Mesothelioma history and symptoms: Difference between revisions

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==History and Symptoms==
==Overview==
Symptoms of mesothelioma may not appear until 20 to 50 years after exposure to asbestos. Shortness of breath, cough, and pain in the chest due to an accumulation of fluid in the pleural space are often symptoms of pleural mesothelioma.
Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma. Detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to [[asbestos]] or [[radiation]].Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to [[asbestos]]. Symptoms of mesothelioma include [[chest pain]] nonpleuritic in nature, [[shortness of breath]], [[cough]], [[fatigue]], [[palpitation]], [[hemoptysis]], [[fever]] and [[weight loss]].
==History==
*Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma.<ref name="Riskfactorsformesothelioma1">Risk factors for mesothelioma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/mesothelioma/risks/?region=on. Accessed on February 16, 2016</ref><ref name="pmid29507793">{{cite journal |vauthors=Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A |title=Clinical diagnosis of malignant pleural mesothelioma |journal=J Thorac Dis |volume=10 |issue=Suppl 2 |pages=S253–S261 |date=January 2018 |pmid=29507793 |pmc=5830561 |doi=10.21037/jtd.2017.10.09 |url=}}</ref>
*A detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to [[asbestos]] or [[radiation]].


Symptoms of [[peritoneum|peritoneal]] mesothelioma include weight loss and [[cachexia]], abdominal swelling and pain due to [[ascites]] (a buildup of fluid in the abdominal cavity). Other symptoms of peritoneal mesothelioma may include bowel obstruction, blood clotting abnormalities, [[anemia]], and [[fever]]. If the cancer has spread beyond the mesothelium to other parts of the body, symptoms may include pain, trouble swallowing, or swelling of the neck or face.
==Symptoms==
*Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to [[asbestos]]. Symptoms of mesothelioma include [[chest pain]] nonpleuritic in nature, [[shortness of breath]], [[cough]], [[fatigue]], [[palpitation]], [[hemoptysis]], [[fever]] and [[weight loss]]. As the tumor grows in size, it may present with one or more symptoms. Symptoms of mesothelioma depend on the location of the tumor.<ref name="pmid18709470">{{cite journal |vauthors=Yang H, Testa JR, Carbone M |title=Mesothelioma epidemiology, carcinogenesis, and pathogenesis |journal=Curr Treat Options Oncol |volume=9 |issue=2-3 |pages=147–57 |date=June 2008 |pmid=18709470 |pmc=2717086 |doi=10.1007/s11864-008-0067-z |url=}}</ref><ref name="pmid295077932">{{cite journal |vauthors=Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A |title=Clinical diagnosis of malignant pleural mesothelioma |journal=J Thorac Dis |volume=10 |issue=Suppl 2 |pages=S253–S261 |date=January 2018 |pmid=29507793 |pmc=5830561 |doi=10.21037/jtd.2017.10.09 |url=}}</ref>


These symptoms may be caused by mesothelioma or by other, less serious conditions.
'''Mesothelioma that affects the pleura can cause:'''
*[[Chest pain]]  
*[[Shortness of breath]]
*[[Cough]]
*[[hemoptysis|Blood in sputum]]
*[[Fever]]
*[[Sweating]]
*[[Fatigue]]
*[[Weight loss]]
*[[dysphagia|Difficulty in swallowing]]


Mesothelioma that affects the pleura can cause these signs and symptoms:
'''Mesothelioma that affects the peritoneum can cause:'''
* chest wall pain
*[[Abdominal pain]]
* pleural effusion, or fluid surrounding the lung
*[[Abdominal distension]]
* shortness of breath
*[[abdominal mass|Lump in the abdomen]]
* fatigue or anemia
*[[Fatigue]]
* wheezing, hoarseness, or cough
*[[Weight loss]]  
* blood in the [[sputum]] (fluid) coughed up


In severe cases, the person may have many [[tumor]] masses. The individual may develop a [[pneumothorax]], or collapse of the [[lung]]. The disease may [[metastasize]], or spread, to other parts of the body.
'''Mesothelioma that affects the pericardium can cause:'''
*[[Palpitation]]
*[[Cough]]
*[[Hemoptysis]]
*[[Dizziness]]
*[[pedal edema|Swelling in legs]]
*[[Fatigue]]
*[[Night sweats]]


Tumors that affect the abdominal cavity often do not cause symptoms until they are at a late stage. Symptoms include:
* abdominal pain
* [[ascites]], or an abnormal buildup of fluid in the abdomen
* a mass in the abdomen
* problems with bowel function
* weight loss
==References==
==References==
{{reflist|2}}
{{reflist|2}}
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[[Category:Occupational diseases]]
[[Category:Occupational diseases]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]

Latest revision as of 14:35, 19 March 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma. Detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to asbestos or radiation.Presenting symptoms of mesothelioma appear after 20 to 50 years of exposure to asbestos. Symptoms of mesothelioma include chest pain nonpleuritic in nature, shortness of breath, cough, fatigue, palpitation, hemoptysis, fever and weight loss.

History

  • Obtaining the history is the most important aspect of making a diagnosis when evaluating a patient for mesothelioma.[1][2]
  • A detailed history of the presenting symptom (onset, duration, and progression), other associated symptoms, and a thorough family and occupational history review. Other specific areas of focus include a history of any exposure to asbestos or radiation.

Symptoms

Mesothelioma that affects the pleura can cause:

Mesothelioma that affects the peritoneum can cause:

Mesothelioma that affects the pericardium can cause:

References

  1. ↑ Risk factors for mesothelioma. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/mesothelioma/risks/?region=on. Accessed on February 16, 2016
  2. ↑ Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.
  3. ↑ Yang H, Testa JR, Carbone M (June 2008). "Mesothelioma epidemiology, carcinogenesis, and pathogenesis". Curr Treat Options Oncol. 9 (2–3): 147–57. doi:10.1007/s11864-008-0067-z. PMC 2717086. PMID 18709470.
  4. ↑ Bianco A, Valente T, De Rimini ML, Sica G, Fiorelli A (January 2018). "Clinical diagnosis of malignant pleural mesothelioma". J Thorac Dis. 10 (Suppl 2): S253–S261. doi:10.21037/jtd.2017.10.09. PMC 5830561. PMID 29507793.


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