Linitis plastica history and symptoms: Difference between revisions

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{{Linitis plastica}}
{{Linitis plastica}}
{{CMG}}{{AE}} {{STM}}
{{CMG}}; {{AE}}{{HM}}


==Overview==
==Overview==
Symptoms of linitis plastica may include [[dyspepsia]], nausea, vomiting, early satiety, loss of [[appetite]], weight loss, abdominal discomfort and sometimes [[diarrhea]].<ref name=gh>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.</ref><ref name=wi>Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015</ref> <ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032  }} </ref> A positive family history of diffuse gastric cancer may be present if it is the hereditary form of the disease.
Symptoms of linitis plastica may include [[dyspepsia]], nausea, vomiting, early satiety, loss of [[appetite]], weight loss, abdominal pain/discomfort and sometimes [[diarrhea]]. A positive family history of diffuse gastric cancer may be present if it is the hereditary form of the disease.


==History and symptoms==
==History==
*Diffuse gastric [[adenocarcinoma]] or linitis plastica remains asymptomatic for a long time before diagnosis. Therefore, when a patient presents with symptoms, the disease is usually in an advanced stage.<ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032  }} </ref>
*A family history of linitis plastica may be present in patients with hereditary diffuse [[adenocarcinoma]].<ref name="pmid8239772">{{cite journal |vauthors=Wanebo HJ, Kennedy BJ, Chmiel J, Steele G, Winchester D, Osteen R |title=Cancer of the stomach. A patient care study by the American College of Surgeons |journal=Ann. Surg. |volume=218 |issue=5 |pages=583–92 |year=1993 |pmid=8239772 |pmc=1243028 |doi= |url=}}</ref><ref name="pmid2793233">{{cite journal |vauthors=Buiatti E, Palli D, Decarli A, Amadori D, Avellini C, Bianchi S, Biserni R, Cipriani F, Cocco P, Giacosa A |title=A case-control study of gastric cancer and diet in Italy |journal=Int. J. Cancer |volume=44 |issue=4 |pages=611–6 |year=1989 |pmid=2793233 |doi= |url=}}</ref>
*Thickening and rigidity of the stomach wall makes the process of digestion difficult and the patient may complain of nausea, vomiting, [[bloating]] and sometimes diarrhea.
 
*Patients may develop non specific symptoms like:<ref name=gh>Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273. Accessed on December 8, 2015.</ref><ref name=wi>Linitis plastica. Wikipedia. https://en.wikipedia.org/wiki/Linitis_plastica Accessed on December 8, 2015</ref><ref name="pmid23984032">{{cite journal| author=Jafferbhoy S, Shiwani H, Rustum Q| title=Managing Gastric Linitis Plastica: Keep the scalpel sheathed. | journal=Sultan Qaboos Univ Med J | year= 2013 | volume= 13 | issue= 3 | pages= 451-3 | pmid=23984032 | doi= | pmc=PMC3749031 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23984032  }} </ref>
==Symptoms==
*Thickening and rigidity of the stomach wall makes the process of digestion difficult and the patient may complain of:<ref name="pmid2793233">{{cite journal |vauthors=Buiatti E, Palli D, Decarli A, Amadori D, Avellini C, Bianchi S, Biserni R, Cipriani F, Cocco P, Giacosa A |title=A case-control study of gastric cancer and diet in Italy |journal=Int. J. Cancer |volume=44 |issue=4 |pages=611–6 |year=1989 |pmid=2793233 |doi= |url=}}</ref><ref name="pmid8239772">{{cite journal |vauthors=Wanebo HJ, Kennedy BJ, Chmiel J, Steele G, Winchester D, Osteen R |title=Cancer of the stomach. A patient care study by the American College of Surgeons |journal=Ann. Surg. |volume=218 |issue=5 |pages=583–92 |year=1993 |pmid=8239772 |pmc=1243028 |doi= |url=}}</ref>
**[[Vomiting]]
**[[Bloating]]
**[[Diarrhea]]
*Patients may develop non specific symptoms such as:
**[[Dyspepsia]]
**[[Dyspepsia]]
**[[Dysphagia]]
**[[Dysphagia]]
**Early satiety
**Early satiety
**[[Anorexia]]
**Weight loss
**Weight loss
**Loss of [[appetite]]
**Abdominal discomfort and/or pain
**Abdominal discomfort
*A family history of linitis plastica may be present in patients with the hereditary diffuse [[adenocarcinoma]], which is [[autosomal dominant]]ly inherited.


==References==
==References==

Latest revision as of 19:37, 16 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

Symptoms of linitis plastica may include dyspepsia, nausea, vomiting, early satiety, loss of appetite, weight loss, abdominal pain/discomfort and sometimes diarrhea. A positive family history of diffuse gastric cancer may be present if it is the hereditary form of the disease.

History

  • A family history of linitis plastica may be present in patients with hereditary diffuse adenocarcinoma.[1][2]

Symptoms

  • Thickening and rigidity of the stomach wall makes the process of digestion difficult and the patient may complain of:[2][1]
  • Patients may develop non specific symptoms such as:

References

  1. 1.0 1.1 Wanebo HJ, Kennedy BJ, Chmiel J, Steele G, Winchester D, Osteen R (1993). "Cancer of the stomach. A patient care study by the American College of Surgeons". Ann. Surg. 218 (5): 583–92. PMC 1243028. PMID 8239772.
  2. 2.0 2.1 Buiatti E, Palli D, Decarli A, Amadori D, Avellini C, Bianchi S, Biserni R, Cipriani F, Cocco P, Giacosa A (1989). "A case-control study of gastric cancer and diet in Italy". Int. J. Cancer. 44 (4): 611–6. PMID 2793233.


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