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| {{Infobox_Disease |
| | #REDIRECT[[Autoimmune polyendocrine syndrome]] |
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| ==Overview==
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| The '''polyendocrine deficiency syndrome''' is classified into two separate forms, referred to as type I and type II.
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| Type I occurs in children, and [[adrenal insufficiency]] may be accompanied by:
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| * underactive [[parathyroid gland]]s
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| * slow sexual development
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| * [[pernicious anemia]]
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| * chronic [[candida]] infections
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| * [[chronic active hepatitis]]
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| * hair loss (in very rare cases)
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| Type II, often called [[Schmidt's syndrome]], usually afflicts young adults. Features of type II may include:
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| * an underactive [[thyroid gland]]
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| * slow sexual development
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| * [[diabetes mellitus]]
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| * [[vitiligo]]
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| * loss of pigment on areas of the skin
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| Scientists think that the polyendocrine deficiency syndrome is inherited because frequently more than one family member tends to have one or more endocrine deficiencies.
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| ==References==
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| {{Refbegin|2}}
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| * Stewart PM. The adrenal cortex. In: Larsen P, ed. Williams Textbook of Endocrinology. 10th ed. Philadelphia: Saunders; 2003: 491–551.
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| * Chrousos GP. Glucocorticoid therapy. In: Felig P, Frohman L, eds. Endocrinology and Metabolism. 4th ed. New York: McGraw-Hill; 2001: 609–632.
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| * Miller W, Chrousos GP. The adrenal cortex. In: Felig P, Frohman L, eds. Endocrinology and Metabolism. 4th ed. New York: McGraw-Hill; 2001: 387–524.
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| * Ten S, New M, Maclaren N. Clinical Review 130: Addison's disease 2001. Journal of Clinical Endocrinology & Metabolism. 2001;86(7):2909–2922.
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| * Williams GH, Dluhy, RC. Disorders of the adrenal cortex. In: Braunwald E, ed. Harrison's Principles of Internal Medicine. 15th ed. New York: McGraw-Hill Professional; 2001: 2084–2105.
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| {{Refend}}
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| {{Symptoms and signs}}
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| {{SIB}}
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| [[Category:Endocrinology]]
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