Linitis plastica other diagnostic studies: Difference between revisions
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==Overview== | ==Overview== | ||
Brush cytology may be helpful in the diagnosis of linitis plastica and its complications. Brush cytology has the ability to increase the sensitivity of even a single biopsy carried out by endoscopic ultrasound. If bleeding is a concern in the patient, brush cytology is able to take samples of the mucosa without | Brush cytology may be helpful in the diagnosis of linitis plastica and its complications. Brush cytology has the ability to increase the [[Sensitivity (tests)|sensitivity]] of even a single [[biopsy]] carried out by [[endoscopic ultrasound]]. If bleeding is a concern in the patient, brush cytology is able to take samples of the [[Mucous membrane|mucosa]] without causing bleeds. [[Immunohistochemistry|Immunohistochemical staining]] then confirms the diagnosis of linitis plastica by the detection of [[Signet cell|signet ring cells]]. Peritoneal cytology can also be useful in those that are negative for [[metastasis]] elsewhere. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Brush cytology=== | ===Brush cytology=== | ||
*Brush cytology with immunohistochemical staining may be helpful in the diagnosis of linitis plastica.<ref name="pmid2028694">{{cite journal |vauthors=Wang HH, Jonasson JG, Ducatman BS |title=Brushing cytology of the upper gastrointestinal tract. Obsolete or not? |journal=Acta Cytol. |volume=35 |issue=2 |pages=195–8 |year=1991 |pmid=2028694 |doi= |url=}}</ref> | *Brush cytology with [[Immunohistochemistry|immunohistochemical staining]] may be helpful in the diagnosis of linitis plastica.<ref name="pmid2028694">{{cite journal |vauthors=Wang HH, Jonasson JG, Ducatman BS |title=Brushing cytology of the upper gastrointestinal tract. Obsolete or not? |journal=Acta Cytol. |volume=35 |issue=2 |pages=195–8 |year=1991 |pmid=2028694 |doi= |url=}}</ref> | ||
*Brush cytology has the following advantages: | *Brush cytology has the following advantages: | ||
**No risk of bleeding | **No risk of bleeding | ||
**Increased sensitivity of single biopsy | **Increased [[Sensitivity (tests)|sensitivity]] of single biopsy | ||
**Sensitive to poorly differentiated linits plastica | **Sensitive to poorly differentiated linits plastica | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Latest revision as of 20:08, 16 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Brush cytology may be helpful in the diagnosis of linitis plastica and its complications. Brush cytology has the ability to increase the sensitivity of even a single biopsy carried out by endoscopic ultrasound. If bleeding is a concern in the patient, brush cytology is able to take samples of the mucosa without causing bleeds. Immunohistochemical staining then confirms the diagnosis of linitis plastica by the detection of signet ring cells. Peritoneal cytology can also be useful in those that are negative for metastasis elsewhere.
Other Diagnostic Studies
Brush cytology
- Brush cytology with immunohistochemical staining may be helpful in the diagnosis of linitis plastica.[1]
- Brush cytology has the following advantages:
- No risk of bleeding
- Increased sensitivity of single biopsy
- Sensitive to poorly differentiated linits plastica