Frittoli MC, Maruggi G, Biral E, Mavilio F et al.| title=Correction of beta-thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients. | journal=EMBO Mol Med | year= 2010 | volume= 2 | issue= 8 | pages= 315-28 | pmid=20665635 | doi=10.1002/emmm.201000083 | pmc=3377331 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20665635 }} </ref> | |||
*'''Gender:''' There is no gender predilection for thalassemia. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Hematology]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Latest revision as of 15:47, 26 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2]
Overview
The risks factors for thalassemia include birth to parents of Mediterranean or Southeast Asian descent. There are some other geographic areas that have a high prevalence of thalassemia such that ancestry from these areas constitute a risk factor for development of thalassemia. Since this is a monogenic disorder, there are no other particular risk factors. Environmental factors do not play a role in development of thalassemia.
Risk Factors
- Ethnicity: Patients at high risk include persons of Mediterranean countries, Southeast Asia, Indian subcontinent, and the Middle East.[1]
- Gender: There is no gender predilection for thalassemia.
References
- ↑ Roselli EA, Mezzadra R, Frittoli MC, Maruggi G, Biral E, Mavilio F; et al. (2010). "Correction of beta-thalassemia major by gene transfer in haematopoietic progenitors of pediatric patients". EMBO Mol Med. 2 (8): 315–28. doi:10.1002/emmm.201000083. PMC 3377331. PMID 20665635.