Granulomatosis with polyangiitis epidemiology and demographics: Difference between revisions
| Line 5: | Line 5: | ||
==Overview== | ==Overview== | ||
The incidence of Granulomatosis with polyangiitis in children ranges form 0.03 to 3.2 per 100,000 per year. The prevalence in the United States is 3 per 100,000 persons. The mean age of diagnosis of granulomatosis with polyangiitis is 58 years. The disease most commonly presents in patients that are either middle aged or elderly. The mean age of diagnosis | The incidence of Granulomatosis with polyangiitis in children ranges form 0.03 to 3.2 per 100,000 per year. The prevalence in the United States is 3 per 100,000 persons. The mean age of diagnosis of granulomatosis with polyangiitis is 58 years. The disease most commonly presents in patients that are either middle aged or elderly. The mean age of diagnosis in children is between the ages of 4 to 17. Males are more commonly affected with Granulomatosis with polyangiitis. The overall male to female ratio is approximately 1.2 to 1. In children females are more commonly seen with the disease. Granulomatosis with polyangiitis typically affects Caucasians. | ||
==Epidemiology== | ==Epidemiology== | ||
Latest revision as of 18:41, 27 March 2018
|
Granulomatosis with polyangiitis Microchapters |
|
Differentiating Granulomatosis with polyangiitis from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Granulomatosis with polyangiitis epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Granulomatosis with polyangiitis epidemiology and demographics |
|
FDA on Granulomatosis with polyangiitis epidemiology and demographics |
|
CDC on Granulomatosis with polyangiitis epidemiology and demographics |
|
Granulomatosis with polyangiitis epidemiology and demographics in the news |
|
Blogs on Granulomatosis with polyangiitis epidemiology and demographics |
|
Directions to Hospitals Treating Granulomatosis with polyangiitis |
|
Risk calculators and risk factors for Granulomatosis with polyangiitis epidemiology and demographics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]Amandeep Singh M.D.[4]
Overview
The incidence of Granulomatosis with polyangiitis in children ranges form 0.03 to 3.2 per 100,000 per year. The prevalence in the United States is 3 per 100,000 persons. The mean age of diagnosis of granulomatosis with polyangiitis is 58 years. The disease most commonly presents in patients that are either middle aged or elderly. The mean age of diagnosis in children is between the ages of 4 to 17. Males are more commonly affected with Granulomatosis with polyangiitis. The overall male to female ratio is approximately 1.2 to 1. In children females are more commonly seen with the disease. Granulomatosis with polyangiitis typically affects Caucasians.
Epidemiology
Incidence
- The incidence of Granulomatosis with polyangiitis in Europe ranges from 3 to 14.4 per million per year.[1]
- The incidence of Granulomatosis with polyangiitis in children ranges form 0.03 to 3.2 per 100,000 per year.[2]
Prevalence
- The prevalence of Granulomatosis with polyangiitis in Europe ranges from 23.7 to 160 per million persons.[1]
Demographics
The rate distribution of Granulomatosis with polyangiitis varies upon age, sex, and race.
Age
- Patients of all age groups may develop Granulomatosis with polyangiitis.
- The mean age of diagnosis of granulomatosis with polyangiitis is 58 years.
- The incidence of the disease in female patients is 70 to 79 years of age and in male patients older than 80 years.[1]
- The disease most commonly presents in patients that are either middle aged or elderly.[5][6][7]
- The mean age of diagnosis of Granulomatosis with polyangiitis in children is between the ages of 4 to 17. However, the disease is rarely seen in children.[2]
Gender
- Males are more commonly affected with Granulomatosis with polyangiitis.
- The overall male to female ratio is approximately 1.2 to 1.[1]
- In children females are more commonly seen with the disease.[8]
Race
- Granulomatosis with polyangiitis typically affects Caucasians.
- Other races can be affected, however the rate is lower than that of Caucasians.[1][9]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Catanoso M, Macchioni P, Boiardi L, Manenti L, Tumiati B, Cavazza A; et al. (2014). "Epidemiology of granulomatosis with polyangiitis (Wegener's granulomatosis) in Northern Italy: a 15-year population-based study". Semin Arthritis Rheum. 44 (2): 202–7. doi:10.1016/j.semarthrit.2014.05.005. PMID 24932888.
- ↑ 2.0 2.1 Cabral DA, Uribe AG, Benseler S, O'Neil KM, Hashkes PJ, Higgins G; et al. (2009). "Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood". Arthritis Rheum. 60 (11): 3413–24. doi:10.1002/art.24876. PMID 19877069.
- ↑ Cotch MF, Hoffman GS, Yerg DE, Kaufman GI, Targonski P, Kaslow RA (1996). "The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources". Arthritis Rheum. 39 (1): 87–92. PMID 8546743.
- ↑ Muller K, Lin JH (2014). "Orbital granulomatosis with polyangiitis (Wegener granulomatosis): clinical and pathologic findings". Arch Pathol Lab Med. 138 (8): 1110–4. doi:10.5858/arpa.2013-0006-RS. PMC 4140401. PMID 25076302.
- ↑ Koldingsnes W, Nossent H (2000). "Epidemiology of Wegener's granulomatosis in northern Norway". Arthritis Rheum. 43 (11): 2481–7. doi:10.1002/1529-0131(200011)43:11<2481::AID-ANR15>3.0.CO;2-6. PMID 11083271.
- ↑ Watts RA, Lane SE, Bentham G, Scott DG (2000). "Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom". Arthritis Rheum. 43 (2): 414–9. doi:10.1002/1529-0131(200002)43:2<414::AID-ANR23>3.0.CO;2-0. PMID 10693883.
- ↑ Gonzalez-Gay MA, Garcia-Porrua C, Guerrero J, Rodriguez-Ledo P, Llorca J (2003). "The epidemiology of the primary systemic vasculitides in northwest Spain: implications of the Chapel Hill Consensus Conference definitions". Arthritis Rheum. 49 (3): 388–93. doi:10.1002/art.11115. PMID 12794795.
- ↑ Bohm M, Gonzalez Fernandez MI, Ozen S, Pistorio A, Dolezalova P, Brogan P; et al. (2014). "Clinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis)". Pediatr Rheumatol Online J. 12: 18. doi:10.1186/1546-0096-12-18. PMC 4041043. PMID 24891844.
- ↑ Mohammad AJ, Jacobsson LT, Mahr AD, Sturfelt G, Segelmark M (2007). "Prevalence of Wegener's granulomatosis, microscopic polyangiitis, polyarteritis nodosa and Churg-Strauss syndrome within a defined population in southern Sweden". Rheumatology (Oxford). 46 (8): 1329–37. doi:10.1093/rheumatology/kem107. PMID 17553910.