Mesothelioma history and symptoms: Difference between revisions

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Latest revision as of 14:35, 19 March 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma. Detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to asbestos or radiation.Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to asbestos. Symptoms of mesothelioma include chest pain nonpleuritic in nature, shortness of breath, cough, fatigue, palpitation, hemoptysis, fever and weight loss.

History

Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma.^[1]^[2]
A detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to asbestos or radiation.

Symptoms

Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to asbestos. Symptoms of mesothelioma include chest pain nonpleuritic in nature, shortness of breath, cough, fatigue, palpitation, hemoptysis, fever and weight loss. As the tumor grows in size, it may present with one or more symptoms. Symptoms of mesothelioma depend on the location of the tumor.^[3]^[4]

Mesothelioma that affects the pleura can cause:

Mesothelioma that affects the peritoneum can cause:

Mesothelioma that affects the pericardium can cause:

References

↑ Risk factors for mesothelioma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/mesothelioma/risks/?region=on. Accessed on February 16, 2016
↑ Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.
↑ Yang H, Testa JR, Carbone M (June 2008). "Mesothelioma epidemiology, carcinogenesis, and pathogenesis". Curr Treat Options Oncol. 9 (2–3): 147–57. doi:10.1007/s11864-008-0067-z. PMC 2717086. PMID 18709470.
↑ Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.

Template:WikiDoc Sources

[Riskfactorsformesothelioma1-1] Risk factors for mesothelioma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/mesothelioma/risks/?region=on. Accessed on February 16, 2016

[pmid29507793-2] Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.

[pmid18709470-3] Yang H, Testa JR, Carbone M (June 2008). "Mesothelioma epidemiology, carcinogenesis, and pathogenesis". Curr Treat Options Oncol. 9 (2–3): 147–57. doi:10.1007/s11864-008-0067-z. PMC 2717086. PMID 18709470.

[pmid295077932-4] Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.

[1]

[2]

[3]

[4]

@@ Line 4: / Line 4: @@
 ==Overview==
+Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma. Detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to [[asbestos]] or [[radiation]].Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to [[asbestos]]. Symptoms of mesothelioma include [[chest pain]] nonpleuritic in nature, [[shortness of breath]], [[cough]], [[fatigue]], [[palpitation]], [[hemoptysis]], [[fever]] and [[weight loss]].
 ==History==
+*Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma.<ref name="Riskfactorsformesothelioma1">Risk factors for mesothelioma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/mesothelioma/risks/?region=on. Accessed on February 16, 2016</ref><ref name="pmid29507793">{{cite journal |vauthors=Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A |title=Clinical diagnosis of malignant pleural mesothelioma |journal=J Thorac Dis |volume=10 |issue=Suppl 2 |pages=S253–S261 |date=January 2018 |pmid=29507793 |pmc=5830561 |doi=10.21037/jtd.2017.10.09 |url=}}</ref>
+*A detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to [[asbestos]] or [[radiation]].
 ==Symptoms==
-Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. Shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space are often symptoms of pleural mesothelioma.
+*Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to [[asbestos]]. Symptoms of mesothelioma include [[chest pain]] nonpleuritic in nature, [[shortness of breath]], [[cough]], [[fatigue]], [[palpitation]], [[hemoptysis]], [[fever]] and [[weight loss]]. As the tumor grows in size, it may present with one or more symptoms. Symptoms of mesothelioma depend on the location of the tumor.<ref name="pmid18709470">{{cite journal |vauthors=Yang H, Testa JR, Carbone M |title=Mesothelioma epidemiology, carcinogenesis, and pathogenesis |journal=Curr Treat Options Oncol |volume=9 |issue=2-3 |pages=147–57 |date=June 2008 |pmid=18709470 |pmc=2717086 |doi=10.1007/s11864-008-0067-z |url=}}</ref><ref name="pmid295077932">{{cite journal |vauthors=Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A |title=Clinical diagnosis of malignant pleural mesothelioma |journal=J Thorac Dis |volume=10 |issue=Suppl 2 |pages=S253–S261 |date=January 2018 |pmid=29507793 |pmc=5830561 |doi=10.21037/jtd.2017.10.09 |url=}}</ref>
-Symptoms of [[peritoneum|peritoneal]] mesothelioma include weight loss and [[cachexia]], abdominal swelling and pain due to [[ascites]] (a buildup of fluid in the abdominal cavity). Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, [[anemia]], and [[fever]]. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.
-These symptoms may be caused by  mesothelioma or by other, less serious conditions.
-Mesothelioma that affects the pleura can cause these signs and symptoms:
+'''Mesothelioma that affects the pleura can cause:'''
-* Chest wall pain
+*[[Chest pain]]
-* Pleural effusion, or fluid surrounding the lung
+*[[Shortness of breath]]
-* Shortness of breath
+*[[Cough]]
-* Fatigue or anemia
+*[[hemoptysis|Blood in sputum]]
-* Wheezing, hoarseness, or cough
+*[[Fever]]
-* Blood in the [[sputum]] (fluid) coughed up
+*[[Sweating]]
+*[[Fatigue]]
+*[[Weight loss]]
+*[[dysphagia|Difficulty in swallowing]]
-In severe cases, the person may have many [[tumor]] masses. The individual may develop a [[pneumothorax]], or collapse of the [[lung]]. The disease may [[metastasize]], or spread, to other parts of the body.
+'''Mesothelioma that affects the peritoneum can cause:'''
+*[[Abdominal pain]]
+*[[Abdominal distension]]
+*[[abdominal mass|Lump in the abdomen]]
+*[[Fatigue]]
+*[[Weight loss]]
-Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. Symptoms include:
+'''Mesothelioma that affects the pericardium can cause:'''
-* Abdominal pain
+*[[Palpitation]]
-* [[Ascites]], or an abnormal buildup of fluid in the abdomen
+*[[Cough]]
-* A mass in the abdomen
+*[[Hemoptysis]]
-* Problems with bowel function
+*[[Dizziness]]
-* Weight loss
+*[[pedal edema|Swelling in legs]]
+*[[Fatigue]]
+*[[Night sweats]]
 ==References==
@@ Line 43: / Line 51: @@
 [[Category:Occupational diseases]]
 [[Category:Oncology]]
+ [[Category:Up-To-Date]]
+[[Category:Oncology]]
+[[Category:Medicine]]